Poor Blastocyst Quality

[Westielover16]

Hi All,

Yesterday we had our 5dt and luckily transferred 2 blastocysts. I was feeling okay yesterday but today I’m struggling and really worried about the quality of the embryos. The clinic said they were early blastocysts and neither was suitable for freezing.

This is our 4th fresh cycle. First 2 just failed, 3rd was a chemical pregnancy and 4th was a FET which miscarried at 6 weeks. I’m 38 and hubby is 41.

This cycle all around has not been ideal. I had a horrible cold the whole way through stimming and I had a small early LH surge. Luckily the clinic was able to get things under control tweaking my meds but I’m just extra worried about the outcome given the rocky journey we’ve had this cycle.

The 2 blastocysts transferred were graded as 2AC and 1BB. Previously we’ve had top quality embryos so feeling very nervous this time.

Just wondering if any of you have had success with early blastocysts or poorer quality embryos?

Thanks for any advice and positive thoughts!

[Hidden]

I had 3 poor quality blastos transferred and got my bfp. I did go on to MC but that was nothing to do with embryo quality

Over my ivf journey I have learnt that grading means so little .. you hear of success from a day 2 terrible quality embryo but a bfn from a double transfer of top quality embryos. I think so much is luck and fate .. don’t despair - you are PUPO and I really hope this continues!! Try not to obsess (impossible!) masses of luck xx

[Westielover16 in reply to Hidden]

Hi Daisy1245,

Thanks for your positive message and you are so right that it’s best to focus on being PUPO.

So sorry to hear about your loss. This process can be so cruel at times. Wishing you all the best for wherever this crazy journey takes you next.

[Hidden in reply to Westielover16]

Its nigh on impossible not to spend your whole time googling. I am an expert at that.. but fundamentally its all out of our control - which lets face it is why its so ruddy difficult!

ive got a good feeling about this xx

[Jaygee]

Hello! I have also had 2 poor quality blastos transferred. I’m 4dp5dt. I am pretty sure the cycle is a flop and not holding out for a positive. If people with 5AA embryos can fail i think my chances are slim, but then again I’m a bit of a pessimist and rather tell myself it’s failed, as if it does end up BFN I’m not too disappointed. If it’s BFP then all the better! I think it’s just my coping strategy but I’ve seen people end up pregnant with low quality blastos so don’t get disheartened yet!! Fingers crossed for you x

[Westielover16 in reply to Jaygee]

Hi Jaycee,

I can be really similar to how you describe yourself. As we’ve not had an ideal cycle I went into the transfer telling myself that it would only be one to transfer, to not get my hopes up. Then when they said we had 2, I was initially so excited. We had a plan to transfer one and freeze one if we got 2, so was heartbroken when they said neither was good enough quality for freezing.

It’s all just such a rollercoaster! Trying to stay positive and hope for the best, but it’s a real struggle at times. Just trying to remind myself the last 2 transfers we had were top quality and we got a chemical pregnancy and a miscarriage so it really is just luck.

Wish you all the best for your cycle and fingers crossed 🤞

[Kat9lives]

Hi lovely, try not to focus on the grading, they can change all the time and it really means nothing once they've got to a transfer stage. It's a way for the embryologist to choose the "best" embryo(s) to put back in, based on their quality at that time. Try as best as poss to relax and focus on positive thoughts... it's down to fate now but a stress free mind can help. Best of luck xx

[Westielover16 in reply to Kat9lives]

Thanks for your positive message Kat9lives. Just trying to keep busy and stay positive.

[Nay1986]

On my 1st shot at IVF I got told my two 5 day embies weren't the best quality, I've now got a beautiful 10 month old daughter ❤️ Daisy is right, most of it is luck and fait, everything crossed for you 🤞❤️ x

[Westielover16 in reply to Nay1986]

Thanks Nay1986. Really helpful to hear the positive outcome from your story. Will keep fingers crossed we have a similar happy ending!

[Running79]

I’ve just had a 3BB FET last Friday, I spoke to the consultant who did it about the fact that I had a 5BB put back previously and it ended in MC. She advised that the headings mean nothing really, so in my mind I don’t know why they bother telling you, I’ve read stories of ladies having really low grades put back and have success - so my advice is don’t worry about it, and see what happens

[Westielover16 in reply to Running79]

Hi Running79,

Wishing you the best of luck for your cycle!

We’ve had top quality before and they ended up as a chemical pregnancy and miscarriage, so I know quality grading isn’t a guarantee. It really is just luck at this stage. Definitely agree they shouldn’t tell you the grades as just stresses me out.

Will just try and stay busy and focus on the many positive stories I’ve heard/read re successes.

Will keep my fingers crossed for you as well 🤞

[DiamondRuby128]

Hi, a friend I used to work with had 3 rounds of IVF and now has 3 children (twins for one cycle). Every time she had poor quality eggs and embryos so it is possible. Don’t give up hope just yet. Let nature take it course. There is nothing else you can do at this stage so be kind to yourself, keep busy, do nice things. I’m keeping everything crossed for you. Xxx

[Westielover16 in reply to DiamondRuby128]

Thanks DiamondRuby128! It’s always great to hear stories with happy outcomes like this. With stay positive and keep my fingers crossed 🤞

[Hidden]

Agreed, grading is just a beauty competition what matters is what happens after you pick them up. Our grading was not brilliant out of our complete disbelief we are pregnant with number 2 from the same batch 😂 Dr was pretty shocked. Anyway I'm just trying to say anything could happen, good luck and all the best

[Westielover16 in reply to Hidden]

Hi Reewills1,

Thanks for your message and for sharing your happy ending. It’s difficult but definitely trying to stay positive.

[mary77777]

Hi. Grading is probably important up to a certain extent. Depending on the system, they can be graded up to E, while those up to C are generally considered transferable. BB is not bad. My doctor told me that some studies say that unperfect blastocyst will fight actually more to get implanted.

I transferred only one 5BB in February and will be 35weeks pregnant this week My clinic usually does single transfers and we chose to freeze the 5AB one.

Best of luck!

[Westielover16 in reply to mary77777]

Hi Mary,

Thanks for your message. Just trying to stay positive and focus on being PUPO. Fingers crossed we will have a happy outcome to this cycle.