Hashimotos and Zoladex?: hi everyone, does... - Endometriosis UK

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Hashimotos and Zoladex?

Regenallotment profile image
2 Replies

hi everyone, does anyone have experience of taking Zoladex alongside having Hashimoto’s?

I’ve read some papers that suggest it can cause a Hashimoto’s flare and alter thyroid function.

I have fibroids and no endometriosis diagnosis, but gynae want me to have injections for 3 months to shut down ovaries and prove the pain I suffer is uterine and not endometriosis, she thinks endometriosis is a maybe 🤷🏽‍♀️. I’m not sure it’s safe for me as my thyroid can vary quite a bit and takes constant management/adjustment.

Any reassurance, experience or validation of my worries, it all seems a bit experimental and the side effects listed on the leaflet she gave me sound worse than what I’ve got 🙈

I also take cyclical urtogestan and daily estrogen gel. Age 51 with a varied regular/irregular cycle 19-54 days (28 since starting HRT)

Also posting in thyroid UK. 🙏

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Regenallotment
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AnnaMae profile image
AnnaMae

My gynae suspected hypothyroidism when I presented with some severe neuro symptoms after being on progestin for 2 years. According to test results- which I wasn't allowed to see, I was told that my parameters were not too extreme and then nothing else was said afterwards.

Regenallotment profile image
Regenallotment in reply toAnnaMae

If you are still curious you can run your own Thyroid function test for £25-40 ish depending on offers.

Random, Medichecks, Monitor my Healtth (an NHS lab) and a few others.

You would need your TSH, FT4 and FT3 and if you suspect autoimmune then TPO antibodies and ideally TgAb. Once you have the results you can post them on the Thyroid UK forum and they’ll help interpret, they’ve been so valuable to me, given me my life back.

To be considered hypothyroid you would need 2 TSH readings over range 12 weeks apart. Normal range is usually something like 0.2-4.8 but varies by lab. BUT most normal people with no symptoms have TSH around 1-2.

Once on treatment the FT4 and FT3 are the key ones, most people feel well with these about 75% through their ranges. Focusing on TSH only, it’s possible to have normal TSH and below range FTs which suggests pituitary damage. NHS don’t tell us anything about this, I’ve heard that junior GPs spend only afternoon on thyroid in training so we can forgive them knowing very little when it comes to complications with other conditions and medications.

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