Statins – Friend or Foe?

docsopinion.com/2013/01/10/...

Controversial statements in the article concerning us.

"Not giving statins to patients with documented atherosclerotic cardiovascular disease is bad clinical practice and goes against evidence based medicine....it has not been proven that statin drugs reduce mortality among healthy people with increased risk of heart disease, except for individuals with diabetes and those with the relatively rare disorder of familial hypercholesterolemia."

Now comes the controversy.

"Impaired glucose tolerance found in simvastatin treated patients is in agreement with earlier findings of impaired insulin sensitivity with statin treatment. "

A good article though.

I know many of us including myself on lchf don't take statins.

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  • All medications have side effects, and numerous studies have shown that cholesterol-lowering statin drugs are linked to a small increase in the risk of Type 2 diabetes, even as they reduce the risk of heart attacks.

    The higher the dose of a statin, the greater the diabetes risk, said Dr. Eric Topol, director of the Scripps Translational Science Institute and chief academic officer at Scripps Health.

    Source:--

    google.co.in/?gws_rd=ssl#q=...

  • gangadharan_nair

    Yes sir. But with lchf diet we can keep lipid profile under control. So can avoid statins. Also cholesterol theory has been busted by american health department. Main culprit is carbs causing inflammation in the body and cholesterol is a fireman wrongly incriminated for atherosclerosis. Cholesterol is also important for meny vital organs like brain and many hormones. It's covering of cells and nerve fibres. Lowering it can cause more harm than benefit.

    So take as less carbs as possible and enjoy statin free life.

  • My cholesterol is under limits - cardio tests are all normal- however -have a artery plaque and doctor suggested statin - to stabilize plaque - prevent future rupture.

  • champak045

    It's a myth spread by ada aha ama that statins stabilize plaque. Can you explain how?

  • NO I dont know much about Statin -- other cardiologist had suggested two years ago-But I never took statin - because that time I had high LDL.

    Do you know - how to dissolve plaque ?

  • champak045

    I am not sure but there are two types of plaques. Soft and hard. Soft in the initial stage which gets organized to become hard if the inflammatory process continues. Soft plaques can be get rid of if inflamation is checked. Can't once plaque gets organized can't be dissolved. Ask your doctor how statins stabilize the clot 🐒💭

  • yes -I know about soft and hard - calcified fat ( protein) - is hard

    I am concern about soft becoming loose and becoming a clot -

    which can be more dangerous - can cause stroke. That's why stabilization is important. Inflammation --my Hs Crp was normal - I had done blood test as part of Cardio IQ tests - hs crp - high sensitivity CRP

  • champak045

    The question is how statins can stabilize clots. It's a rumor mispropaganda spread to sell statins. The fact of the matter is no medication can stabilize an atheroma. Only ongoing inflammation brings fibroblasts, platelets and ultimately calcium to seal the inflammation site. That will fix the atheromatous plaque and not any medication. But we don't want an atheroma to form and get fixed because that will narrow the arteries permanently. Vessel blockade.

  • I don't understand this ...never seen this info.

    Usually plaque- is 20 % calcium and 80 % fat.

    I have info from Cardiologist who has performed over 2000 heart surgery. He recommends supplements - for artery repair.

    I take Vitamin K ( Mk-7), L-arginine, Aged Garlic with CoQ10 and Pycnogenol

    will do another Calcium Score test to see if it reduced.

  • champak045

    Ask him how statins stabilise plaques if 80% fats. Statins according to them reduce cholesterol - fats. So less fat will destabilize the plaques. Organised plaques mainly fibrous and muscle tissues plus intimal - endothelual debris. Fats also. % i'm not sure but i'd love to know about the statin claim.

    "The accumulation (swelling) is always in the tunica intima, between the endothelium lining and the smooth muscle middle layer of the artery wall. While the early stages, based on gross appearance, have traditionally been termed fatty streaks by pathologists, they are not composed of fat cells but of accumulations of white blood cells, especially macrophages, that have taken up oxidized low-density lipoprotein (LDL). After they accumulate large amounts of cytoplasmic membranes (with associated high cholesterol content) they are called foam cells. When foam cells die, their contents are released, which attracts more macrophages and creates an extracellular lipid core near the center to inner surface of each atherosclerotic plaque. Conversely, the outer, older portions of the plaque become more calcified, less metabolically active and more physically stiff over time."

  • Is there any effect taking statin for choloestrol?

  • dwarakanath

    Aha has removed cholesterol from the list of notorious substance.

    google.co.in/url?sa=t&sourc...

  • yes-it does reduce cholesterol.

    However - I like natural remedy.

  • Surprised-- just got results today. My Total Cholesterol is only 114 ( down from 148 -three months ago ). My TG - 82, HDL - 43 and LDL - 55 ( down from 90 ).

    I am NOT sure how or why. I have NOT taken any statin medicine. Just started on a few days ago for my plaque.

    May be side effects of Glipizide?

  • champak045

    What's your a1c

  • on May 03, --it was 6.2 - Then doctor told me to stop taking second medicine Glipizide-- after two months - I was checking at random - and it was high - so I informed doctcor and start taking Glipizide again.

    Just gave blood yesterday- will have new A1C --soon in few days.

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