another bfn

[Lyndsbaby]

We've just had a BFN on OTD. This is my seventh transfer after six cycles - the first 5 were in Scotland but we changed to a clinic in Greece for the latest one. I've never even had a positive result in any of those transfers - no chemicals, no miscarriages. I've had 4 pregnancies naturally but they were miscarriages or ectopic so other than my age (40 now but just turned 38 when we started IVF) I can't work out how we can't even get to the stage of an initial positive now. Really deflated. We have another go in Greece and I'm sure I'll be fine in a day or two but just now I can't face another possible disappointment. I was so so nervous to take the test today for that reason. Anyone be lucky after so many negatives?

[Elmo13]

Hi, couldn’t read this and run. Just wanted to say I’m so sorry. This whole process can cruel and isolating and just rubbish!

Please take care of yourself and although it’s difficult, try and keep some hope for the next cycle. There are many ladies on here who’ve had multiple negatives and then they get their positive. It’s possible! Sending hugs. X

[Lyndsbaby in reply to Elmo13]

Thank you. I need to just remind myself that hopefully I'll have a child through some method whether donor eggs or adoption. It's not an easy process for all us ladies with fertility issues. Thanks for taking the time to reply xx

[Ganges]

I’m in the same boat numbers wise I’m afraid. Also just turned 40 and had started this process aged 37. It’s not easy, but you do read about lucky people who have to go through a lot of transfers. 🤞🏼 it’s us too!

I was looking at going abroad, but don’t think I can take all that time off work. So all of my 6 transfers have been UK. 2 were nhs.

Good luck x

[Nevergu]

I'm so sorry. I'm in a similar position after 6 failed transfers. I had live birth 10 years ago conceived naturally but since then 2 x mc and 6 failed ivf transfers. Never had even a chemical since I started my ivf journey at age of 40. Spent thousands on immune treatments, had a hysto , changed 3 clinics and nothing. About to have another transfer and instead of excitment im full of anxiety. All I want is those two lines ... I hope that we will get there one day. One thing to consider is embryo testing if you haven't done already and natural modified transfer

[rainbowbaby8320 in reply to Nevergu]

I noticed your reply and I just wanted to say how sorry I am for you too! You have been through a lot! I have just had a hysto (all clear) and now I'm taking out my breast implants as a precaution, and they will give me intralipids next... I guess that's what you meant by immune drugs? I can't believe they still didn't work for you! This must be devastating xx

[Nevergu in reply to rainbowbaby8320]

Yes, I did intralipids, steroids, levonox ect and still no positive test. My hysto came back clear too! I just don't know where to turn. Different clinics, different Dr's and immunology specialists, I tried them all! Pgt tested embryos too due to age- and nothing! I hope you don't have to go through this, mentally it's very hard xx

[rainbowbaby8320 in reply to Nevergu]

this is very sad... and scary because my journey has been simillar to yours so far...I am considering where I will draw the line because as you say, it's very draining and emotionally damaging I think! not to mention the finances - i'm sure i've spent £20- £30k already on my transfers and tests? I can't keep going like this...I feel angry that it might have been my covid jab because everything was fine before that?! It hasn't escaped my attention that alot of the women are saying 'in the last few years' they have been trying and don't get positives... (which sounds like covid vaccine). I used to think the anti vaccination people were crazy but now i'm wondering if they were right. We will never know probably!

It could be my implants though too, and they are coming out in July... i've just booked the op. But I had those when my son was conceived so it's weird...

[Nevergu in reply to rainbowbaby8320]

I had very bad reaction to my first covid jab too. I bled on and off for two months and developed a cyst that I never had before! We will never know but the timing seems right. Mentally I'm broken, financially I stopped counting as it would make me even more depressed. I just don't understand how I went from getting pregnant at first try to not being able to achieve implantation at all. No Dr can give me an answer despite changing a fortune for treatments xx

[Lyndsbaby in reply to Nevergu]

I'm so sorry to hear of your struggle too - really hope we both get the ending we dream of! I always thought I'd have at least 3 children - but I'd be more than delighted to have just one wee baba now!

[Twiglet2]

I’m so sorry 😢 xx

[rainbowbaby8320]

hello

Are you doing pgta?

Also, what grade are your embryos? I think it’s time to consider if there is something else wrong? Have you checked womb or anything?

Also, did you get the Covid jab? Another query which I hope you don’t mind is do you have breast implants? Covid jabs and breast implants both create auto immune disease in the body… I’ve had both and I’m struggling like you to get pregnant after transferring top quality blastocysts. The last one was pgta screened too…

I think you shouldn’t allow the consultants to mindlessly carry on transferring embryos ? That’s what they did with me and I regret it… if you Google, it says they should consider other issues after 3 failed attempts with good grade embryos… like I said on another post though… they are making lots of money while we are wasting precious time and money…

You might want to read the post I made about my body killing my embryos and all the responses I got re auto immune disease and the treatment for that! Most of those women went on to have a baby with the drugs for auto immune conditions…?

[rainbowbaby8320 in reply to rainbowbaby8320]

also I’m sorry you are going through this - it’s horrid xx

[rainbowbaby8320 in reply to rainbowbaby8320]

google.com/search?q=covid+v...

Hi

Just wanted to share the medical paper which confirms what I said about covid jab... it's causing a "new onset of auto immune diseases" in people... I don't think this is happening to everyone.. it also exacerbates exisiting conditions... There is a similar one about breast implants from the same medical organisation (think it's a gov medical paper in US).

[rainbowbaby8320]

Hi Lyndsbaby... just another question! do they know why you miscarried the other ones? Are all the chromosaomes there? My friend had multiple miscarriages and they did a test and found a chromosome was missing... she went on to have a lovely little boy after this... (naturally)... not sure how she fixed it... might be something in her diet was missing!

[Lyndsbaby in reply to rainbowbaby8320]

Hiya. The first miscarriage wasn't really a miscarriage as such - I was only 20 and it was twins (a bit of an accident). They came too early at just a day before 24 weeks. Two little girls. One wasn't strong enough after birth but the other made it to 7 weeks and 3 days and sadly passed away. I didn't try for a baby until I was married just before my 33rd birthday. We fell pregnant when I was 34 and that was the second miscarriage at 7 weeks but didn't do any testing as I know it's not uncommon and stupidly thought we'd fall again soon. My first ectopic was when I was 36 - we'd started investigations with the nhs by this point and the ectopic happened just after I had a hysterosalpingography that has come back normal! Anyway that's where my problems started I think as I had another ectopic at 37 just as covid happened. We went private after things reopened and they said my tubes were damaged so they were clipped to give ivf a better chance. The latest clinic did all the tests before this last attempt - checking immune and bacterial issues. I had a hysteroscopy and implantation cuts too. Nothing showed up on the tests - almost hoped it had as it would be something to fix! I had the covid jabs in 2021 but no boosters since - no breast implants. I've not done pgta as most rounds we've only had one blastocyst to transfer - only once did we get to freeze one. The grades have varied from a to c - we have had two a grade transferred - the first one and then the frozen one x

[rainbowbaby8320]

Aww you have been through a lot of stress - I'm really sad for you

Some of the other women said that they tested negative for immune issues but were given the drugs anyway and then got their baby? My own consultant said there are hundreds of auto immune diseases and they may not test the right ones... so my current clinic's policy is to just give the drugs? They didn't do this before - just now only, because my last one was pgta ok and still didn't work - so they have ruled out egg quality now...if it wasn't PGTA tested they would probably still be saying maybe it's egg quality and we need to get the right egg! There are some other women who told me their clinic gave the meds as a 'precaution' anyway. If I end up finding the meds work it means I might have been pregnant before now, had my clinic taken that approach too?

At my last fresh cycle I ended up with two B grades - i'm 41 years... one was euploid and the other wasn't...? So my view is that it's worth doing PGTA as you can rule out egg quality as an issue, or know that it is egg quality? It also saves time with miscarriages - the rate is about 6% at 40+ instead of 30%... My friend that had the miscarriages had a few of them and one went on for six months - if that happens to me, then I've also got egg quality issue too as they will be older? Time is very precious isn't it! Plus it wasn't nice to go through the miscarriage either.

After that last one didn't work for me, it gave me ammunition to start checking other things? I might never have another baby... But I want to at least be ruling out problems (as you said) before I stop trying...?

[rainbowbaby8320]

Are they willing to give you the drugs for auto immune conditions anyway? Perhaps you could ask them? It seems like you have ruled out a lot of issues, but it must be 'something'...? With the treatment you have had, is the ectopic pregnancy issue fixed? I don't know much about that but presume because they put the embryo straight into the womb, it's not relevant through IVF? Is that right?

[Lyndsbaby in reply to rainbowbaby8320]

I was on prednisone which I think is for the immune system - but not intralipids. I'll ask at our review meeting if the clinic don't suggest it. Thanks for the tip. Yeah I had a hydrosalpinge which is a damaged tube full of liquid. I was told the liquid can affect implantation/cause miscarriage if it leaks into the womb, so having the tubes clipped prevents that - that's right that you don't really need the tubes for IVF but to maintain blood flow to the ovaries they didn't remove them completely but clipped them close to where they meet the uterus. x

[rainbowbaby8320]

Ah I see.. and that drug still didn't work! hmmm? Not sure what else to suggest! I wish I had the answer for you... that makes sense re your ectopic treatment etc.... so it 'must' be something else? I think this is where PGTA might help then? because how do you know if those embryos were euploid or not? I wish I could tell you the answer x

[rainbowbaby8320 in reply to rainbowbaby8320]

sorry just another thought! they also said they will give me clexane (?) spelling! and asprin...? must be to do with the blood and the embryo being prevented from implanting due to clotting or something? Have you been given blood thinners yet?

[Lyndsbaby in reply to rainbowbaby8320]

No problem - I'm not sure the clinic in Greece does PGTA testing. I was given clexane, aspirin as well as progesterone and estrogen. All that was new this round so I thought that might make the difference.

[rainbowbaby8320 in reply to Lyndsbaby]

I'm really sorry it didn't work. It must be devastating! xx

[Positive20]

Hi Lyndsbaby. Gosh my heart goes out to you. I started IVF 3.5 years ago. 6 goes till I got a positive pregnancy and prior to that only one miscarriage at 6 weeks. Drs couldn’t suggest anything different to try as didn’t know why it wasn’t working. We had this one go as our last and it worked. I’m so sorry you have had recurrent negatives and know what it’s like xxxx thinking of you xxxx

Also, just to add in, when I had my miscarriage there was no reason for it and down to chromosomes abnormalities. I also wouldn’t have any of my covid jabs whilst having treatment but decided in the end it wasn’t making any difference so I might as well have them (including the booster) as I am at risk on my job. After having all the jabs I finally got pregnant so it made no difference to me having the jab.

[Lyndsbaby]

Aw that's lovely news - so pleased for you! Maybe 7th time lucky - to be fair it will only be our second attempt at the new clinic so maybe they can adjust a few things this next time around or I'll just be lucky!

[Elizabeth1988]

I’m so sorry, I really had everything crossed for you. So unfair. Be kind to yourself. If you do decide to move to donor eggs, here to chat. Xx

[Lyndsbaby in reply to Elizabeth1988]

thank you! I'll definitely take you up on that kind offer. I hope you are keeping well and being able to enjoy the early stages of pregnancy xx