I initially started taking B1 HCL orally, on the magical quest to find my optimal level, which I failed to do over a year and a half. I came to the conclusion that since I was often more or less constipated, as many Parkinsonians are, I would never be able to find that level, as it varied based upon how constipated I was. So I decided to try sublingual B1.
However, I was recently informed that B1 100 mg Sublingual tablets do not exist, but that B1 tablets described as "microlingual" or "easy melting" do. I'm assuming that those who claim success using "sublinguals" actually mean one of those.
A couple of questions :
- I've noticed that these "easy melting" pills do melt easily, but they're not quickly absorbed from under the tongue. They mix with saliva and the B1 in the solution is very gradually absorbed over at least an hour. It's my understanding that Thiamine Mononitrate, which is used in these tablets, can be bad for the digestive system. So does that mean that I shouldn't swallow what is left of the weakened Thiamine Mononitrate /Saliva solution?
- Since Thiamine Mononitrate is potentially toxic, why not simply use Thiamine HCL 100 mg pills, since the remaining solution containing the B1 HCL can be swallowed since it's harmless to the digestive system? There's no need to spit the remainder out. Dissolving the gelatin casing of these pills adds a bit of time, but the absorption rate is the same as it is for the mononitrate.
Thanks.
Cocarboxylase form of b1 -- would this be okay to use?
Critique My Supplement Stacking? Share Your Protocol?
Mucuna Pruriens and B1 capsules 
Vitamin B1 & Parkinson’s 
It seems that there’s a lot of misinformation out there about microlingual vs. sublingual B1, with much of the confusion originating from the Facebook group ‘Parkinson’s Thiamine HCl’. The administrator of the group is a former member of this forum. Unfortunately he is dispersing inconsistent, confusing and in some cases completely incorrect information about the B1 protocol. Myself and others have tried to correct him on his errors, but he won’t listen and bans any users who disagree with him from that group.
Do yourself a favor and join the Facebook group called ‘Parkinson’s B1 Therapy’. It is run by Daphne (also a member of this group) who has written an excellent book about the B1 protocol which is available on Amazon. Her Facebook group has a much more helpful tone, but more importantly the information being discussed on that group is much more accurate.
Thanks for the reference to Daphne's Facebook group. I just applied to join.
I am not a member of either group nor have i read the book. But i do wonder what you make of Fotoworkz' post below?
hi there. I went back to Dr Constantine’s original recommendations and on the number of people he treated , decided that it was the route to follow. I then researched more on B1 andcame across Dr Longsdale. Much inf to get my brain around.
Derrick Lonsdale
pubmed.ncbi.nlm.nih.gov/346...
Quote: “This suggests that the RDA requirement may be insufficient to meet the demands of modern living. Inasmuch as thiamine deficiency syndromes pose great risk of chronic morbidity, and if left untreated, mortality, a more comprehensive understanding of thiamine chemistry, relative to energy production, modern living, and disease, may prove useful.”
In my experience this energetic effect is mainly experienced at a cerebral rather than a physical level, i.e. with greater attention and recall efficiency which are skills more useful to students than to a PwP. This lasts a few hours but this gives an idea of what thiamin can do to brain cells acutely and can be a test. A restorative effect as defined by Dr C.
Greetings from Italy
Gio