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Could the “little blue pill” help in more ways than one??? Might be fun trying to find out!!! lol

https://www.google.com/amp/s/newsroom.clevelandclinic.org/2021/12/06/cleveland-clinic-research-identifies-sildenafil-as-candidate-drug-for-alzheimers-disease/amp/
https://www.google.com/amp/s/newsroom.clevelandclinic.org/2021/12/06/cleveland-clinic-research-identifies-sildenafil-as-candidate-drug-for-alzheimers-disease/amp/
redhawk1 profile image
redhawk1
in Cure Parkinson's

Reduced risk of Alzheimers disease in 15,820 people with T2D randomized to GLP-1R agonists in clinical trials and in Danish registry

Reduced risk of incident #Alzheimers disease in 15,820 people with #T2D randomized to GLP-1R agonists in clinical trials and in Danish registry data https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12268
Reduced risk of incident #Alzheimers disease in 15,820 people with #T2D randomized to GLP-1R agonists in clinical trials and in Danish registry data https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12268
nedim profile image
nedim
in Cure Parkinson's

L-Serine, safe & shows promise in reducing PD, ALS, ALZ. PD trial. Will be culminating research below.

https://fortune.com/longform/alzheimers-disease-cure-breakthrough/amp/
https://fortune.com/longform/alzheimers-disease-cure-breakthrough/amp/
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NeuroResearcher
in Cure Parkinson's
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Is Viagra neuroprotective

A 2021 study suggests that sildenafil (Viagra, Revatio), which is used to treat erectile dysfunction and pulmonary arterial hypertension, might also protect against Alzheimers disease: https://www.health.harvard.edu/mens-health/erectile-dysfunction-drug-may-lower-alzheimers-risk?
A 2021 study suggests that sildenafil (Viagra, Revatio), which is used to treat erectile dysfunction and pulmonary arterial hypertension, might also protect against Alzheimers disease: https://www.health.harvard.edu/mens-health/erectile-dysfunction-drug-may-lower-alzheimers-risk?
Farooqji profile image
Farooqji
in Cure Parkinson's

Is Alzheimer’s Disease a Liver Disease of the Brain? 2020

Is Alzheimer’s Disease a Liver Disease of the Brain? 2020 https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190848 If Alzheimer’s Disease can be caused by the liver, well maybe PD can too.
Is Alzheimer’s Disease a Liver Disease of the Brain? 2020 https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190848 If Alzheimer’s Disease can be caused by the liver, well maybe PD can too.
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

My ex-boss spotted a positive article on Hyperbaric Oxygen. Any idea if this would benefit Parkinsons?

The article is: https://www.aftau.org/news_item/hyperbaric-oxygen-therapy-reverses-hallmarks-of-alzheimers-disease-and-dementia/ This is the full strength version of the article: https://www.aging-us.com/article/203485 Appreciate feedback from the wonderful members of this amazing group.
The article is: https://www.aftau.org/news_item/hyperbaric-oxygen-therapy-reverses-hallmarks-of-alzheimers-disease-and-dementia/ This is the full strength version of the article: https://www.aging-us.com/article/203485 Appreciate feedback from the wonderful members of this amazing group.
pmmargo profile image
pmmargo
in Cure Parkinson's

Simon's post and thiamine HCL.

https://scienceofparkinsons.com/2022/04/13/b1/ Please excuse if it's been already posted. Also talks about Alzheimer's, benfotiamine. Interesting.
https://scienceofparkinsons.com/2022/04/13/b1/ Please excuse if it's been already posted. Also talks about Alzheimer's, benfotiamine. Interesting.
parkie13 profile image
parkie13
in Cure Parkinson's

GV-971 For Alzheimer's Disease Now and PD Later This Year

Although this study is about Alzheimer's Disease (AD), it is very interesting in showing how the gut microbiota can be manipulated to very good effect and that fact is very important for many diseases including PD. It is also worth noting that some of the methods of action that have so far been discovered
Although this study is about Alzheimer's Disease (AD), it is very interesting in showing how the gut microbiota can be manipulated to very good effect and that fact is very important for many diseases including PD. It is also worth noting that some of the methods of action that have so far been discovered
chartist profile image
chartist
in Cure Parkinson's

L-Tryptophan, it should be in your stack (Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond)

L-Tryptophan metabolism through the kynurenine pathway is involved in the regulation of immunity, neuronal function and intestinal homeostasis. Imbalances in tryptophan metabolism in disorders ranging from cancer to neurodegenerative disease have stimulated interest in therapeutically targeting the kynurenine
L-Tryptophan metabolism through the kynurenine pathway is involved in the regulation of immunity, neuronal function and intestinal homeostasis. Imbalances in tryptophan metabolism in disorders ranging from cancer to neurodegenerative disease have stimulated interest in therapeutically targeting the kynurenine
SilentEchoes profile image
SilentEchoes
in Cure Parkinson's

What is AMX0035, and Why Is It Important for All of Us?

AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
SilentEchoes profile image
SilentEchoes
in Cure Parkinson's

Is anyone here boosting their plasmalogen levels?

I've watched several interviews with biochemist Dayan Goodenowe PhD (https://drgoodenowe.com/) where he discussed increasing plasmalogen levels to prevent Alzheimer's and other dementias. He mentioned that higher plasmalogen levels also help in Parkinson's by improving function in dopaminergic neurons
I've watched several interviews with biochemist Dayan Goodenowe PhD (https://drgoodenowe.com/) where he discussed increasing plasmalogen levels to prevent Alzheimer's and other dementias. He mentioned that higher plasmalogen levels also help in Parkinson's by improving function in dopaminergic neurons
genesurf profile image
genesurf
in Cure Parkinson's

ANNOVIS BIO ANNOUNCES POSITIVE FDA FEEDBACK FOR BUNTANETAP PHASE 3 CLINICAL DEVELOPMENT IN PARKINSON'S DISEASE (ANVS401)

https://irpages2.eqs.com/websites/annovis/English/431010/us-press-release.html?releaseID=111474&d=202201250900 The U.S. Food and Drug Administration (FDA) has given positive feedback to Annovis Bio’s plans to start two Phase 3 clinical trials of buntanetap (ANVS401) as an oral therapy for early- and
https://irpages2.eqs.com/websites/annovis/English/431010/us-press-release.html?releaseID=111474&d=202201250900 The U.S. Food and Drug Administration (FDA) has given positive feedback to Annovis Bio’s plans to start two Phase 3 clinical trials of buntanetap (ANVS401) as an oral therapy for early- and
nedim profile image
nedim
in Cure Parkinson's

The Potential Utility of Prebiotics to Modulate Alzheimer’s Disease: A Review of the Evidence

The Potential Utility of Prebiotics to Modulate Alzheimer’s Disease: A Review of the Evidence 2021 https://www.mdpi.com/2076-2607/9/11/2310/htm 6. Concluding Remarks Although human clinical studies examining the effects of specific prebiotics on gut microbiome-mediated cognitive health outcomes in AD
The Potential Utility of Prebiotics to Modulate Alzheimer’s Disease: A Review of the Evidence 2021 https://www.mdpi.com/2076-2607/9/11/2310/htm 6. Concluding Remarks Although human clinical studies examining the effects of specific prebiotics on gut microbiome-mediated cognitive health outcomes in AD
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

Vascular Dysfunction in the Brain as an Initiating Event in Parkinson’s Disease

https://parkinsonsnewstoday.com/forums/forums/reply/20641/ The concept that Parkinson’s disease is essentially a vascular dysfunction disorder comes from the pioneering work of Dr. Berislav Zlokovic and his research team at the Keck School of Medicine at the University of Southern California. These USC
https://parkinsonsnewstoday.com/forums/forums/reply/20641/ The concept that Parkinson’s disease is essentially a vascular dysfunction disorder comes from the pioneering work of Dr. Berislav Zlokovic and his research team at the Keck School of Medicine at the University of Southern California. These USC
JayPwP profile image
JayPwP
in Cure Parkinson's

Shining a light on Protein Aggregation in Parkinson's Disease

You don't need a niacin prescription either. https://www.mdlinx.com/news/researchers-discover-intake-of-fda-approved-drug-modulates-disease-progression-in-alzheimers-disease/76FINpPCpzJfueriPH2eRN?
You don't need a niacin prescription either. https://www.mdlinx.com/news/researchers-discover-intake-of-fda-approved-drug-modulates-disease-progression-in-alzheimers-disease/76FINpPCpzJfueriPH2eRN?
SilentEchoes profile image
SilentEchoes
in Cure Parkinson's

MIND diet associated with better cognitive functioning in elderly

https://medicaldialogues.in/amp/neurology-neurosurgery/news/mind-diet-associated-with-better-cognitive-functioning-in-elderly-study-82227 Aging takes a toll on the body and on the mind. The neurodegeneration menifests in form of tissue of aging human brains sometimes developing abnormal clumps of proteins
https://medicaldialogues.in/amp/neurology-neurosurgery/news/mind-diet-associated-with-better-cognitive-functioning-in-elderly-study-82227 Aging takes a toll on the body and on the mind. The neurodegeneration menifests in form of tissue of aging human brains sometimes developing abnormal clumps of proteins
JayPwP profile image
JayPwP
in Cure Parkinson's

Interesting Methylene Blue Dosing Story

There is a whole lot more information in this 2018 paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734125/ Here is one more amazing story about LMTM: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad210390
There is a whole lot more information in this 2018 paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734125/ Here is one more amazing story about LMTM: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad210390
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

I'm going to test Dr. Bredesen's theories on myself. Anyone else interested? Here's a brief introduction:

I'm excited by the results being reported by Bredesen and other doctors he's trained. Results mean a LOT when it comes to complex brain disfunction (such as Parkinson's and Alzheimer's), and he's getting them! My goal here is to start a discussion, explore what he's doing in his "protocol", and how
I'm excited by the results being reported by Bredesen and other doctors he's trained. Results mean a LOT when it comes to complex brain disfunction (such as Parkinson's and Alzheimer's), and he's getting them! My goal here is to start a discussion, explore what he's doing in his "protocol", and how
JAS9 profile image
JAS9
in Cure Parkinson's

Ginkgo Biloba - Bacopa Monnieri (Brahmi) - Vinpocetine Combo

Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116202/ Neuroregulatory role of ginkgolides: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338821/ Vinpocetine Biloba Stack: https://www.braintropic.com/nootropics/vinpocetine
Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116202/ Neuroregulatory role of ginkgolides: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338821/ Vinpocetine Biloba Stack: https://www.braintropic.com/nootropics/vinpocetine
JayPwP profile image
JayPwP
in Cure Parkinson's

COVID-19 Tied to Acceleration of Alzheimer's Pathology, Parkinson's as well?

A very interesting and well done study out of NYU. While focusing on ALZ, it obviously has ramifications across all neurodegenerative diseases, such as PD. In many respects this answers the question that many PwP had regarding infection from Covid-19 or its variants. COVID-19 Infection Associated with
A very interesting and well done study out of NYU. While focusing on ALZ, it obviously has ramifications across all neurodegenerative diseases, such as PD. In many respects this answers the question that many PwP had regarding infection from Covid-19 or its variants. COVID-19 Infection Associated with
sharoncrayn profile image
sharoncrayn
in Cure Parkinson's
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