Help

[Trudie22]

I'm on my second zoladex implant and hate it. It has stopped the bleeding but just near where the implant is the pain is exactly the same if not worse. I'm extremely emotional and snap all the time at my.poor partner. Hate feeling like this all the time as I'm usua so full of energy and a happy person. Is this all normal

[lucy75]

Hi Trudie

Zoladex changed my personality too and I only had the first injection. I was crying over the stupidest things, then feeling angry and feeling sick. When I went for the second one I told the nurse how I was feeling, the gp came in to see me and they both said it was extreme reaction to it and I was probably best to stop the treatment, which I did. I’m pleased with my decision, just frustrating because it clearly works for a lot of people but our bodies react differently to these drugs. Hope your soon feeling brighter.

Lucy x

[Trudie22 in reply to lucy75]

THANKYOU Lucy. Got even worse but don't wanna spk too a gp woke up this morning feeling the worse ever. Went too go too town on my day off but couldn't even make it too the bus stop

[lucy75 in reply to Trudie22]

Sorry to hear this Trudie. When are you due the next one? X

[Trudie22 in reply to lucy75]

25th of this month xx

[lucy75 in reply to Trudie22]

Ok don’t feel you have to have it. It’s your body at the end is the day. My body became so stressed a month later I developed shingles, obviously I can’t link it to this but it is related to stress. I hope you get it sorted and get help if you are struggling, even if you go to see the practice nurse. Let me know how things go. Lucy xxx

[NoEndoInSight]

Hello Trudie, really sorry that you are feeling so out of sorts at the moment.

Zoladex is a GnRH Analogue/Agonist and suppresses Endometriosis primarily by suppressing your production of oestrogen. However, oestrogen forms an integral part of many body processes and one of those is the maintainence of mood and your body’s metabolism of the “happy hormones” - dopamine and serotonin. So many women do find that drugs like Zoladex can leave them feeling agitated, angry, anxious, and depressed.

This is one of the reasons why many consultants prescribe this type of drug alongside a therapeutic dose of “addback” HRT designed to give you back enough oestrogen to avoid or minimise mood symptoms like these. It can take a bit of experimentation to find the right brand and dose of “add-back” HRT that suits you, but when you do it can really help.

Have you read the Special Product Characteristics for Zoladex? It’s the detailed advice and side effects leaflet published by the drug manufacturer? You can find it online here:

medicines.org.uk/emc/produc...

I always find it really helpful to show the drug side effects leaflet to my other half and family so they understood the impact drugs like this can have. It helps them realise that it’s not you or them causing the problem - it’s the drug that is making you feel so out of sorts. Sometimes that can really help your loved ones to understand what’s going on and allow them to better support you when you are feel like this.

I also recommend printing a copy and having it with you whenever you talk to / see you GP or Specialist as it can help you secure more effective support in dealing with any problematic side effects if you are able to say “I’m on this drug, I’ve started feeling like this, the drug SmPC leaflet suggests this is a side effect so what can you do to help me deal with it?” Sadly not all doctors are familiar with Zoladex side effects so having the SmPC to hand yourself can help avoid a lot of wasted time and confusion.

It is your Specialist and GP’s responsibility to support you through this treatment and that includes helping you deal with unpleasant side effects like fluctuating mood, so I really would recommend that you contact them ASAP about how you are feeling.

I really hope that things pick up and you are feeling more like your old self soon, x X x

[Hidden]

Hi Trudge

I have been on zoldaic and it did not suit me at all and changed me. I would go back to your doctor and discuss how you feel. Good luck. Xxx