'Reverse Parkinson' by breathing-in Farnesol with a humidifier?

[PDWarrior1900]

"Farnesol, a natural compound of some herbs and fruits in commercial use, was seen to protect nerve cells in the brain and possibly restore some of these cells to health in multiple mouse models of Parkinson’s disease."

“Our experiments showed that farnesol both significantly prevented the loss of dopamine neurons and reversed behavioral deficits in mice, indicating its promise as a potential drug treatment to prevent Parkinson’s disease,” Ted Dawson, MD, PhD, director of the Johns Hopkins Institute for Cell Engineering and one of the study’s lead authors, said in a press release."

The information above is from this first, 2021 research article.

parkinsonsnewstoday.com/new...

genengnews.com/news/parkins...

cureparkinsons.org.uk/2021/...

pubmed.ncbi.nlm.nih.gov/263...

medicalnewstoday.com/articl...

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This M.D. eye doctor highly recommends a humidifier if you have dry eyes (I do) -- which is a common symptom on PWP, as you know.

youtu.be/kE9xFFVCUV8(Not working as expected?)

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I just found this great deal with an Amazon/ Alexa voice controlled humidifier!

I can hardly wait for delivery and add the farnesol that I bought.

I just searched Google for 'where' I bought it but I can't find the essential oil anywhere!

I'll update this post if I find it. But farnesol is also found in: citronella, lemongrass, and balsam.

[PDWarrior1900]

I found the link/ source to buy farnesol on Amazon

amazon.com/gp/product/B07DV...

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farnesol

[Gcf51 in reply to PDWarrior1900]

A few years ago, I searched for farnesol. I brought some and the bottle listed ingredients indicated more preservative than farnesol. I wonder how much preservative is in this.

[PDWarrior1900 in reply to Gcf51]

wow -- your reply was a real EYE OPENER for me! I have a bottle of this stuff right in front of me that I have used several times in my diffuser. So to reply to your question I just grabbed the bottle and read the 'WARNING LABEL' on the back which specifically tells me NOT to use it the way I've been using it!!! It's so bad that now I have to call the company to make further inquiries as I thought this was a very safe to use essential oil. I'll update here later... and thanks again!

[Gcf51 in reply to PDWarrior1900]

Hope you find OK to use the way you where.

[PDWarrior1900 in reply to Gcf51]

i'll update as soon as i call the company -- my guess is that they will tell me not to use it in its 'pure form' -- but only as an ingredient along with others

[PDWarrior1900 in reply to Gcf51]

you'll find the product (which I bought on Amazon) source here:

consolidated-chemical.com/F...

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it specifically reads this on the label:

Farnesol Fragrance/Aroma Compound

Packaged in Glass Bottle

30mL (1 fl oz)

Fragrance/ Aroma Compound

Product description

Odor Description: A delicate, fresh, green muguet note.

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So now I am REALLY CONFUSED about their 'warning label' on the back of the bottle

[guitar-player in reply to PDWarrior1900]

In Canada, farnesol is classified as a natural health product and is regulated by Health Canada. In Australia, it is classified as a complementary medicine and is regulated by the Therapeutic Goods Administration (TGA).

[Bozo123]

eager to hear what you find out!

[Raimo]

If you opt to go with a cool mist humidifier, be sure to use distilled water. I noticed an oddity last year when I was using a cool mist humidifier with tap water. The flame on the gas range would be yellow and orange instead of blue all day following overnight use. The humidifier was running upstairs in the bedroom well away from the kitchen. A quick search revealed the cause. The cool mist units expel all the minerals in the water into the air and react with the flame. Due to our likely sensitivity to minerals, e.g. manganese, it's best to avoid this. Rather than deal with the recurring cost of distilled water, I decided to go with a warm mist humidifier. I'm very satisfied with my new unit, and my gas range burns blue again.

One crazy thought. If it proves to be safe to breathe the farnesol oil, you could always try using a plug-in air freshener. I pop the cap off emptied refills, put Lavendar oil in them, and snap the cap back on.

[PDWarrior1900 in reply to Raimo]

excellent reply, thanks! and I literally... moments ago... tried to call this "company"

with this website which lists dozens of products...

consolidated-chemical.com/

their phone number is: [phone]

BUT... it was an answering machine with 'no' greeting!

something does NOT add up here

[PDWarrior1900 in reply to Raimo]

i never heard of a humidifier being described as "cool" or "warm" mist... i have to research this... thanks

[PDWarrior1900 in reply to Raimo]

you're a smart person! just confirmed all your good advice here:

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mayoclinic.org/diseases-con...

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"If you use a humidifier, be sure to keep it clean to prevent mineral buildup and the growth of bacteria and molds. Humidifiers that hold standing water, particularly cool-mist humidifiers, can disperse these materials into the air. Warm-mist humidifiers generally disperse less, if any, of these materials into the air."

"Emptying the tank and drying all surfaces of the humidifier daily is one way to safely keep it clean. Also, consider refilling the tank with bottled water labeled "distilled" or "purified," which has a lower mineral content than most tap water."

[PDWarrior1900 in reply to Raimo]

just wanted to confirm something with you since you just saved my health (I just canceled my Amazon delivery of a "cool mist" humidifier ... My other post had advice from mayo clinic about humidifiers and recommended "distilled" water (which gets pretty expensive if I'm using this humidifier daily) .... You said that with your "warm mist" humidifier you use "tap" water... is that correct? and you feel OK with that if you do?

[Raimo in reply to PDWarrior1900]

Yes, I use tap water in my warm mist humidifier and feel confident it's not dispersing impurities into the air. It still needs cleaning every 4-5 days to remove residue.

This is the one I purchased. Unfortunately, it's currently out of stock. It does have a tray for essential oils.

amazon.com/gp/product/B08G1...

[PDWarrior1900 in reply to Raimo]

thanks very much (cough! cough!) for the reply... LOL ... you really saved me, pal!

[PDWarrior1900]

This company's phone number is a 'voicemail with no greeting' .... weird...

so i just emailed them... I'll report back here once I've heard from them

[PDWarrior1900]

11.28.22 -- I just spent a couple of hours online and I called '2' companies that sell Farnesol. Neither of them recommended Farnesol for therapeutic use -- but only for commercial or industrial application. I'm very confused because I bought a bottle of this stuff at.... Amazon! .... And I have used it at least a dozen times without suffering any ill (or 'PD helpful') effects. But for now, I'll err on the 'safe side' and not use it anymore. Too bad... because simply "breathing in" a remedy is so appealing to all of us... Another 'rabbit hole'... i guess...

[limcheeese22]

believe me or not, I even drink a few bottle mixed with water. i bought it here: naturallythinking.com/farnesol,, no significant effect, then I stopped. i think breathing-in is fine. will try, I still have 2 bottles 50ml..

[PDWarrior1900 in reply to limcheeese22]

well... if you read my post... today i spoke to two manufacturers of farnesol and both said a resound 'No!' to anything except commercial and industrial use of farnesol

[Gcf51]

FYI - doTerra via email said: (approximately 1 yr ago.)

Thank you for your question! Farnesol is a group of sesquiterpene alcohol isomers—(E,E)-farnesol, (E,Z)-farnesol, (E)-beta-farnesol—that may be found in some essential oils like sandalwood (Santalum spicatum), neroli, niaouli, cananga, rose, yarrow, and magnolia. When it is present, it is typically found in lower amounts. It may be present in the aforementioned doTERRA essential oils.

[PDWarrior1900 in reply to Gcf51]

thanks

yesterday was sad... i called two manufacturers of farnesol and both said NOT to use it therapeutically (not in my diffuser or humidifier)

[PDWarrior1900]

I just found this great link about farnesol.

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fragranceconservatory.com/i...

[PDWarrior1900]

Here's another great link about farnesol as a treatment for PD!

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cureparkinsons.org.uk/2021/...

[PDWarrior1900]

Here's ANOTHER great great great article about Farnesol's use to treat PD!

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content.iospress.com/articl...

[PDWarrior1900]

I just got this email reply from a well-know company that manufactures high quality essential oils:

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Hello,

Thank you for your question! Farnesol is a group of sesquiterpene alcohol isomers—(E,E)-farnesol, (E,Z)-farnesol, (E)-beta-farnesol—that may be found in some essential oils like sandalwood (Santalum spicatum), neroli, niaouli, cananga, rose, yarrow, and magnolia. When it is present, it is typically found in lower amounts. It may be present in the aforementioned doTERRA essential oils.

Please let us know if we can help you with anything else.

Sincerely,

dōTERRA Product Support

[e-mail]

[Ghmac]

I have read a lot about Farnesol in the past. My only question is its affect on dogs. Some EO can be very harmful to dogs.

[Ghmac in reply to Ghmac]

Both Lemongrass and lavender are harmful to dogs.

[Thaxter]

I looked up natural sources and saw this link:

researchgate.net/figure/Var...

I'm using pure lemongrass oil in my diffuser.

[Comeon77 in reply to Thaxter]

Hey how is it going any improvements

[Thaxter in reply to Comeon77]

Honestly, I don't use my humidifer enough to comment! I am also using Vertiver, as it has been shown to help ADHD.

[PDWarrior1900]

excellent post, i'll research this more... thanks and Merry Christmas!

[Comeon77 in reply to PDWarrior1900]

Hello there do you have parkinson's if you do did you try farnesol i want to know if it had an effect of parkinson's in humans

[PDWarrior1900 in reply to Comeon77]

i'm not officially dx'd ... my neuro/MDS is a big dummy ... i have multiple "parkinson-like" symptoms (internal tremors, vision / eyelid tremors, left face numbing, constipation, feet and lower leg cramps) ... NONE (thank God) ... except for the constipation which I think I finally have under control ... are affecting my life... and ... they are not getting worse... my first symptom started on June 20, 2021 with my left thumb visibly tremoring for a few seconds ...

now ... i rarely, rarely, have any limb movement ... I'm taking about 40 supplements daily and i'm on an O.M.A.D. diet -- today is day #386! ... (one meal a deal with all calories eaten within a 2 hour window). I ignored the doctor's request for a DatScan and blood work because he completely ignored MY mountains of data that I had prepared for him (also a 2 page summary). ... So as for 'farnesol' ... i gave up on that when I heard about the negative effects from the companies that SOLD it. It is for 'perfume products'.... NOT... for PD therapy... Best of luck to you

[roller2]

I was interested in your discussion on using Farnesol in a humidifier and thought it might be possible to get Farnesol in vape form. I came up with this article about Farnesol (Green Apple Flavour) being used to stimulate reward behavior in vape users. It states:

"Our electrophysiological assays with male mice revealed that farnesol treatment increases ventral tegmental area (VTA) dopamine neuron firing frequency and this may be due to a decrease in inhibitory tone from GABA neurons"

pubmed.ncbi.nlm.nih.gov/313...

I’m not sure if this can be of any benefit to alleviate the symptoms of Parkinsons but I thought I would throw it in as an aside to your discussion.

[PDWarrior1900 in reply to roller2]

thank you for the good post... all information is welcome here

[Router_]

dergipark.org.tr/en/pub/huj...

University paper, but hey - at least another positive hint

[PDWarrior1900]

thanks .... but .... 'flies'???

[Router_]

😀 Gotta start somewhere right