Can Zoladex stop working?

I have just had my 5th injection of Zoladex, and over the last 2 weeks i have noticed a number of my symptoms coming back that went when i started the Zoladex. Ive started to struggle going to the toilet (have stage 4 endo on bowel), severe back ache, stomach, and arm pains. However I have not had any signs of starting my period again yet. Is it possible that the Zoladex is wearing off, or just not being effective anymore? Thanks.

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