A drug used to induce labor in pregnant women has been shown to reactivate tiny waste-clearing pumps in the brains of old mice. The finding could hold promise as a new way to fight Alzheimer's and Parkinson's diseases and overall cognitive decline. newatlas.com/health-wellbei...
Prostaglandin F2alpha en.wikipedia.org/wiki/Prost...
Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury ncbi.nlm.nih.gov/pmc/articl...
Study here: nature.com/articles/s43587-...
This is of interest because the microglia clean up excess alpha synuclein In the intercellular space. A mutation known to interfere with this process causes Parkinson's. So better circulation of the CSF might be helpful to reduce that load.
A few years back I read several books about Energy Medicine. In each of the books, one of the things you could do was the following: spread the fingers and thumb out wide on one hand. With the other hand massage, the area between the thumb and pointer finger. Don't just be on the outermost part of the web that is only skin, but where you can feel the muscles and tissues. Repeat for the other hand.
In each book when they described the above massage, they warned to NOT do this if you are pregnant because it might bring on premature labor. So, maybe this is a drug free way that we can improve the drainage of dirty CSF starting today!
And that is also how you get rid of headaches ... hmmmm. Feels good to do it too, like the good pain from a massage. Gonna do this more often now. Thank you.
Thanks you, for whats time? Excuse me, my english is terrible
I didn't remember how long to do this. The following excerpt is from the link that NiccNZ included below. Based on what it says, considering we have a chronic condition, I would think we should be doing it for several minutes, repeating several times throughout the day. Also note that the link said that this point is good for addressing constipation.
This point is usually a little achy (especially when it needs some love!), which can help us know when we’ve found just the right spot. Once you find the spot you can massage it with gentle to moderate pressure in small circular motion for several minutes. Acupressure usually works pretty quickly, so you should feel some relief within the first few minutes. If you are massaging LI4 for a migraine or acute sinus pain, you will likely need to repeat this massage throughout the day if the pain returns. This is also an awesome point to stimulate to help ease and regulate bowel movements, and can be incorporated as part of your daily routine, anytime you are on the “throne”!
Very interesting, thank you!
A little bit more about this useful acupressure point:
Further Searching:
😮❗Systemic adverse reactions to prostaglandin F2 (PGF2 alpha, dinoprostone, prostin F2 alpha, prostalmon F): pubmed.ncbi.nlm.nih.gov/696....
"Prostaglandins are mainly used in clinical medicine for midterm abortion and to terminate pregnancy. Systemic adverse reactions include nausea and vomiting, which occur in approximately half of the patients and, to a lesser extent, diarrhea. Although bronchospasm occurs infrequently, PGF2 should be avoided in asthmatics. Cardiorespiratory failure culminating in prolonged coma and death has been reported. Moreover, convulsions and EEG changes have been observed in a comparatively small number of cases."
Where applied? Maybe eyes, which has the optic nerve for assess to brain.
I can only access an Abstract to the linked article. nature.com/articles/s43587-...
The Abstract says nothing about dose, but does say topical application, Makes me wonder where applied and if maybe eye drops for glaucoma was used (Latanoprost). Latanoprost is an prostaglandin F2 alpha analog. ncbi.nlm.nih.gov/books/NBK5...
park_bear Do you have assess to more than the Abstract?
The Nature article abstract that Park Bear linked to says to apply to the cervical lymphatic vessels. You can see below the location of the cervical lymphatic vessels in the picture, as well as more info in the paragraph. The link is the source for the picture/description.
teachmeanatomy.info/neck/ve....
• Superficial Cervical: The superficial cervical lymph nodes can be divided into the superficial anterior cervical nodes and the posterior lateral superficial cervical lymph nodes. The anterior nodes lie close to the anterior jugular vein and collect lymph from the superficial surfaces of the anterior neck. The posterior lateral nodes lie close to the external jugular vein and collect lymph from superficial surfaces of the neck.
NextStage
My question: Do you have assess to more than the Abstract? was meant for nature.com/articles/s43587-...
I can only read the Abstract and was wondering if park_bear had assess to the whole article.
No I did not have access to more than the abstract. There's a bit more available here - the first page: researchgate.net/publicatio...
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