Clomid + 150iu menopur

[Nufc30]

So here goes Cycle round 2, first round 3 eggs 2 fertilised 1 blast made it and was frozen -it was through delayed icsi - so no Fresh transfer; the cycle was cancelled. I have Low amh 5.4 + stage 3 endo.

The aim is to have a Fresh transfer this time.I was put on Clomid for 5 days+ 150iu menopur. Introduced fyremadel on day 6. Not sure whether this is classed as mini ivf.

My follicles developed much better this time with the lower dose of menopur ( was on 450iu first time around) I had 6 follicles all of a similar size,19-21mm. They managed to retrieve 4 eggs of which 3 have fertilised the other 2 follicles didn't have an egg in them. I'm quite happy about with the results so far as I know I will not make more than 7 follicles in a cycle.

Now just waiting for Thursday to see if they develop to day 5.

Has anyone else been on a protocol like this?

[Candlewax3]

Hi, how did you get on with this protocol?This is what my doctor has suggested for our 3rd round 🤞🏼

[Nufc30 in reply to Candlewax3]

Hey candlewax. This protocol worked well for me. I ended up stimming for 9 days and then trigger, follicles developed at better rates than previous cycles. All 3 reached day 5 and we're good quality. 2 were frozen and fresh transfer of the best one. I'm now currently pregnant and 14 weeks and everything going well so far

I hope this works for you too and 3rd time lucky, I found that I had a better response with lower dosage and less side effects and just felt better about the whole combination of drugs. My consultant knew I wasn't going to make alot of follicles so just concentrated on ensuring that the follicles were of good quality.

Were your previous cycles higher doses?

[Candlewax3 in reply to Nufc30]

Oh that is so good to hear. Congratulations!! Both my previous cycles were long protocol at 275, round 1 was Gonal F and round 2 Menopur.

I responded well to both 7 fertilised round 1, 6 round 2 but only 1 of them made it to day 3 for a transfer which failed.

I lost both my Fallopian tubes last year to ectopics but apart from my tube issue all other levels are good so now they are thinking my egg quality is maybe getting damaged by the higher dose 🤷‍♀️

[Nufc30 in reply to Candlewax3]

Thank you . Sorry to hear you've had such a tough time. I hope this protocol works for you and I also did think the same when I was on max menopur. It's all a bit of trial and error sometimes for what works for you. I also took alot of vitamins before the second time round and sorted out the diet so maybe that contributed too. Wish you all the best xx

[Beclp in reply to Nufc30]

Sorry to just join in to this convo. This is great news 🙏I am just about to start a similar protocol also after doing 2 cycles on max stims. I’ll be on 265 of menopur so a bit higher than you were taking.

Both cycles on max stims were a bust.

Glad to hear you had a positive result!

Can I ask how the protocol went exactly.

Did u take the clomid from day 1 and right through to trigger or do you stop taking it when you start the injections ??

Thanks 💕

[Nufc30 in reply to Beclp]

Hi , no worries, thank you. Day 1 was just clomid. Day 2 - 5 was clomid and menopur. Day 6 was just menopur. Day 7 and 8 was menopur and fyremadal and day 9 was menopur fyremadel and my trigger ovitrelle. Good luck with your cycle! Everything just happened more smoothly this time for me and I hope it goes well for you too. Xx

[Beclp]

Thank you 🙏💕

[Bonnieex]

Switching to a lower dose of Menopur seems to have made a positive difference for your follicle development, and getting 3 fertilized eggs from 4 retrieved is a solid outcome. Fingers crossed for your embryos to make it to day 5!

Personally, I’ve only used Clomid(ordered here health-delivery24.com/buy-c..., and it worked well for me. It’s a reliable option for stimulating ovulation, especially in combination protocols like yours. While I didn’t pair it with Menopur, I’ve read that adding gonadotropins like Menopur can really enhance follicle growth in cases where egg reserve is low. Your results so far seem to reflect that balance—controlled stimulation without overstimulation.

I hope this round brings you success with a fresh transfer! ❤️