Body odor from thiamine hydrochloride?

[Mimer]

Hi,

I am newly diagnosed with PD and have not started with any medication yet. But I take a daily "coctail" of:

B1 Thiamine hydrochloride powder 2 ml (close to 1 g)

NAC powder 1,5 g

l-citrulline 1 g

Glutathione 200 mg

Mannitol 4 ml

Creatine occationally

My spouse is complaining about my new body odor. I think it comes from B1 thiamine? Anyone else that have noticed that? Is it better to take pills than a water powder solution? Or is there anything else you could do to minimize the odor?

I have to admit that I was a little bit skeptical to trying B1. But I have a lot of non-motor symptoms and thinks it helps quite well so far to alleviate those. Still trying to find optimal dosage though. My motor symptoms are mostly bradykinesia and stiffness on the left side of my body.

[park_bear]

I take B1 and NAC not aware of any change in body odor. However, I have noticed that the B1 seems to be a good mosquito repellent, so there is something that different that they notice or no longer notice.

[chartist in reply to park_bear]

park_bear,

I did notice when I was experimenting with higher dose NAC that it made my urine smell a bit like sulfur.

Art

[Mimer in reply to chartist]

Would you consider 1.5 g per day as a high dose? My weight is around 78 Kg with normal BMI.

[chartist in reply to Mimer]

Mimer,

For me it was an experiment where I was escalating my dose until at a dose of 2.4 grams, my stomach couldn't take it any more, so I don't really know what would be the best dose for you, sorry. I can say that at any of the doses I tried, I never noticed any difference from what I would consider my norm except for the gastro issue.

Art

[rescuema]

Exercising and sauna detox might help. If you have constipation, that could be another contributor.

Listen to this podcast.

npr.org/transcripts/817977005

[Mimer in reply to rescuema]

Thanks for the tip. I do daily excersise, but will try to drink more water during the day. Sauna is hard to do now due to the covid-19 situation.

[parkie13]

No body odor from thiamine HCL. If the odor is a musty smell, on this list few people have mentioned it that the parkie's have a musty smell and their Partners can smell it.

[Jjm0zx in reply to parkie13]

The smell from PD people can be detected by people with hypersensitive smell. it is musty or as my wife would say smells like old gym clothes at times. More frequent showers and deodorant.

[Astra7]

I think it’s just another sympton from the gift that keeps on giving!

My husband complains that I smell different - he thinks it’s a diabetic type thing.

I don’t take B1 though.

[LAJ12345]

It may be the actual condition rather than the supplements.

[Mimer]

Thanks for all replies. As you say, it could very well also be a symptom of PD. The reason for suspecting B1 is that the powder I bought smells.