Second Failed IVF Round - Endo & PCOS

[Ljayne]

Hello All, I am sad to say that my FET was not successful and this time round, I am hurt and shocked, far more than my first round.

I have stage 4 endometriosis and PCOS, both my embryo transfers have been one year apart due to Covid. However, the second time round I was more hopeful as I had stuck to a very strict PCOS diet which had significantly reduced inflammation and period pain with my endo.

In addition to this, I'd reduced my sugar intake, caffeine and alcohol. I have been receiving acupuncture weekly and taking part in yoga. I have also been taken a range of supplements recommended by my acupuncturist.

My fertility doctor did say that frozen embryo transfers are more successful than fresh as you aren't having the additional hormones and treatment within the same month.

This time round, I also didn't come on my period early unlike my first fresh round so it was heart breaking when I turned over my test and it was negative.

I have two frosties left and I am concerned that future rounds will not work as this was my best chance. I'd lost weight, my health has never been better and my symptoms had reduced.

Prior to my egg retrieval I had a laparoscopy to remove adhesions, cysts etc. and 2/3 months prior to my second round I had a hysteroscopy to remove some polyps and adhesions.

I have a phone call with my fertility consultant next week, what types of questions should I be asking? This is through the NHS who in terms of staff are absolutely fantastic, but due to time constraints I am literally in and out. You have to really prepared as you do not get (or at least I don't) much time to discuss concerns or ask further questions.

Is anyone in my boat? The quality of my embryo was 4AB and this time 4BA and I had a hysteroscopy to remove adhesions and polyps. I know it's the million dollar question that we'd all like to know but why didn't it work? Has anyone been in a similar position and received constructive advice?

I cannot bear to put myself through this again if my uterus has little chance of allowing my embryos to attach and grow. The only things this time round that I wish would have been done differently is the embryo transfer causes me alot of pain. I know that's not usual but I am also not the only one and I didn't have the endo scratch as my fertility consultant forgot about it but I know that this doesn't yet have any significant evidence.

Any constructive advice would be really helpful - and I ask this in the most nicest way possible, please only share concrete advice, I know some people try to help but saying to not stress and it will happen when the time is right is kind - but I am looking for something more concrete and constructive x

[Lapinblanc88]

Wow, I'm really sorry for you. It looks like you did every thing you could! Great lifestyle changes! Well done!

I also went through similar life style changes 3 years ago for my first fresh cycle ( AIP diet, extremely difficult to follow, I have endo) and I have had better result last year when I drank more wine than I should and was less careful with my diet

I did read "it starts with the egg" to improve my egg quality as I was 38. Highly recommend it!!

and my drug protocol was v different + growth hormones and scanned every 2 days.

Also down reg for 3 weeks ahead and took extra progesterone ahead of my frozen transfer.

Pgs my embryos

I'm finally pregnant after 5 years of trying

It could be an issue with egg quality. How old are you? Could be your uterine environment with endometriosis.

I opted to have a hycosy test ahead of my transfer.

[Ljayne in reply to Lapinblanc88]

Hello and thank you for sharing your experience! It's really nice and interesting to read.

I turned 31 last month, my husband however is 46. We had ICSI has his sperm count was fine, just low motility.