Since May 2017 I have been reducing my carb intake and also doing intermittent fasting - I skip breakfast. My doctor has taken out Dibizide M from my prescription and I am now on just 250 mg metformin at night. I also do a 36 or 48 hour water fast once a week. My HbA1c has come down to 5.4 from 6.4 and my weight has reduced from 100 kgs to 85 kgs. My blood work has very good readings. My BS (mid-Jan.) FBS/PPBS is still - 126/98. For a week now I have been trying Long Wheat diet at night.
I am wondering what would happen if I stop taking metformin for a few weeks or months. Is it advisable?
First of all congratulations on your achievements, Rakins. You have achieved great numbers in particular your HbA1c of 5.4% which is in non-diabetic range.
Low carb along with intermittent fasting is really a great way to control rise in blood sugar. You should be able to come off medication after consultation with your Doctor. Members of this group can not advise on the continuation or discontinuation of medications.
It should be possible to get an idea of your insulin resistance by what is referred as HOMA IR by testing for fasting insulin and fasting glucose.
HOMA IR optimum range is between 0.5 and 1.4
> 1.9 is early insulin resistance
> 2.9 is significant insulin resistance
Regarding Metformin: Metformin has been a very well tested drug of 40 year standing without significant side effects. A small dose of Metformin should not be much of a problem if it helps you to keep the BS number acceptable level. Your final goal should be your overall blood sugar levels with or without medications.
Thanks indeed for the very useful information - let me see if this test can be done here in Kerala.
I understand that metformin is a far more benign drug than for example sulphonylurea drugs and I am glad my doctor has taken me off Dibizide M.
My doctor (of 10 years' standing) is clueless. He however took me off Dibizide M which he had prescribed five years ago. He did say that coming off metformin altogether is not medically advisable though my HbA1c has been 5.3 and 5.4 the last eight months.
I am wondering what is happening to my IR. Is it the same or has there been some improvement? The HbA1c changes could have come about through the IF and the lower carbs though I am not fully on LCHF. Is my diabetic condition still intact in spite of everything?
1) Stopping metformin requires trial and error method. You can stop but you will have to measure bs daily. If it remains under control you can omit it for ever or for a long time. But you will have to be vigilant and check your bs frequently.
2) Your ir will come down but your diabetic condition is intact .
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