A bit curious on how the body calculates the right amount of insulin needed. Do understand that T2 is a bit complicated with varied factors contributing, but calculating the amount of insulin needed for the digestive process seems still a Mystery. Is it the gut bacteria, or the beta cells, the liver, the pancreas or the brain?
Seems there is an underlying algorithm behind the process.
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dhini
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Sadly our body does not calculate the right amount of insulin needed , but it uses the sugar present in our blood stream with the help of insulin which is a hormone that regulates the amount of glucose in our blood.People with diabetes have problems either making insulin or how that insulin works or both. With too little insulin, the body can no longer move glucose from the blood into the cells, causing high blood glucose levels. If the glucose level is high enough, excess glucose spills into the urine. Excess insulin in the bloodstream causes cells in your body to absorb too much glucose from your blood. It also causes the liver to release less glucose. These two effects together create dangerously low glucose levels in your blood. This condition is called hypoglycemia.But in a healthy individual who is non diabetic as glucose moves inside the cells, the amount of glucose in the bloodstream returns to normal and insulin release slows down. Proteins in food and other hormones produced by the gut in response to foods like simple carbohydrates also stimulate insulin release.
Thanks osho1410 , seems what you have stated is root the cause of diabetes. Just need to focus on the line "Proteins in food and other hormones produced by the gut in response to foods like simple carbohydrates also stimulate insulin release." The release quantity or volume is calculated in a healthy body right? Not too much or too little. You are right, in a diabetic the volume may be low or the cells wont respond causing the issues. I was wondering how that calculation takes place, is it just sensing the glucose in the blood stream or some other way around? I don't think telling the beta cells to release a quantity of insulin to match the requirement is done by the pancreas alone. Correct me if aim in the wrong lane.
For a normal healthy person it's the rule of demand and supply at work rather than calculation Endocrine hormones are secreted within the tissue (rather than via a duct) and enter the blood stream via capillaries.Glands have built in feedback mechanisms that maintain a proper balance of hormones, and prevent excess hormone secretion. Low concentrations of a hormone will often trigger the gland to secrete. Once the concentrations of the hormone in the blood rise this may cause the gland to stop secreting, until once again hormone concentrations fall. This feedback mechanism (which is characteristic of most glands) causes a cycle of hormone secretions.
Once hormones have served their function on their target organs/tissues they are destroyed. They are either destroyed by the liver or the actual tissues of the target organs. They are then removed by the kidneys.
Need to learn the endocrine system as a whole. Everything is connected it seems
Was always curious to find the 'hidden thing' that triggers this whole thing.
Had read an interesting thing about the "Control Switch" in the brain that triggers diabetes. Even before reading that, this was roaming around my mind for quite some time. Again thanks for your insight, it was an eye opener.
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