My mom is on high dose B1 and we are actually starting to see improvements.
She also takes D3, Coq10, magnesiums, vitamin c, collagen, b12, melatonin, probiotic and d manose.
Is there anything that should be added or that she takes that isn’t necessary?
What are your top supplements for PD?
The supplement that gives the most improvement for an individual may hint at what caused PD for that individual. It's also difficult to tell the difference between improvement and feeling better, but people with PD do need to feel better.
Try Hardy’s daily essential nutrients which can replace the individual vitamins and minerals plus it has a range of other compounds in it which are useful.
If she has a digestion problem, rosacea, acne, or feels sick and nauseous a lot try alternating Berberine and allimed (strong garlic extract) weekly with the probiotic. Plus a digestive enzyme.
For motivation try horny goat weed.
See my profile for other supplements my husband is using. I’m not entirely sure which other things have helped him but he is feeling much better than he has for years.
Parkinson's seems to be such an individual disease that anything which works for one of us may not work for others. That said, I believe the supplements which help me the most are high doses of B1 (Thiamine), B3 (TruNiagen), and B12. The benefits of B1 and B3 are pretty well documented on this site. Here's an article about B12:
NAC, CQ10, citicoline, turmeric, B1, Vitamin D3, magnesium, celery seed extract all have research indicating improvement in PD symptoms and I learned about all of them on this site. My MDS is aware of everything I take and has mentioned that NAC has research substantiating it’s efficacy.
It sounds like you are on the right track. All diseases are caused by toxins, lack of nutrition, and stress. You might research a good probiotic and a good prebiotic. My husband is loaded with chemicals from agent orange in VietNam. He is doing saunas, and also has done chelation to get rid of the high lead.
Does anyone know if you can take NAC if you are allergic to sulfa drugs? How much B12 is suggested?
I am curious about what she is using D-Mannose for? I usually only suggest it for urinary tract infections (UTI) .
The type of magnesium can be important as some forms are more absorbable and some forms are helpful with dealing with constipation while the topical magnesium chloride oil or mag oil (MO) is very useful in the spray form for quick relief from muscle cramps, stiff or tight muscles and achy joints from PD or arthritis.
Vitamin D is a good choice overall and PWP are known to generally have lower levels than non-PWP. Vitamin D is also neuroprotective.
Melatonin is one of my favorite supplements. It is neuroprotective, a highly potent antioxidant that can recycle/reduce other antioxidants and increase levels of catalase, glutathione and SOD.
B-1 is good for PD.
Probiotics are multi-faceted and good for AD and PD.
B-12 in the right form can provide an energy boost if well enough absorbed and has shown itself to be useful in PD.
Vitamin C and collagen are useful together.
Co-Q 10 is useful for mitochondria if enough is taken.
Overall, a very nice list of supplements! I imagine a high quality omega 3 supplement would offer some important antiinflammatory qualities.
I wrote a post about supplements that show potential to inhibit interleukin-8 and may be useful in PD :
healthunlocked.com/parkinso...
Art
Thank you for your reply.
I’m thinking of adding NAC and B6 or a B complex.
She takes the D-Mannose (one each morning) to prevent a uti since she wears a diaper at night and usually wets the bed. She was getting them quite often but so far since taking it, she hasn’t had one.
And yes, I want to add a good omega 3 and turmeric. She has terrible arthritis in her hands.
She takes magnesium threonate and magnesium glycinate. She also use theraworx on her calves and feet.
D-mannose is mainly effective against UTI's that are caused by Ecoli bacteria because it binds the bacteria and prevents it from sticking to the urinary tract surfaces and allows the bound bacteria to be flushed away. Baking soda is effective for some bacteria and sea salt can be also.
The B-complex sounds like a good choice. B-6 at too high of a dose can be a problem for some.
NAC is a good antioxidant, but not very efficient at increasing glutathione. I believe that Amla may be more effective for that purpose and it offers a myriad of other health benefits as outlined here :
healthunlocked.com/parkinso...
If memory, depression or anxiety is an issue, LO may be worthy of consideration, as outlined here:
healthunlocked.com/parkinso...
Art
Thank you so much. I have Amla in my notes to look up.
I’d like to give her LO but she’s on 50mg of zoloft and 7.5mg of remeron. I don’t think they can be taken together.
Yes, probably not compatible with LO.
Here is a link to a meta study discussing the benefits of omega 3's in AD and PD :
ncbi.nlm.nih.gov/pmc/articl...
Art
Thank you.
I definitely agree.
Do you know of an omega 3 to recommend?
I have Nordic naturals that I take.
I think that is a good one, but the daily dose may be on the low side. If you look at omega 3 / fish oil studies, they will often use more than that recommended on the label.
Art
What do you think about this supplement
naturalstacks.com/products/...
I think it is expensive for what is in it. I also notice that they make it hard to see what is in it because their magnification level is relatively low compared to other suppliers I have looked at and I think that is not by accident.
Vitamin C - 500 mg
Vitamin B-6 as P5P - 5 mg
Folate - 1 mg in a form that I can not read due to poor magnification
Vitamin B-12 as methylcobalamin - 4 mg
L-Tyrosine - 650 mg
Trimethyglycine - 600 mg
L-Phenylalanine - 500 mg
Another point to consider is that the bottle contains 60 capsules, but it takes 3 capsules per serving according to the label. That means that the bottle will only last 20 days ($40), so a one month supply will be over $60 and to me, for the above ingredients, is expensive. People report benefit from L-Tyrosine alone for PD. A good B-Vitamin multi will have B-6 (as P5P, a better form), B-12 (as methylcobalamin, a better form) and possibly the 1 mg of Folate in it. The L-Phenylalanine may or may not help with absorption. Trimethylglycine is fairly inexpensive and I'm not sure that 500 mg of Vitamin C is enough to make a difference as I would think that 1 gram would be a minimum amount to have any effect at all.
Art
Thank you for all your help
When are you going to be qualified for the PD?
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Which Vitamins/Supplements are essential for PWP.......... I know everyone’s needs are different but....
What are the most promising drugs/treatments on the horizon for PD symptom relief,slowing progression?
PD research: What is the problem?
