Report: Ceylon Cinnamon Relieves Parkinso... - Cure Parkinson's

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Report: Ceylon Cinnamon Relieves Parkinson's Motor Impairment. Evidence Suggests Remedy of Underlying Disease

park_bear profile image
park_bear

This post includes both personal observation and evidence from the medical literature.

Using The Correct Cinnamon:

There are two varieties of cinnamon. One is Ceylon cinnamon, also known as cinnamomum verum or cinnamomum zeylanicum, which has an acceptable safety profile. The other variety of cinnamon, cassia cinnamon, contains coumarin, a blood thinner. It is also called cinnamomum aromaticum, and is grown in Southeast Asia. It should not be consumed in quantity. Ceylon cinnamon is readily available at Amazon and elsewhere. It is milder than cassia cinnamon, which makes it easier to ingest in quantity. In what follows, "cinnamon" refers to Ceylon cinnamon.

Personal report

UPDRS:

Date started cinnamon treatment: November 6, 2020. UPDRS score at start of treatment: 35

My score had been 25 prior to a misadventure with another treatment. Cinnamon treatment improved my status as compared to before that event: UPDRS score as of completion of treatment on December 29, 2020: 20. (For those unfamiliar with UPDRS, lower is better)

My main symptom is motor impairment which has been much improved. I do have some tremor which is unchanged.

Medication Reduced:

I am very sensitive to levodopa - too much interferes with my walking, causing my leg on the affected side to be too tight and unable to move easily. Levodopa dosage prior to starting cinnamon treatment: 100 milligrams 3x daily, as Carbidopa / levodopa 25/100 ER. Exercise with medication in "ON" state. Levodopa dosage at December 29: 50-100 milligrams 2x daily, as Carbidopa / levodopa 25/100 ER. I now exercise in the "OFF"/unmedicated state because any additional levodopa is too much.

Motor improvements:

Dexterity has been restored to my affected arm - I am now able to manipulate buttons equally well with my affected hand. I walk more easily – A person who had not seen me for several weeks remarked I was no longer dragging my leg. These abilities are an improvement over my status prior to the misadventure I mentioned above, as is the need to exercise in the off state.

Personal observations indicating underlying disease condition is improved:

In past attempts at herbal remedies, motor improvement came at a cost - dystonia, which was unacceptable, and indicated some adverse change was occurring as well as favorable change. That has not been the case with cinnamon. Improvement was gradual since the start of this treatment, and improvement has been maintained in the month since end of treatment. This is unlike a symptom reducing medication that merely increases the overall amount of dopamine present.

Adverse effect:

During most of the seven week treatment period I took approximately 3 g of cinnamon daily, mixed with food over the course of the day, without adverse effect. During the final week I increased my dosage to 6 g daily which triggered an inflammatory condition that had been in remission. Since then I have been working to get that inflammation back under control. Attempts to resume cinnamon treatment at lower levels have been met with re-triggering the inflammation.

The literature supports the idea that although cinnamon is anti-inflammatory in the brain, it is pro-inflammatory elsewhere in the body.

Evidence From The Medical Literature

Effect on inflammation:

According to animal data at academic.oup.com/jn/article..., cinnamon is pro-inflammatory in macrophages, an immune cell that exists outside of the brain. Table 3 in this study lists macrophage messenger RNA levels, as a multiple of baseline, as a result of exposure to:

"CPE" - cinnamon polyphenol extract. "LPS" - lipopolysaccharide, a component of bacterial cell walls and one of the most inflammatory compounds in existence.

.......................CPE............ LPS

TNF ..............6.2 ..............48

COX2 ..........3.4 ..............532

IL-6............... 3.2 ...........1865

Although the cinnamon extract was not as inflammatory as LPS, it did promote inflammation.

On the other hand, according to this study, link.springer.com/article/1... cinnamon essential oil had an anti-inflammatory effect on the microglia, which are immune system cells inside the brain: "Our results showed that TCA [cinnamon essential oil] significantly ... decreased iNOS and COX-2 protein expression level ...It also reduced LPS-induced mRNA expression of iNOS, COX-2, and TNFα."

Safety profile:

In a study of diabetics here: pubmed.ncbi.nlm.nih.gov/146... 10 patients each took 3 or 6 g of cinnamon daily for 40 days without any adverse effects reported. In another study, here: link.springer.com/article/1... 30 subjects participated in a three-month escalating dose study. At the final month they took a daily capsule of cinnamon extract equivalent to 6 g of cinnamon - which is to say concentrated cinnamon. Four suffered digestive upset, and two dropped out of the study for that reason. No other adverse effects were reported. We are not taking cinnamon extract, and mixing cinnamon with food or drink minimizes the likelihood of digestive upset.

Animal studies found excellent safety, which was reviewed here: pubmed.ncbi.nlm.nih.gov/226...

Therapeutic effect:

Researcher Kalipada Pahan has spent many years studying the effect of cinnamon on Parkinson's and published numerous studies, most recently here: link.springer.com/article/1...

"The present investigation underlines the importance of a naturally used spice and flavoring agent viz. cinnamon in reducing α-syn deposits in transgenic mice expressing mutant A53T human α-syn. Upon oral administration, cinnamon markedly reduced the level of insoluble α-syn in nigra, hippocampus and brain stem of A53T mice... Glial activation plays an important role in the pathogenesis of various neurodegenerative disorders including PD... and we found suppression of microglial and astroglial activation in the nigra of A53T mice upon cinnamon treatment. Moreover, neuroprotective proteins like DJ-1 and Parkin are known to reduce the formation of Lewy bodies in the CNS. Accordingly, we observed upregulation and/or normalization of DJ-1 and Parkin in the nigra of A53T mice by treatment with cinnamon...

"Quantification of α-syn immunostaining indicated a significant reduction of α-syn in cinnamon-treated mice relative to the vehicle-treated group...cinnamon treatment decreased the level of insoluble, but not soluble, α-syn in the nigra ofA53T mice... Mice were treated with cinnamon (100 mg/kg body wt/d) ... via gavage for 60d. "

Adjusting for metabolic rate as set forth here: ncbi.nlm.nih.gov/pmc/articl... the mouse dosage is equivalent to 8 mg/kg body wt/d for a human, about .5 g for a 60 kg (132 pound) human. This may or may not be an effective human dosage.

Disclaimer:

I am not an M.D., just a fellow member of the Parkinson's club. I cannot offer any guarantees, nor assume liability. If you try the cinnamon treatment and some adverse effect arises you should stop.

Contraindication:

Anyone with a serious allergic or autoimmune condition such as lupus, multiple sclerosis, allergic arthritis, serious allergies, etc. should look elsewhere for treatment.

Update - In addition, you should take a break from cinnamon treatment if you suspect you have Covid-19 or if you receive a Covid vaccination, and stay off of cinnamon until all signs of inflammation have subsided.

Suggested Cinnamon Dosage Range:

.5 – 3 g of cinnamon daily, added to food or drink. One gram of cinnamon is approximately one half level teaspoon. I strongly recommend getting a sensitive scale for accurate dosing. If you decide to go with the higher-end dosage, I suggest it be divided into two or three portions over the course of the day. Add cinnamon after food has been cooked so as not to subject it to extended elevated temperatures.

Keeping track:

You can self administer the UPDRS (Unified Parkinson’s Disease Rating Scale) to track your progress. This will not be as objective as having an observer administer the test, but for tracking any changes it will suffice. If you choose to do this, I suggest omitting the back pull test, even if you do have a partner available for this, because there is the danger of falling and injury. The UPDRS can be accessed here:

movementdisorders.org/MDS-F...

I hope this helps!

-------------------

Update – People are asking about what brand of cinnamon to use. I have no particular insight as to any brand being better than another. Here are couple brands I have used that seemed to be satisfactory:

amazon.com/gp/product/B0041...

amazon.com/gp/product/B07K7...

139 Replies

Wow this is great information. Thank you!

Thanks so much for this PB, greatly appreciated!

Thank you for this park-bear! There is another forum member from Italy using cinnamon, but I don't think he has reported any updates other than to say he has been using it for quite sometime. I can't remember his name as he does not post often, but it has been years. I wish he would update on his experience too!

On a related note, Ceylon cinnamon is superior tasting to the common cinnamon cassia and the other two common ones. A much smoother taste imo. I take Ceylon cinnamon in capsules @ 600 mg each, which may be useful for those who are not wild about the taste of cinnamon. Wait, is that even possible??? 😜😜😜

amazon.com/NutriFlair-Cinna...

Art

Hi park_bear:

You said "My main symptom is motor impairment which has been much improved. I do have some tremor which is unchanged."

"motor impairment" is such a broad term. Can you give specific examples of things that improved (e.g., the specific sections of the UPDRS exam where your score improved)?

Thanks!

park_bear profile image
park_bear in reply to Levod

I prefer to keep my answer simple - improved dexterity of my affected arm and improved ability to walk with my affected leg. I still have some some impairment of the leg, but my motor ability of the affected arm seems close to normal.

Levod profile image
Levod in reply to park_bear

Simple is good, but I wanted to get a better understanding of what your "Parkinson's experience" is like. For me it is mostly about bradykinesia (slow movement) and tremor on my right side.

park_bear profile image
park_bear in reply to Levod

My tremor is not changed. I have not had major bradykinesia, but I do have the impression I am a bit quicker than before.

Nice research P_B. I just ordered 1lb of ground Ceylon Cinnamon, Nature Vibe brand. Will give it a try. I've always loved Cinnamon - JG

Seems to be potentially useful, worth looking into.

Finally there is a yummy remedy for PD :) Thank you PB!

It has been known that cinnamon helps to eradicate H. Pylori and some studies indicate the connection between H. Pylori and PD, stating that eradication of H. Pylori improves motor skills in PwP.

clinical.r-biopharm.com/new...

Makes you wonder if all PwPs should be screened for H. Pylori?

park_bear profile image
park_bear in reply to faridaro

Interesting!

My consultant did actually recommend being screened for H. Pylori. I'm waiting for my result...

NRyan profile image
NRyan in reply to Smokeypurple

What is the screening for H Pylori? Do they do an endoscopy?

Smokeypurple profile image
Smokeypurple in reply to NRyan

It was a faecal sample...

Despe profile image
Despe in reply to NRyan

I had an endoscopy for GERD. H. Pylori was negative.

ConnieD profile image
ConnieD in reply to NRyan

For my test the lab had me breathe into some kind of bag. Thankfully it was negative

laglag profile image
laglag in reply to Smokeypurple

Keep us informed.

Smokeypurple profile image
Smokeypurple in reply to laglag

Just called the surgery to check if results in and stool sample came back negative for H. Pylori. Interesting that neurologist mentioned it though.

Thank you so much Park Bear! I will be adding more Ceylon Cinnamon with greater confidence now. Since you research in such depth, I'm wondering, do you use resveratrol, lion's mane mushrooms or ashwagandha powder? In his book Healthy Brain Toolbox, Dr. Ken Sharlin recommends all those I just mentioned. I have been eating via actual mushrooms and via mushroom powder the lion's mane. I am also interested in Cascara (Coffee cherry) because of its high antioxidant properties. Have you heard of it?

park_bear profile image
park_bear in reply to cclemonade

Thanks for the kind words. Sorry not using any of the ones you mentioned.

AaronS profile image
AaronS in reply to cclemonade

Reservatrol is good but look up pterastilbene I think its called, I may need correction there

cclemonade profile image
cclemonade in reply to AaronS

Thank you Aaron. I will. I just zoomed in on your photo for the first time. You have a little strawberry blonde! I was a strawberry at that age. These two might be common on HU but L-taurine and Citicoline are good.

I’m determined to keep myself taped together for my kids.

cclemonade profile image
cclemonade in reply to AaronS

Pterastilbene does look to be better! Thank you!

Millbrook profile image
Millbrook in reply to cclemonade

Getz posted on coffee cherry increasing BDNF by 141%. My husband is now on his 3rd bottle of coffee cherry by swansons.

So 3 to 6 g is 1 teaspoon to a tablespoon?

park_bear profile image
park_bear in reply to MissRita

One the level teaspoon would be about 2 g. The level tablespoon would be about 6 g. Best to measure with a scale.

MissRita profile image
MissRita in reply to park_bear

Thx!

rescuema profile image
rescuema in reply to MissRita

I just measured my 1 level tsp and it was 3g, so probably varies per product and moisture content.

park_bear profile image
park_bear in reply to rescuema

Thanks for documenting the variability. Why it is important to use a scale!

laglag profile image
laglag in reply to park_bear

I'm anxious to try the Ceylon Cinnamon. I sent this to you because I respect your opinion. So, no hurry on sending your opinion. Do you believe the powder to be better than capsules? I've attached a few products from Amazon. Do you have any pros and/or cons on either one? Is it better to stay away from the other added antioxidants in the first capsule? The first link I sent sounds like a "super-pill"?

amazon.com/Cinnamon-Berberi...

amazon.com/Organic-Cinnamon...

amazon.com/dp/B071HSW2MY/re...

Thank you,

laglag

park_bear profile image
park_bear in reply to laglag

I personally prefer the powder because it can be mixed with food instead of adding yet another capsule to the ones that I already take. Plus less chance of digestive upset.

Regarding the first link, there are half a dozen other ingredients in addition to cinnamon. If you try it you are doing a different experiment than just taking the cinnamon.

I've been using about 2 grams of Ceylon cinnamon a day for a few y ears now. I'm not as scientific as Park Bear in monitoring and reporting results, but I can tell you that my symptoms have pretty much stabilized. This is something that is simple to do without putting another drug into your system. Why not try it?

laglag profile image
laglag in reply to SonarsMom

What brand do you use?

SonarsMom profile image
SonarsMom in reply to laglag

I've bought different brands through Amazon. I only buy organic and depend on the reviews before I purchase.

MissRita profile image
MissRita in reply to laglag

I just bought a bag from Frontier.

ladyaudree profile image
ladyaudree in reply to SonarsMom

May I ask what you weigh? Thinking about the dosage if I try it. I am a small woman 115 lbs.Thanks

SonarsMom profile image
SonarsMom in reply to ladyaudree

I weigh 160.

Thanks PB! This was on my list of things to do since I read that Palan article a month or so ago - now actioned!

Thanks for pointing out cinnamon to me. I have been taking the 3g/day. It took about 5 min to decide to do it as I love cinnamon. And how is it working? I have been feeling good. (I take a lot of other stuff as well so I can't say for sure...this is a therapy I can enjoy and it will crack me up if it ends up the the cure for PD is something so available, inexpensive and well loved.

MissRita profile image
MissRita in reply to pmmargo

Hope! 🙏🏼

MissRita profile image
MissRita in reply to pmmargo

How do you take it?

pmmargo profile image
pmmargo in reply to MissRita

Dear Rita,

Orally? I should keep an open mind though. It is in a pill from HerbTonics 1500mg per pill. Amazon.

Hugs, Paul

PS You can still taste it a bit even though the cellulose.

MissRita profile image
MissRita in reply to pmmargo

I assumed oral but I just meant do you just do teaspoons in water or do you do capsules etc.

pmmargo profile image
pmmargo in reply to MissRita

Sorry just being silly me.

MissRita profile image
MissRita in reply to pmmargo

Lol It’s all good

Not to be taken like this!

Sorry I couldn’t resist and it made me laugh!

m.youtube.com/watch?v=87Cwa...

rescuema profile image
rescuema in reply to Buckholt

🤣🤣🤣🤣🤣😂😂 Gave me some wrinkles. Hillarious!

MissRita profile image
MissRita in reply to Buckholt

Lmaoooooo

Park Bear I’m commenting again bc I can’t help myself. I am grateful for your research and your scientific approach. And it encourages others like myself to pursue doing the same.

I have cinnamon essential oil. Worth trying?

park_bear profile image
park_bear in reply to jombi

Cinnamon is cheap and no need to add another variable.

Thanks for the pioneering effort on Ceylon Cinnamon for PD. Will of course be on this trail. 🌺🙏🏾🌺

But it has been such an embarrassment of riches these last few months that I am going to be late to the party.

(1) There is my personal Niacin/Butyrate project for *gut barrier strengthening and inflammation reduction*. Started Niacin mid October 2020 with good results on symptom relief for Bradykinesia by early January 2021. The Butyrate is in the cupboard. Intake starts this weekend.

(2) There is the High Dose Melatonin project, being pursued: defensive measure against *REM sleep behavior disorder*. On going but have not arrived at the therapeutic range yet: 1mg per kg. This suggested by chartist

(3) The Nrf2 project: broccoli seed, broccoli sprout, moringa, all potent food sources for *Nrf2 activation*. This suggested by wriga. I am using moringa powder to make a cold tea. Project just off the ground.

(4) I have Blue Spirulina Powder - Phycocoyanin, in the cupboard. Mark F. McCarty, a health researcher suggest that superoxide production by the enzyme NADPH oxidase can be down-regulated with spirulina or phycocyanobilin-enriched spirulina extracts. Superoxide reacts with Nitric oxide to produce the deadly *Peroxynitrite* radical. Start date in a month or two.

(5) And now this - Ceylon Cinnamon for PD *motor impairment*. Needless to say I have surveyed Amazon and put the desired product on my shopping list. Will order shortly. And once it arrives I will replace the Cassia Cinnamon I use with Ceylon Cinnamon and continue use of cinnamon in the same manner as I currently do, until I spring for the therapeutic dose.

Keep it coming guys: the future so bright, I got to wear shades

✨😎✨

Melatonin scavenges peroxynitrite, which is at elevated levels in PwP.

Art

So good to know 🌺 Seem to have missed this ✨🙏🏾✨

Thanks Casey!

Particularly interested in your butyrate and moringa results. Please keep us posted.

Will do my friend. Will do📌

cclemonade profile image
cclemonade in reply to park_bear

Park Bear, do you know of any reason why I shouldn’t mix the cinnamon with turmeric? Do you think that’s okay? This morning I had the strongest coffee of my life with 1 tsp of cinnamon, 1 tsp of turmeric, 1 tsp cacao and black pepper. Do you think combining with these other nutrients is okay?

park_bear profile image
park_bear in reply to cclemonade

No conflict as far as I know. Add cinnamon just before consumption to minimize heating.

laglag profile image
laglag in reply to cclemonade

While searching for Ceylon Cinnamon (CC), I came across this supplement & thought it might be helpful. I just ordered CC & will try it first.

Too bad Simon Stott doesn't read this forum. Send him your summary Casey.

Thanks for the compliment MBA 🤓.

Some of us know so much that it paralyzes: they already know what ever you propose can’t work.

Some know so little that they do not have a basis for action: in a sense they too are paralyzed.

I like my position on the knowledge tree: I know just enough to be dangerous ✨😀✨

Be sure the spirulina is from a pure good source to be free of BMAA and heavy metals.

Indeed!

Spirulina is a cyanobacteria: emphasis here on ‘bacteria’ 🔬

The contamination is a big problem, the reason why I stopped taking spirulina.

Sydney75 profile image
Sydney75 in reply to rescuema

There is a brand pure Hawaiian Spirulina that is grown in a fresh Hawaiian aquifer with out using pesticides and herbicides. An alternative is fermented chlorella that is grown in a sterilized bio-reactor (lab) brand is Dr. Mercola.

rescuema profile image
rescuema in reply to Sydney75

The Nutrex Hawaiian Spirulina is the last brand I used and it's probably what I'd suggest of the ones available as well, though they do use a portion of ocean water outside their control and cannot be certified organic. My personal choice is not to gamble on the many unknowns anymore (despite manufacturers' claims) given the myriad growing global pollutants, and I've even given up on indulging mussels and clams, and lately even sardines due to microplastics. Very sad.

drweil.com/diet-nutrition/f...

It's good to watch documentary "The Toxic Puzzle" (if you hadn't watched it yet) before starting spirulina.

Thanks my friend. I have not seen the film but I am acquainted with the premise on which it builds.

Will take a look- hope they are good storytellers. 🌺

How do you take your cinnamon?

As a flavoring on my oats - such a bland food, highly rated by my daughter, a former champion bodybuilder.

When we bake muffins - a banana/wheat/coconut milk combo - we use as much as a tablespoon per pan.

In both instances the cinnamon is subject to high heat. Will need to make some adjustments for therapeutic use 🌺

For the oatmeal, easy enough to stir in the cinnamon just before consumption

Hi, just curious to see how/if any of these have worked out ! fingers crossed...

Still way off, of a therapeutic dose. Still flavoring - one tea spoon - when porridge cools.

I suspect that it would be hard going at therapeutic levels, because it gets gritty with the product I have.

Do have a relatively expensive brand I bought from Amazon, that I have to try.

Tablets are so much easier to take 🙈

Not sure which substance you referring to, but if it is cinnamon, one teaspoon, which is about two grams, is in the ballpark of a therapeutic dose. The versions of cinnamon I have tried have been fine powders and not gritty.

Ok then - will stop my local version - Ceylon Cinnamon from Grenada, the spice isle of the Caribbean.

I have a 4oz pack ‘Burma Spice’, off Amazon. Will see how it goes 🌺

I got Frontier cinnamon from Amazon. No complaints and at $12 a pound a very reasonable price:

amazon.com/gp/product/B0041...

Amazing.

If someone, other than you, were to tell me that the every day, dime-a-dozen, run-of-the-mill spice cinnamon would provide me relief in my Parkinson's, I would say, "Spare me, please. Tell it to Ozzie Osborne."

park_bear profile image
park_bear in reply to MBAnderson

:-)

It is an excellent post! Thank you!

"Add cinnamon after food has been cooked so as not to subject it to extended elevated temperatures."

Is a compound in cinnamon heat-sensitive? Do you have a source for this information?

I've been using Ceylon cinnamon for many years but always in hot teas, cooking or baking.

park_bear profile image
park_bear in reply to rescuema

pubs.acs.org/doi/pdf/10.102...

" trans-Cinnamaldehyde, the principal component of cinnamon flavor, is a potent antimicrobial compound present in essential oils such as cinnamon.... starting at ∼60 °C, pure cinnamaldehyde undergoes a temperature-dependent transformation to benzaldehyde under the influence of heat"

rescuema profile image
rescuema in reply to park_bear

Thanks! I just drank 1tsp (3g) in cold water even before seeing your response - yummy but pretty concentrated and my stomach is definitely feeling it afterwards. I think I"ll reduce the dosage to 1/2 tsp or less and see how it goes.

park_bear profile image
park_bear in reply to rescuema

When I consume it in drink I add 1 g to a small cup of almond milk. I do warm it a bit also, but not hotter than I can can comfortably drink.

rescuema profile image
rescuema in reply to park_bear

Probably a good idea to mix with some food. I'm getting a bit of headache now and feeling a bit off - lol, price of self-experiment. It's probably better for my kidneys to consume with some roughage. Almond milk is out for me - I'm sensitive to oxalates.

park_bear profile image
park_bear in reply to rescuema

I am able to consume 3 g without digestive upset by adding it to a large bowl of oatmeal just before eating.

rescuema profile image
rescuema in reply to park_bear

Yes, experiencing digestive upset! haha. I've always added Ceylon to my oatmeal at the end of cooking. I'll let it cool a bit further before adding it from now on.

Rhyothemis profile image
Rhyothemis in reply to park_bear

The active metabolite is benzoate; benzaldehyde converts to benzoate.

pubmed.ncbi.nlm.nih.gov/168...

"Benzaldehyde is absorbed through

skin and by the lungs, distributes to all well-perfused organs, but does

not accumulate in any specific tissue type. After being metabolized to benzoic acid, conjugates are formed with glycine or glucuronic acid, and excreted in the urine."

Have been giving my mother Ceylon Cinnamon daily, since many years (almost 5 now).

That is so helpful! I’ve been using Ceylon cinnamon for quite a while now, but I don’t think I’m taking enough. So I’m gonna bump it up and see what happens. Thank you so much for all this information! It’s neat to see folks excited about cinnamon and the potential. I’ll start with a higher dosage tomorrow. Thank you!

Hidden profile image
Hidden

Cinnamon: Potential Role in the Prevention of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes

ncbi.nlm.nih.gov/pmc/articl...

I think PD is linked to insulin resistance. Cinnamon helps in this aspect.

park_bear profile image
park_bear in reply to Hidden

Yes, cinnamon is helpful in prevention and treatment of type II diabetes:

pubmed.ncbi.nlm.nih.gov/146...

"RESEARCH DESIGN AND METHODS— A total of 60 people with type 2 diabetes, 30 men and 30 women aged 52.2 +/- 6.32 years, were divided randomly into six groups. Groups 1,2, and 3 consumed 1, 3, or 6 g of cinnamon daily, respectively, and groups 4, 5, and 6 were given placebo capsules corresponding to the number of capsules consumed for the three levels of cinnamon. The cinnamon was consumed for 40 days followed by a 20-day washout period.

"RESULTS— After 40 days, all three levels of cinnamon reduced the mean fasting serum glucose (18–29%), triglyceride (23–30%), LDL cholesterol (7–27%), and total cholesterol (12–26%) levels; no significant changes were noted in the placebo groups. Changes in HDL cholesterol were not significant"

Although Ceylon cinnamon is slightly lower in oxalates than regular Cassia cinnamon, it still has a high amount of about 31mg in a tsp. Being deficient in certain nutrients such as B1, B6 (P5P), molybdenum will also affect endogenous oxalate synthesis and metabolism. Anyone sensitive to oxalates should be cautious of its adverse effects and possibly complement with calcium citrate or other calcium-rich food to bind the oxalates when increasing cinnamon consumption regularly.

Signs of high oxalates-

"Symptoms of high oxalates include pain, burning, fatigue, muscle aches, foggy brain, frequent urination and kidney stones. The thyroid will also suffer as oxalates can bind to T3 and disturb thyroid function. Oxalates will also reduce glutathione levels and increase oxidative stress, induce histamine release and interfere with sulfate metabolism."

anthrobotanica.com/low-oxal....

sallyknorton.com/which-spic...

park_bear profile image
park_bear in reply to rescuema

webmd.com/diet/foods-high-i...

" Most people get between 200 and 300 milligrams of oxalates daily. If you’re at risk for kidney stones, sources suggest consuming less than 100 milligrams a day. Doctors may also recommend “low-oxalate diets” of less than 50 milligrams daily for some people...

High oxalate foods include:

1. Spinach

Leafy greens like spinach contain many vitamins and minerals, but they’re also high in oxalates. A half-cup of cooked spinach contains 755 milligrams.

2. Soy Products

Products made from soybeans are excellent sources of protein and other nutrients, especially for people on a plant-based diet. However, they are also high in oxalates. A three-ounce serving of firm tofu has 235 milligrams, while 1 cup of soy milk or yogurt can have up to 336 milligrams per serving. "

rescuema profile image
rescuema in reply to park_bear

Spinach (especially) and potatoes are indeed the big ones. Some people sensitive to oxalates will feel even a small amount depending on their status if they happen to also produce it endogenously under oxidative stress. Hyperoxaluria is an increasing phenomenon nowadays, especially with gut dysbiosis and candida.

Thank you, Ceylon cinnamon also lowers blood sugar if you run a little high.

PB,

Excellent post with valuable information. I didn't know that cinnamon is heat sensitive. I have been using it in anything edible as I love cinnamon and I have used it heavily all my life. :)

I have been purchasing pure Ceylon cinnamon oil (not essential), and my husband was adding a couple of drops in his breakfast. The cinnamon smell was too intense so he started the powder 3-4 days ago.

Before I boil water for my tea, I add to the water orange peels and a couple of Ceylon cinnamon sticks. Guess I have to stop adding the sticks.

Thank you so much for more info to help with PD. I think, for now, I will save this information to add to my husbands regime after we give the HDT a try & get dosage regulated & see if that works. His anxiety is the most troublesome for him.

Last night we had to go to a family get together & he was feeling anxious. So we took a few minutes before we left & I massaged his tremor foot, we did some deep breathing & I rubbed some homemade magnesium oil on his back (he has chronic back pain) and on his tremor foot. He felt good all evening till just before we left. So I guess this will be our new habit before we go anywhere while we wait for his HCL to arrive.

I just don’t want to start too many things at once even though it’s tempting to run out & get him started on the Ceylon right now.

I take it that the Ceylon doesn’t help with anxiety?

Again thank you for your research & sharing your information & results.

park_bear profile image
park_bear in reply to Lizzy9

I agree with only undertaking one intervention at a time.

Anxiety is not one of my main symptoms so I cannot report the impact of cinnamon.

Back pain can be a Parkinson's symptom and I find it does respond to levodopa.

Thanks for kind words!

delboy381 profile image
delboy381 in reply to park_bear

After how many days can the result be noticed or not?

park_bear profile image
park_bear in reply to delboy381

For back pain responding to levodopa – a couple of hours

delboy381 profile image
delboy381 in reply to park_bear

Sorry, I meant the general effect of cinnamon?

park_bear profile image
park_bear in reply to delboy381

A month or two

delboy381 profile image
delboy381 in reply to park_bear

Thanks.

delboy381 profile image
delboy381 in reply to Lizzy9

I had a similar problem, my advice for anxiety is to let her go don't give her your attention just let her go with affirmation in yourself release it she will start to fade. Also warm cold shower 1 minute warm 30 seconds cold try it.

7 Ways to Identify Ceylon Cinnamon from Cassia Cinnamon (Buying Tips)

benefits-of-honey.com/ceylo...

park_bear profile image
park_bear in reply to Farooqji

At Amazon the Ceylon cinnamon is clearly designated as such. The Cassia cinnamon has various designations including "Saigon" cinnamon. Contrary to the text at the link the pricing of the two is similar. Also, I personally find the aroma of both varieties of cinnamon to be pleasing.

amazon.com/s?k=cinnamon

park_bear,

It has been about a month now since you posted this and I was wondering if you have any further updates on your symptom improvements from Ceylon Cinnamon?

Art

park_bear profile image
park_bear in reply to chartist

Even though I have not been able to resume the cinnamon because of the inflammation problem the restoration of dexterity in my affected arm and hand has been maintained. I can manipulate buttons unimpaired with either hand, which had not been the case prior to treatment.

chartist profile image
chartist in reply to park_bear

It is good to know that the results are durable!

Art

Thanks PB think i 'll add some to my porridge. Two great food stufffs cinnamon and porridge. Lovely

I am using Ceylon cinnamon as a tea , my medicine working better when i take Ceylon cinnamon tea .I take 2 cups of cinnamon tea one cup in the morning and one in the evening .

I am taking 4 tablets stalevo 150 mg 4 times a day .

Thank you park_bear for this post .

PARK,this seems to good to be true snd so why wont they deliver it to me in the USVI?

park_bear profile image
park_bear in reply to JBOVERT

I have no idea. It is readily available in mainland US.

Park so you have been taking cinnamon and you decided to stop.... why? I just placed my order and soon I wil have a pound of it...

park_bear profile image
park_bear in reply to JBOVERT

As I said it aggravated a pre-existing inflammatory condition.

How long did it take for the effects to become noticeable? HOW LONG WERE YOU TAKING IT?

park_bear profile image
park_bear in reply to JBOVERT

I stated that clearly at the beginning of my personal report

PARK, My cinnamon arrived yesterday and i started off taking about 1/2 tspn on some toast with some sugar and butter to start off with then this morning i got up and had the same thing so now it is occurring to me that there must be other recipes for taking your dailey dose of ceylon? Any of these come to mind? Cause i love cinnamon toast but i need some other options:) also i was thinking that i have a lb of thiamine powder coming to theisland that now i ws thiinking of getting a hold of my doctor and asking him if he can give me a shot of b-1 What are your thoughts regarding the dosage for a start off shot?

park_bear profile image
park_bear in reply to JBOVERT

For thiamine injection dosages see here:

highdosethiamine.org/

I found the mixing cinnamon in oatmeal after it has been cooked works well. I also like to add sunflower seeds and berries or chopped fruit. I find this these additions make otherwise boring oatmeal quite enjoyable.

It also works for me to mix cinnamon with almond milk. Any other milk would do, or yogurt.

I do suggest undertaking interventions one at a time to see how each is working before adding another.

laglag profile image
laglag in reply to park_bear

Try some peanut butter in your oatmeal along with the cinnamon. 😋

JBOVERT profile image
JBOVERT in reply to park_bear

HI Park, hey thanks for the cinnamon help I'm pretty much the king of oatmeal now thatI have an abundance of it around ...I have a plan to have it on some salmon but am not sure how I will introduce it to the fish... not so sure the heat won't affect it adversely so I am going to just sprinkle some on to try it like that first...just ordered a small scale but until it gets here Im wondering how many grams is a heaping teaspoon? any idea? Im figuring it must be close to 4 grams...any thoughts?

park_bear profile image
park_bear in reply to JBOVERT

Yes, approximately

Does it have to be from Sri Lanka? My spice store sells Cinnamomum verum from Mexico. I assume it’s all the same as long as it’s “true” cinnamon.

park_bear profile image
park_bear in reply to FawnLily

Correct. As long as it is the right species the location grown does not matter.

GOOD MORNING PARK..I HAVE BEEN TAKING APPROXIMATELY 5-6 GRAMS EVERY MORNING:

I have tried to take my cinnamon at the same time very day

I have tried to measure it out on a gram scale but it is way to messy so I just get a heaping teaspoon full and throw it in the bullet with about a 1/2 teaspoon of ashwagonda powder a small banana and about a 1/2 teaspoon of cane sugar and that is all mixed with a lactose free fat free milk

There is not much change in my condition yet but I'm continuing without abandoning any thing....

park_bear profile image
park_bear in reply to JBOVERT

As long as there are no adverse effects stick with it for a couple months. Also you should self administer the UPDRS and note your medication requirements to measure any changes.

PARK I am not on any medication for "this" disease....I plan on doing this regimen for at leas 3 months to see where I am after around 30 days then 60 then 90. I have a problem with swallowing and drooling and my left side is definitely lagging behind the right side ...so I am not sure whether this protocol is going to be the thing for me....I am thinking that if the retrotope people will share their doctors names with me that I will be able tp access the RT001 poly unsaturated fatty acid= PUFA TREATED WITH DEUTERIUM IS what makes this pill able to penetrate the blood BRAIN barrier...so far its been like less than reasonable not sure what to do at the point....Jim

Would using ceylon cinnamon in general be a good choice rather than taking a high amount? Also curcumin and resveratrol are good for inflammation. Your thoughts. Thanks

It surely will not hurt, but it is unlikely you will get enough to have a therapeutic effect.

Just a little nervous about overdosing and creating more problems. I'm scheduled for an MRI this week to determine either groin injury, hip flexor injuries or hip injury in addition to that I. Can't sit for long without my leg and foot going numb .Possibly sciatic nerve or arthritis. Any advice would be appreciated

The one thing we are least well-equipped to do here is diagnosis. Hopefully the doctors will figure out what is going on. My guess would be pinched nerve but that is merely a guess.

Regarding the cinnamon, start with whatever level is comfortable for you, and only increase to the extent that you are comfortable with.

Thank you

On a recent blood test I asked to have my folate checked. It came back 28. My primary care dr said to cut back my vitamins but didn't specify which ones.my nutritionist/pharmacis said to stop all b12 for 6 weeks and get b12 tested along with folate. Your thoughts. I have not eliminated my organic multivitamin, mineral amino acid. There is some b12 in that

There are different units used for blood plasma folate measurement. Depending on the units used for the measurement, yours could be way high or middling. In general folate supplementation in the Western diet is unnecessary and is carcinogenic. See my writing here for details:

Folate Supplementation Carcinogenic

tinyurl.com/ycdrz5lj

I use B- from Seeking Health which omits both folate and B12. I supplement the B12 separately. I would not agree with skipping a B12 supplement.

How do you lower the folate level?

If you stop supplementing it should take care of itself.

laglag profile image
laglag in reply to park_bear

What happens if you take too much cinnamon?

park_bear profile image
park_bear in reply to laglag

As set forth in my post above, 6 grams per day was well-tolerated in a human trial. I looked and was unable to find any reports of human toxicity due to Ceylon cinnamon. As I reported I experienced an increase in existing inflammation at six grams per day dosage.

Animal safety data:

onlinelibrary.wiley.com/doi...

"Anand et al. (31) studied the effect of 5 (100 mg⁄ kg), 10 (200mg⁄ kg) and 20 (400 mg⁄ kg) times the effective dose (20 mg ⁄ kg) of cinnamon on healthy Wistar rats. They observed no behavioural changes (excitement, nervousness, dullness, alertness, ataxia or death). ... The insignificant increase in aspartate aminotransferase, alanine aminotransferase and alkaline phosphates values observed in animals administered with 20 times the effective dose after 72 h returned to their initial values within 120 h of cinnamon administration. The administered doses are comparable to a human adult dose of 600–2400 mg⁄ kg ...The 50% median lethal dose value (LD50) of orally administered cinnamon was 1850 mg⁄ kg [39]. Hence, based on the above formula, the LD50 for an adult human would be 11.4 g ⁄ kg."

So for a 50 kilogram human LD50 would be over a pound of cinnamon.

Fantastic work. And very much appreciated