We came out of the cycle with one normal fertilised egg, should we get it tested for genetic abnormalities?

[Venster]

It looks like I have a polyp... we only have one egg after a round of IVF stims. Should I do as much as possible to make sure the uterine environment is perfect and risk the embryo dying in the genetic testing/freezing/thawing process? Or should we just throw caution to the wind and try a fresh transfer knowing that everything isn't perfect?

[Skittles11]

Hello I think it probably depends on your history as to whether you should test the embryo. Has it already made it to blastocyst?

If you have a history of miscarriage or perhaps you know you have had chromosomally abnormal embryos in the past then it could be worth testing to give you peace of mind. But if you have not had this type of history I personally would probably be inclined to give it a shot as it is. You could try and make sure the uterine environment is as receptive as possible through things like EMMA and ALICE testing but it would depend how far you'd want to push the testing before putting the embryo back- as I'm sure you know all the testing takes time!

Good luck with your decision x

[Kotick83]

I personally would go for it...nothing will always be 100% perfect and I wouldn't do embryo testing for just the one (my two cycles we only had 1 blast each and I never tested them). It will be better back where it belongs than in the lab...

[Tamaa]

I would quote my embryologist's advice 'Testing does not increase the chances of pregnancy. What it increases is, mental peace/answers to if it doesn't work.'So it's a personal choice I would say.

Personally I would get it transferred rather than testing.

All the best for your journey.

[Jumpppy in reply to Tamaa]

Tamaa this is great advice and spot on 😀 Thanks for sharing-I wish all embryologists were this helpful...

[ourbundleofjoy in reply to Tamaa]

I agree with Tamaa. We had 1 blastocyst that we PGT-A tested, and before transfer we did EMMA, ALICE, ERA, NK. Unfortunately we were not successful. It was heartbreaking. There is no guarantee it will work. In hindsight I would not test only 1 blastocyst, but that is my opinion. Venster, there is actually no right answer. You just need to do what is right for you. I wish you all the best

[km307]

I’m doing a fresh cycle at the moment and have just turned 43. I’ve had two miscarriages from embryos created at 40.5 most likely due to chromosomal abnormalities. My consultant only recommends testing if I get three or more embryos, otherwise he said just to put them back in and see what happens. Testing isn’t a perfect science and doesn’t increase pregnancy chances, just prevents some failed cycles. With only one I’d definitely chance it for a transfer. Good luck!

[LSandJ]

Agreed, just go for it IF the polyp isn't going to be in the way? (Depends where it is and how big and if the doc is worried by it??)

[Blessed18]

I had 3 miscarriages, 1 ectopic, if I were you i still won't tested an embryo. My only reason is because it doesn't guarantee a live birth non euploid embryos/mosaic embryos can still produce a healthy baby.

I didn't on my last transfer. Even when the clinic was adamant due to my history. That embryo is now 11 weeks old.

We did however used MACS and PICSI for the sperm selection/sorting .

[Twiglet2]

I wouldn’t test just one embryo but if it’s reached blastocyst stage and good enough to freeze I might be tempted to do that if your consultant doesn’t think you are as receptive for fresh transfer as you could be with a month or so more prep. If they say it’s not an issue then I’d just do the fresh transfer tbh xx

[Football61]

Hi. Just to put across another point of view here. I appreciate that PGT-A testing doesn’t increase your chances of a live birth, but it can be helpful if you are over 40. I’m 44 and on a major race against the clock - and so I don’t have time to keep transferring potentially non-viable embryos and waiting to see what happens. I guess it depends upon each person’s particular circumstances. Wishing you the very best of luck x