Feeling Despondent

[Caroliono4]

Out of our 11 good -sized follicles they managed to get 7 eggs. We got the call this morning that only 3 were mature and 2 of these have fertilised after ICSI (high sperm dna fragmentation). They have told me they want to put both back tomorrow. Having had 4 mcs after natural pregnancies I was really hoping we woukd have some blasyocysts for PGS testing as I really, really don't want to have another miscarriage. I know the ICSI may help slightly with the sperm issue but there's no knowing if both sperm and eggs are still abnormal.

I'm 43 so I knew it woukd be a long shot though my FSH, AMH and AFC are good. Originally we had thought donor eggs would be our only option but were persuaded otherwise.

I know the clinic thinks that inside me is the best place for the eggs but I'm wondering if I should insist they should wait to see if they become blastocysts. I know the sperm takes over on day 3 so think it could make sense to wait at least until then to see if they continue to develop normally.

Aarrrrgggghhh I still feel very odd after the drugs yesterday and don't know what to do

[7AVA]

Hi Caroliono - great to hear that you have 2 embryos to put back. I understand your dilemma with wanting them PGS tested. It is a difficult decision. I’m so sorry to hear of your previous miscarriages and understand that you would want to do everything you can to prevent that happening again. We had two embryos transferred back recently and decided not to go for PGS screening as we had read so many pros and cons we thought ultimately we wanted to give them a chance (unsuccessful this time). Ultimately it’s your decision and your clinic should be guided by you. Lots of luck xxx

[Caroliono4 in reply to 7AVA]

Thank you. Yes I think if they get to day 5 we will give them a chance. The embryologist also said we could push it to day 6 if they were slow and then freeze.

[Dunla]

I’m so sorry to hear things have been so difficult for you and understand why you are feeling despondent today about how things are progressing. From my own experience I have always had day two or three ET as I’ve never had more than two or three embryos. I’m sure it will probably be what your clinic advises you to do also. Wishing you the very best of luck for your transfer whatever decision you make xo

[Caroliono4 in reply to Dunla]

Thanks Dunla. Yes they definitely recommended the day 2 or 3 transfer but are happy to let me go to Day 5 as I understood the risks. Thanks for your support x x

[Hidden]

Hi Carolio, that’s a really tough decision. From what I know the uterus is a much better environment for embies. Some that might not survive in a lab environment will do much better inside. PGS is clearly important to you though and so long as you know that in pushing for day 5 you risk no transfer, then go for it. I can understand why you feel you’d rather know. Best xx

[Caroliono4]

Thank you all for your lovely, considerate messages, it has been a really difficult day. I haven't ever really cried about the miscarriages or dared to think we would get anywhere with OE ivf so think I have holding a lot in. We've decided to see if they will go to Day 5 and the embryologist is going to report back every couple of days. Even if they don't succeed I think this may help us to decide if we would also need donor sperm if we eventually go dowb the donor route.

[Tugsgirl]

I just want to wish you luck xx

[Caroliono4 in reply to Tugsgirl]

Thank you. You too wherever you are in your journey x

[Violet5451]

Hey,

This sounds like a difficult dilemma for you and There is nothing really that I can say to help. Apart from, I wish you lots of luck and hope that whatever is decided is the best option. Think about the options and possible outcomes from both and maybe that will help you come up with the answer?

Lots of luck xxx

[Lizzielizzielizzie]

No advice but just to let you know after only 3/9 eggs mature on my first round I now have a 37 hour trigger instead of 36 and have had much better maturity x

[Caroliono4 in reply to Lizzielizzielizzie]

Ah that's good to know. I did feel a couple of pains in my left ovary where my biggest follicles were before trigger so was wondering if I ovulated too early. They did the collection at 35 hours though so it could well have been a but too early.

[Lizzielizzielizzie in reply to Caroliono4]

Yes that definitely sounds too early. Hopefully you won’t need another round but if you do, you should definitely query that... I thought 36 hours was standard so can’t understand why they did that.

[ClarabGlasgow in reply to Lizzielizzielizzie]

Hi cariliono sorry to hear you have less eggs and embryos than anticipated. I think you are right to go with your gut. although the aim of ivf is a bfp I also think finding out more information from the way the whole process goes is also a very worthwhile takeaway. I think for you this is the screening so it’s important to see how things progress over the next few days. I am always looking for answers think I’d choose to keep developing in the lab during the whole 2 weeks if it was possible! I hope they make it to day 5! Also I didn’t realise the number of hours post trigger was so precise I was delayed by nearly an hour in being taken for ec & nobody even apologised to me or explained that it was an issue so thanks for sharing! X

[Caroliono4 in reply to ClarabGlasgow]

Thanks Clarab. Yes two weeks in the lab woukd be a lot less worry! Yesterday we only had 1left and I'm dreading the 9.30 update this morning but I still feel we did the right thing for our situation. It appears that more and more clinics seem to be waiting til day 5 to transfer.

[Lizzielizzielizzie in reply to Caroliono4]

Good luck xx