Low fertilisation rate after ICSI - a... - Fertility Network UK

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Low fertilisation rate after ICSI - any experiences?

LCharlton profile image
14 Replies

We have male factor infertility - now on our first round, and last week we had 12 eggs collected, 8 mature but only 3 fertilised after ICSI. Yesterday (Day 3), the embryologist told me all three were looking very good quality, but warned me that we might see a big change between day 3 and day 5 (Tuesday) when our transfer is planned. Has anyone else had a low fertilisation rate after ICSI, and if so did the embies fail to make blastocyst?? I'm worrying now!

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LCharlton profile image
LCharlton
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14 Replies
KiboXX profile image
KiboXX

Hi LCharlton,

It’s great that all 3 that fertilised are still looking very good!

We always had similar fertilisation numbers and we always had one or two make it to day 5 so try not to worry too much!

On our last round we had three looking good on day 3 and all of them made it day 5 so you never know!

Keeping everything crossed for you xx

LCharlton profile image
LCharlton in reply toKiboXX

That's really reassuring, thank you xx

DianeArnold profile image
DianeArnoldPartnerNurseFertility Network UK

Hi Charlton. Looks like the three embryos you have mean to grow on, so fingers crossed you will get transfer on Day 5. I shall be thinking of you. Diane

LCharlton profile image
LCharlton in reply toDianeArnold

Thanks Diane!!

L400ynd profile image
L400ynd

Stop worrying!!! ❤️❤️❤️. Stay away from google as well. 😂😂. Xxx

Suzy86 profile image
Suzy86

Hi! I had ICSI, 12 eggs collected and 3 fertilised which was a huge shock! I still had all 3 on day 5 had 2 transferred and I got my first ever BFP after trying for 4 and half years and this was my 4th cycle. I am now nearly 15 weeks and still can’t believe it! Have faith in your 3! I had all but given up when I was given my fertilisation results and what looked like my worst cycle yet it just happened to turn out to be my best! Xxx

LCharlton profile image
LCharlton in reply toSuzy86

That's a great story to share, thanks lovely xx

We got four eggs and only one fertilised with ICSI. We had a 2 day transfer so never even waited for a blastocyst. I've got my 12 week scan tomorrow!

Hoping all works out for you xx

LCharlton profile image
LCharlton in reply toItsalongjourney26

Great to hear! Wishing you lots of luck xx

LCharlton profile image
LCharlton

And the net result was: one of our three made it to day 5! The dr said it's a very early blastocyst. Now on board, here's hoping!!!!

NS8179 profile image
NS8179 in reply toLCharlton

Congratulations on getting this far and good luck! I am 39 (today!) and had five mature eggs of which only two fertilised and I had similar concerns as you. They both did make it to day 5 but one hadn’t become blastocyst yet and was showing signs of degeneration. Wishing you luck xxx

LCharlton profile image
LCharlton in reply toNS8179

Wishing you lots of luck too!! And happy birthday! (I'm 40, I reckon we're doing ok) xxx

Lilly12255 profile image
Lilly12255

I had zero fertilisation on my ICSI. Quite depressing. Though no male factor. I am the problem.

leo1980 profile image
leo1980 in reply toLilly12255

Try AOA on next cycle. DHEA for quality. If no male factor why ICSI? Urologist told hubby to ejaculate 24-28 hours before he produced sample for our isci. This was because damage can happen it the testes - oxidation. Just an idea

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