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Clinical evaluation of the hepatoprotective effect of Katuki (Picrorhiza kurroa )

nopr.niscair.res.in/bitstre...

The hypolipidaemic drugs have attracted considerable attention because of their potential to prevent cardiovascular disease by retarding the accelerated atherosclerosis in hyperlipidaemic individuals. Statins are the first choice drugs for primary hyperlipidaemias with raised LDL and total cholesterol levels, with or without raised triglycerides levels, as well as for secondary hypercholesterolemia. Statin therapy is commonly associated with liver damage in terms of elevated aminotransaminases...................

................ Statins therapy was associated with liver damage in terms of markers of hepatotoxicity, i.e. elevation in serum bilirubin, AST (SGOT), ALT (SGPT), and serum alkaline phosphatase, but the clinically significant hepatotoxicity caused by statins remained absent.Katuki (Picrorhiza kurroa Royle ex Benth.) processed in Guduchi (Tinospora cordifolia ) have proved to be effective Hepatoprotective drug as both components have not produced statistically

significant hepatotoxicity, i.e. elevation in serum bilirubin, AST (SGOT), ALT (SGPT) and serum alkaline phosphatase in the patients registered for the current trial. Thus, it can be concluded that Katuki (Picrorhiza kurroa Royle ex Benth.)processed in Guduchi (Tinospora cordifolia)

are effective drugs in checking the progress of the drug induced hepatitis

especially by statins.

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The opening statement implies that high cholesterol levels cause heart disease. Dr Malcolm Kendrick refutes this, stating that Irribarren's hypothesis has been disproved time and again, yet is still widely used by the medical profession.

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Concerned topic is all about statin....and liver damage.... if cholesterol is problem or not is debatable...

Ok....I agree lol...cholesterol is most important for body functions.....

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Not having too much fructose or alcohol is hepatoprotective authoritynutrition.com/suga... ;-)

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agreed Concerned they say fructose is more harmful than alcohol....

Once you get diagnosed with NAFLD .....and diabetes....and when docs put you on statin(its standard protocol they say) you have perfect recipe to get your liver damage....and remain diabetic for life time....

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It'll be interesting to see how they differentiate between the harm done by statins and the harm done by lowering cholesterol.

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drbriffa.com/2012/12/07/fib... Don't they still give fibrates along with statins and when the side-effects of statins are too severe?

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Bhai log....are we diverting???? This url is about usefulness of Kutki....

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