Repeated implantation failure (RIF)

[mshf]

We have 3 embryo transfer but we have repeated implantation failure (RIF). My physician said to me: "Implantation failure is related to either maternal factors or embryonic causes. Maternal factors include uterine anatomic abnormalities, thrombophilia, non-receptive endometrium, and immunological factors. Failure of implantation due to embryonic causes is associated with either genetic abnormalities or other factors intrinsic to the embryo that impair its ability to develop in utero, to hatch, and to implant".The thickness of my endometrium was normal and my immunological factors(anti-phospholipid, anticoagulant, and lindane ) were normal. I did not any uterine anatomic abnormalities. I think the reason for repeated implantation failure is genetic abnormalities or other factors intrinsic to the embryo that impair its ability to develop in utero, to hatch, and to implant because DFI is high.embryologist said to me the grade of your embryo is low and you must transfer blastocyst. I have the intrauterine infusion of platelet-rich plasma (PRP) to promote endometrial growth but we have the failure.

[LegoBatgirl]

Really sorry to hear about your RIF, hope that your clinic can help x

[Lizzielizzielizzie]

My husband and I had karyotyping blood tests after repeated implantation failure and discovered that our embryos are poor quality because my husband carries a balanced chromosome translocation. It’s a small chance that this is your problem but you may want to ask about this test.

[Stacia]

i have no clue what that is but i know its disheartening. If the clinic knows possible reasons then they need to investigate further. My Dr suggested me that if this cycle fails then we should consider trying a donor sperm. i hope you`ll find answers and solutions soon. xxx