According to the following studies listed below, Amla, which is also known as Indian Gooseberry, shows the potential to raise one of the bodies natural and highly potent antioxidants, glutathione by approximately 50%+ in 12 weeks of daily use.
I'm posting this for the second time because HU deleted the first post with no reason given so this time it will not be written exactly the same as the first post, but will still convey the same useful information. Over the past 3+ years, many forum members have expressed a keen interest in the use and benefits of GLUTATHIONE (GSH) as it may be beneficial for PWPs and other neurodegenerative disorders. The problem is that many of the current methods of increasing GSH are cost prohibitive, inconvenient, ineffective or simply not practical for regular use, but the common herb called Amla Extract may be a good alternative option.
Although increasing Glutathione by 50% or more is a very significant and useful feature of the common herb called Amla or Indian Gooseberry, Amla is capable of much more in terms of benefits to human health and Amla extract is a relatively inexpensive herb that is readily available from online supplement suppliers at a reasonable cost!
Other important health benefits associated with Amla include a reduction of high blood pressure, triglycerides, atherosclerosis, total cholesterol, very low density lipoprotein cholesterol (VLDL), LDL cholesterol, inflammation and all while having the ability to raise the good cholesterol, HDL! The health benefits, of which there are many more, don't stop there, but for the purpose of this post, the studies I will link to highlight the above listed health benefits of Amla.
The following randomized human placebo controlled double blind study describes some of these benefits :
The following placebo controlled double blind study expands further on the above mentioned benefits of Amla extract while not reducing CoQ-10, which similar acting statins are well known to reduce CoQ-10 :
This next full study shows that Amla suppresses abdominal fat while having anti-hyperlipidemic qualities as well as having the ability to effect glucose homeostasis :
There are other health benefits associated with the daily use of Amla and a quick search of research on Amla in that area will quickly give you an idea of just how versatile and useful this herb is while having a very good safety profile, being relatively inexpensive and readily available through online supplement suppliers!
Here is a link to the product that was used in many of these studies called Capros and this is the 500 mg aqueous extract :
Lastly and importantly, it is probably important to point out that not everyone responds the same to prescription medications, supplements, vitamins or herbs and Amla is not an exception to this rule, but in almost all instances, trying is the only way to find out if the substance will help the individual or not as the studies suggest to be the case and that is what I an doing! Please check with your doctor to make sure this will be safe and compatible with the medications you are taking!
Art
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It looks like you cut and paste from another HealthUnlocked post, and the actual links were not preserved.
If you'd like to fix this, it's is possible to edit your post. At the bottom of your post, you will see the Reply and Like buttons. To the right of that, you can click on More, and then Edit.
That was odd, those links came from the actual web page as I no longer had them since the original post was deleted so I had to locate them again. In any case, they should be working now.
Hi Art as usual, very informative write up /topic - on a different note, I have been looking for a review of HOWARD SHIFFKE's protocol - RECIPE FOR RECOVERY ...can you help please
Okay, I just watched 5 of his videos. I don't have PD, so I can't test his exercises out to see if they do what he says they will do, but anyone with the symptoms that he mentions would be able to test his exercises very easily and quickly. The exercise for tremor alleviation would be very easy to do and test and would have large appeal to any PWP with tremors! If they work as he states, then I would definitely use them and that would be plenty of incentive to research him further. The exercises he shows can potentially be done by people with more advanced symptoms and in this sense, that aspect of his exercise regimen, will make it more appealing to a larger PWP audience!
What everyone pretty much universally agrees to is that exercise is one of the most beneficial things a PWP can do to help slow disease progression. This is great for many PWPs, but if the exercise is such that only people in stage 1 or stage two are able to do them, then not much help for people who are at a more advanced stage, but his exercises look easier than many I have seen and could potentially be done by more PWPs who are at a more advanced stage of disease progression and that is a very good thing in my opinion.
On a related note, if he is correct about what he is saying, then I would fully expect mag oil to be synergistic with his exercises. Mag oil works very well to loosen shoulder joints and muscles while having an anti-inflammatory effect. and pain relieving effect. The benefit of mag oil will be very easy to test in conjunction with his method. Using his very simple exercise for hand and arm tremor, apply mag oil to one shoulder and surrounding area only, before starting his short and simple exercise. If the mag oil seems beneficial for the one shoulder that you apply it to, then you know that the mag oil is worth applying before starting his exercise. I think that mag oil may also make it possible for more PWPs to use his exercise because of its pain relieving, muscle relaxing and ability to loosen joints.
That would be my take on what he is doing.
Btw, I will not answer any more questions in this thread that are off topic like this so that the thread can stay on the topic of Amla, which I feel is also important for the forum members.
If possible, could you please start a new thread about Howard Shifke's Protocol, because after watching those videos, if his easy and simple exercises actually do what he says they can, in terms of helping with tremor of hand and tremor of arm, writing, shaving, brushing teeth, eating with fork or spoon without spilling , voice softness, balance and improved walking . These exercises are very easy to do compared to many exercises I have seen by others. That means that even more PWPs would be able to do them even at more advanced stages of progression and that is a very important point! His YouTube videos are short and to the point !
By you creating a new thread that can be searched for on its own, it will be easier for other members to find and I believe if these simple and easier exercises work as he says, this will be very valuable information to many other forum members and visitors!
Art thanks for your nice mail but I may not be of much help as I dont know how to create/manage a new thread ....can participate in the conversation only ...so help needed btw I think you have not yet seen his main item viz ..PARKINSONS RECIPE FOR RECOVERY......a detailed 2 to 3 hour program that is supposed to halt / / cure PD...... it is a combination of QI GONG exercise ,meditation, affirmation, diet etc ..... he calls it HEALING OF SOLE ,MIND & BODY.....in the testimonial section ....names of PWP s recovered / recovering are given....think -its worth reviewing by forum members
In one post Howard speaks of Yin Tui Na ( Forceless Spontaneous Release), same as recommended by Janice Hadlock. I believe it is the only common element in both protocols other than no PD medicines allowed in both protocols
Good post. I am already giving Amla to my mother on a daily basis - since more than 2 years, in addition to Turmeric, Ginger, Cinnamon (Ceylon). Also giving CBD+THC combo, NAC 500mg/day, Thiamine 500 mg /day. Now planning on giving Symprove (probiotic)
Sounds like you chose some very good supplements to give your mother! Are you seeing positive results? Taking amla orally seems like I might have some difficulty as the smell when you open the bottle is a bit strong and for me, not in a good way. I guess the cinnamon would help a bit.
I have been testing Amla for several months to control my blood pressure and it works quite well for me, but that does not mean it will work for everyone the same. That is just the nature of supplements and meds. The only way to find out is to try it. I'm glad I did because the Amla has replaced three other supplements I was taking for that purpose and it offers so many other potential health benefits too!
I buy the raw fresh frozen amla from the Indian Groceries store ( as in India); typically Patel Brothers or any Indian Grocery store should have it in their frozen section -either the whole fruit or one without seed. The powdered form is also good but I am not sure if it is adulterated. She has not deteriorated much during these 2 years. Stopped giving her Bullet Coffee - too much fat for her who is not very physically active all day.
Thank you for the reply! In the studies that I linked to, they used the extract version of Amla and so did I. Compairing it to turmeric/curcumin, I believe turmeric has its benefits and curcumin has its benefits, but I doubt that they are exactly the same benefits. Most cancer studies are based on curcumin, not turmeric.
As far as I know, Amla may be the same in this respect and I don't know if the powder would have the same effects as the extract. I have not used the powder or non extract versions of Amla so I have no idea about if they are comparable in their effects.
Curcumin is considered to be the active medicinal component of turmeric(the herb) in a similar case of EGCG being the active medicinal component of tea. Curcumin is available from all major supplement suppliers online. Here is an example :
I'm not recommending a specific supplier, but all major online supplement suppliers carry it. I just make sure that it is "amla extract" and I use at least as much as was used in the studies that I linked to. Here is a link to amazon for "amla extract" which list many suppliers :
I have only used the "extract form" as that was what was used in the studies and the non extract forms may not be as effective. I am trying to replicate the study results and they used the extract form so I did too. If you would like to use the same brand (Capros) as used in the study, here is a link to that brand of 500 mg capsules of Amla :
I have not experienced these three effects in myself nor anyone I have recommended it to nor did they mention any of those side effects in any of the study participants at the doses used.
Amla, in the juice form is purported to aid in weight loss, but I have not seen this effect from the Amla extract capsules in myself, but my sister has reported weight loss after being on Amla for about 9 months. She told me the other day that she has been losing weight while on Amla. When she comes and stays with me, she can hold her weight or even gain a little, but we eat pretty hearty when she is here visiting.
Thanks Art, Actually for me is reducing weight is ok but for sibling is much concern as she is already has on low weight. She is taking 500 mg one time only for 2 months already. I think Amla is giving appropriate outcome as overall performance. I am using powder form buy from Indian shop near me.
I would also appreciate if could find a shop online for my other meds, shipping to Pakistan. previously you mentioned vitacost.com but now they've excluded Pakistan from their export list. I wonder if you may be again helpful to find some? Need to order my meds i have only few in stock remain.
I have suggested this supplier and they seem to ship to more countries than any other supplier and they show the flag of India in their countries listing. They are located in the US.
Has been close to 5 weeks now since I started giving Symprove to my mother. I would say marginal improvement in (mainly mood and general well being) and to some extent in the bowel movement - which was more or less Ok even prior to taking Symprove. I am planning to give it for a total of 20 weeks (or end of year) so as to give me enough time to make a decision about continuing or not. Hopefully it will help her even more as time goes by.
I am only trying to do my duty as a son. Wish I could do more and not go through the pain of seeing my mother suffer 24x7 and being helpless while I can only watch. The physical labor and stress thrust upon me is nothing - it comes and goes away with adequate rest - compared to the mental agony of seeing her suffer. Sometimes I think (philosophically of course) that it would be better for her to leave this world and be in a happy and better place) than endure all of this meaningless suffering. Do not mistake me, I love my mother, but her pain and suffering all day makes me cry (I do it a lot when I am by myself and alone, when she sleeps). I pray to God that at least he give me instant and painless death, rather than prolonged suffering. That being said, I am literally by her side 24x7 trying and testing something new with the HOPE that she will get better... Aaahhh I can hear my maker laughing at my human instincts!!
You are a wonderful son to help your mother through this very difficult time in her life! I’m sorry that it causes you such pain, it can be agony and exhausting to care for and watch those we love suffer! I hope you are able to get a moment to yourself dr
I just read about your mother and the everyday battle you are waging. (I can see my mother all over in your post). I know that even saying that I feel sorry is no solace. This is a real test of life and courage, knowing that we are fighting a losing battle makes it hard; Hoping for the best and we need a miracle ASAP for all who are battling this disease and other CNS diseases.
Again, I'm really happy that you have reposted this. Thank you.
I have messaged Jennifer and Helen, the two administrators with recent activity, asking them not delete this post.
Seeing it now, I do recognize its value. I also may have some insight as to why the previous instance was deleted.
First of all, the title is in all caps. Second, it appears vaguely similar to a spam title. ("THIS HERB IS SO AMAZING!!!! IT WILL CURE EVERYTHING!!!")
Maybe the herb does have a lot of health benefits. It is said to be the most revered in Ayurvedic medicine, so it probably does. Furthermore, I am not defending the removal of your post by the administrators, and I do not ultimately think they made the right choice. Rather, I'm just trying to find an understanding of why they did, and help you and other people avoid having their posts removed in the future.
On a more nuanced (but still important) point, in my initial review of this, I've already found that you made one moderate overstatement.
Your title suggests that Amla can increase glutathione levels by 50% for anyone. But the research that you cite does not say this. They found a higher dose of amla increased glutathione levels by 50% ***for a group of people who had endothelial dysfunction***. These people may have an extremely low level of glutathione in the first place. We cannot assume that just because THEIR levels increased by 50% that EVERYONE'S levels would increase by 50%. Interpreting science requires that we be very careful about our statements.
I still think this is potentially quite relevant for people with Parkinson's. I'm glad that it's here. I hope you don't take what I'm saying harshly. Your presence and contributions are very valuable, and I hope I'm being helpful and constructive. I want to encourage you. I want to hear more from you. Thank you for your effort.
I have had many posts on this forum using all caps in the title without a problem, but that was awhile back and maybe things have changed. If I get more deletions though, I won't post any more because it is a pain having to repost. I am merely highlighting an herb which I feel may have value for some on this forum and Amla appears to be very versatile for different health issues such as macular degeneration in addition to the above listed items in the links, but there are no guarantees that it will work the same for everybody. If a pesrson is interested in Amla, then it is up to them to do as much research as possible.
I am using the Amla for the specific purpose of controlling my blood pressure and it is working effectively for me for that purpose. It has many other potential health benefits and it will just take some reading and time to find out if it is something worth considering. I took the time and did the reading and decided to try it for my purpose and am very glad that I did!
I have never seen a study where both NAC and Amla are studied as a combination together, but both are fairly potent antioxidants. I've used both myself, but not together, so I can't give a good answer to your combo question.
The NAC, I have used in conjunction with arginine to control blood pressure and it worked well, except that it soon put my lysine / arginine ratio out of balance and I found myself catching colds non-stop which required having to take lysine also to put that ratio back into balance. This trio worked to control my blood pressure, but was kind of a nuisance to have to take all three just for blood pressure control. So switching to Amla made sense for me as it works as well or better than the trio and offers more potential health benefits so I will gladly stick with Amla over the trio.
I know that NAC is considered to be a glutathione precursor, but there do not seem to be a ton of studies to confirm that it boosts GSH by much in the brain , where it would be most useful to PWPs and I would think from the studies, it might require well over 1,000 mg per day to get any glutathione boost benefit to the brain. Here is a link to a study which I think is more typical of the majority of studies using NAC as a way to boost GSH in the brain.
Notice the dose used in this study is 6 times what you are currently taking and yet it sounds like the glutathione boost in the brain was negligible and at that dose, I think adverse events could easily become an issue. When I tested 2,400 mg /day on myself for over a month, I started having gastric issues and apparently that dose would not be enough to boost brain GSH. I think NAC, because of its relatively low absorption to the brain is of limited benefit for that purpose.
That would definitely explain why I started having digestive issues at 2,400 mg/day. In the one study I linked to on NAC, they used a 6,000 mg dose once per week, but it was injected and then they had a daily oral dose too and still they did not get the response they were looking for in the brain as far as a very significant increase of glutathione in the brain. Blood is some where in the 7.1~7.3 ph area, so 6 grams of acidic NAC must take a significant bight out of our bicarbonate stores.
There is little doubt that when NAC can end up getting significantly more GSH to the brain that it will be very beneficial, but so far, at the doses that might be needed to accomplish this feat, there will likely be adverse events which may make continued use all but impossible. For the purpose of increasing glutathione and catalase very significantly in other parts of the body, it may still take a very high dose, high enough to potentially cause adverse events. Many studies are in vitro or animal studies and what would equate to very high doses of NAC are used directly in a test tube or at very high dosing schedules in animals, but this is not equivalent to what maximum doable human dosing can do in the body.
I think there is a form of NAC that may be more bioavailable, but it does not seem to be readily available or inexpensive.
Thanks for giving me your thoughts on NAC. I've been revisiting articles on NAC for the past few days, it can be pretty rough on ones stomach...BTW...I originally got on the NAC, and other amino acids to ' feed my mitochondria ' for energy to get through the day.
I mentioned in the original post above that Amla can be useful for many health issues like high blood pressure, high cholesterol, high triglycerides, arteriosclerosis, potent antioxidant, increasing plasma glutathione significantly, suppression of body fat and age related macular degeneration, but the potential health benefits do not stop there!
In the following double blind, randomized, placebo controlled study, Amla has also shown the ability to help certain digestive issues such as non-erosive reflux disease (Nerd) :
Having the availability of one supplement that can help in multiple health issues is a definite advantage for us as having to take only one supplement instead of four or five different supplements in order to alleviate symptoms is much easier and less expensive! Also, I think that many of you may find, as I do, that it is harder to stay on a specific supplement regimen when it requires that you have to take four or more supplements as opposed to only having to take one supplement. Also interesting in this study is that they used twice as much Amla per day compared to the studies above suggesting that Amla can be effective at multiple dose levels and is fairly tolerable even at higher dosing! Taking small steps to make life easier for ourselves is useful!
Amla fruit is the king of whole food antioxidants, boasting more antioxidant power than any other in-tact whole food. These gooseberries are abundant in India, and are an antioxidant powerhouse that modern medicine is only beginning to understand.
To gain some perspective, whole Indian gooseberries contain 75 times the antioxidant power of goji berries, 60 times the antioxidant power of pomegranate, 50 times the antioxidant power of raw blueberries, 13 times the antioxidant power of black raspberries, 2.5 times the antioxidant power of acai berries, and 2 times the power of ground turmeric.
That is really great information and thank you for sharing!
I think once people start looking at the many studies on Amla, they will wonder why they have not heard more about it! It's one of the really good ones and it has so many more potential health benefits than the significant number mentioned above!
Hi Art, first of all, thanks for re posting it really worth it and a big help for remain folks in budget and top of it to remain for medicine selection/ reduction to have only one substitute supplement. Your efforts in making ppl life easier is much appreciated.
I am in symptoms since 2016 and my age is 43. I was first examined in 2015 upon my physical symptoms (balancing, coordination and walking) review by a senior neurologist.
Two months before i started new meds (l-dopa/c-dopa/Entacapone) 100/25/400mg per day inclusive if Q10 x 200 mg per day.
Apparently having mainly balancing, limb stiffness and wobbling movement issues. Above meds are giving initial support to live with but on the other side have impression of vertigo, memory dimness etc.
I am hard hunter of finding natural way of heeling instead bundling medicines for every cause. Even want to remove my current medicines regimen and fall 100% on natural sources. Though i am tasking very light doses.
I hope AMLA could be of good to add regimen. I will give it a try and shall revert upon out come after specific period.
To further illustrate the potential of Amla extract, researchers are just now starting to study the effects of Amla in neurodegenerative disease including PD. Here is a recent PubMed abstract that briefly discusses this subject :
"Both aqueous and alcoholic extracts of amalaki [amla] inhibited activity of rat liver glutathione S-transferase (GST) in vitro in dose dependant manner. Since GST acts as powerful drug metabolizing enzyme its inhibition by amalaki offers possibility of its use for lowering therapeutic dose of herbal preparations."
I wonder whether this is actually a good thing, or if it is preventing glutathione from doing one of its functions. It looks like the enzyme GST helps glutathione with cell detoxification. "This activity detoxifies endogenous compounds such as peroxidised lipids and enables the breakdown of xenobiotics." Wait a minute. I WANT to detoxify peroxidised lipids.
I'm not taking amla to block glutathione. I don't want to artificially "raise" glutathione levels by blocking its effective use.
It is not entirely unusual to have contradictory findings. I'm not dissing amla or saying it's not good. But I'd sure like some more information.
Last paragraph of the article:
"Inhibition of GST activity in dose dependant manner by amalaki extracts is worth while to be explored because this enzyme acts as powerful drug metabolizing enzyme by its conjugation reactions with glutathione (39). Inhibition of activity offers a possibility of combining amalaki with drugs to enhance their potential in case of drug resistance or reduction of dose. Various Ayurvedic formulations use amalki as main ingredient of three herb preparation called triphala and mainly to enhance therapeutic value."
A 35% extract is fairly strong and treating cells directly is not quite the way it would be in the human body. Amla has a very long historical safety profile at the dosages used in the human studies. I take a little more than the higher dose study and find it quite useful, but of course I am not tracking the anti-atherogenic effects which I would be quite happy to enjoy as time goes by! I consider the many other potential health benefits a big bonus from just one supplement! I like multifaceted supplements that are capable of more than one benefit because it just makes life simpler and easier!
This isn't a human study, but it attempts to illustrate that Amla has potential to enhance Mitochondrial Spare Respiratory Capacity by Increasing Mitochondrial Biogenesis and Antioxidant Systems.
A very important occurrence in seniors trying to withstand the many oxidative challenges associated with PD throughout the body. There may or may not be a human study later to confirm, as there are already rodent studies which do confirm, but knowing that Amla is a very potent antioxidant from previous studies is definitely a step in the right direction! Here is a link to the full study :
Dr. Mischley prescribed intranasal glutathione for my husband, especially for his lack of energy after his recent stent procedure. He is about to finish that. I will email her with a link and ask her opinion.
You are a valuable member of this forum--can't do it without you!
I didn't really go over this in much detail regarding Amla and its antioxidant potential, but it also increases production of some of the bodies other potent antioxidants like catalase beyond being a potent antioxidant of its own! A very important point with Amla is the broad spectrum of medical uses for multiple disease states. The available studies do not fully cover all of the medicinal possibilities with Amla, but if you read the available studies and understand some of the methods of action of Amla, you can just let your mind wander through other health issues and realize that Amla is likely to be much more useful in many more diseases than the current literature has even begun to cover and then you also have to include the fact that it is a very potent anti-inflammatory and much more with a very good safety profile!
Here is a very brief abstract about Amla that mentions only a few, but gives a huge clue as to just how broad the coverage potential can be! :
Just a thought, Despe, but maybe you can ask Dr. Mischley if it would be helpful to run Amla alongside the intranasal inhalations of glutathione to try and maximize his glutathione levels as quickly as possible. That may likely involve either the highest dose used in the studies or possibly more depending on what Dr. Mischley thinks. This Amla is no joke and it would be a mistake to just assume that Amla is just the same as other herbs, it is much more than that! The anti-inflammatory effects are not going to hurt his cause either!
I did ask Dr. Mischley to check on Amla. Was not aware of it, she said she would look into it and let me know. Before the consultation, I emailed her the links you had provided. See what she recommends.
One of the reason's I did this post was because of the mentioned benefits of amla for the multiple health issues mentioned above, but another reason is because those links give a decent idea of how potent an antioxidant and anti-inflammatory amla is also.
When you look at what inflammatory mediators amla impacts on and then compare those to the inflammatory mediators that are known to be at elevated levels in PD, you can get an idea of what I am thinking. The same goes for amla's potent antioxidant properties and relate those to the elevated oxidative stress and free radical damage from multiple types of radicals with PD and again you can get an idea of what I am thinking.
I am currently using amla as part of my regimen to help control blood pressure as well as excessive inflammation and oxidative stress and I believe it is working well for my purpose.
I hope that Dr. Mischley does enough research to understand the true value of this very versatile, potent and readily available herb!
Art, haven't heard from her yet. If she doesn't reply within 2-3 days, I will follow up with a "gentle" reminder. I just couldn't wait though so I ordered Amla powder on line. I would have ordered capsules. Oh, well.
I ordered "amla extract" in capsules as that is what is used in most of the studies. I'm thinking the extract may be stronger than the powder form in some respects, but I am not positive. Since I was trying to replicate certain aspects of the studies, I thought that I should try and use the supplement in a form that is as close as I can get to the studies.
I often forget that some members are unable to read these studies for various reasons and since that is the case sometimes for some members, I want to mention a few other things regarding the study that was specifically looking at glutathione / amla that I feel are very important and I should have mentioned them in the first place!
In that study, it was shown that the higher dose treatment group (1 gram total per day)was able to raise their serum glutathione by more than 53% in just 12 weeks of supplementing and that is impressive on its own, but the study went on to show other impressive results which I may not have mentioned, but should have.
One is that amla itself is a highly potent antioxidant and is easily in the top 10 category of herbs for this purpose.
Two is that amla is also able to increase other potent and natural antioxidants of the body such as catalase and others.
Third is that in the study, amla was able to decrease high sensitivity C- Reactive protein (hs-CRP) often used as a biomarker for global inflammation in humans. Many supplements and herbs are capable of reducing hs-CRP, but in this study, amla was able to reduce hs-CRP by greater than 53%! You may wonder why this is important in PD and the reason is that in PD, hs-CRP is very significantly elevated and lowering chronic inflammation is generally a very good thing for our health!
Fourth is that this same study also showed that amla also lowered malondialdehyde (MDA) which is often times used to show damage caused by free radicals. MDA is not necessarily
elevated in PD, but lowering the MDA value is suggestive of reduced oxidation and radical damage and increased total antioxidant capacity, which would be important in many disease states including PD. Amla was able to lower MDA by over 30% in just 12 weeks!
I was just reading a human study discussing use of oral glutathione(GSH) supplements. In this study they used a low dose of GSH (250 mg / day) and high dose GSH (1,000 mg / day). At the end of 6 months of daily supplementing of 250 mg of GSH and 1,000 mg of GSH, the increased blood level of GSH was 17% in the low dose group and 30 ~ 35%. Here is a link to an abstract of the study :
I Just wanted to post this to give something resembling a basis for comparison to the amla study which was able to exceed 53% glutathione in half the time at the same dose of one gram / day for glutathione or amla. The other consideration is the multiple other health benefits associated with the amla study!
Hi Art, I recently started Acetyl L-carnitine (ALCAR)-1000mg+ CoQ10-200 mg and C/L 25/50 x day. Please help to have recommended dose for Amla extract to add my daily regimen. Would appreciate.
If you are trying to replicate the results of the study then I would use what they used at the dose they used. They used "Amla Extract" and they used 500 mg twice per day for a total of 1,000 mg per day. One of the studies used 2 grams per day total, but you would have to go back in the links in that post to see which study it was.
To add a liposomal form of glutathione (LG) for comparison, I found another study that used LG at one gram per day also. It has been my experience that liposomal anything is generally not inexpensive, but this is useful for the sake of comparison to the amla study also. In this study they used 500 mg / day (low dose) and 1,000 mg / day of liposomal glutathione. A major difference in this study is that it was only four weeks long. Interestingly, it appears that this liposomal form showed a peak in blood level at two weeks in the low dose dose group (>+40%) and then declined into the 4th week of testing. By the fourth week, the blood GSH had declined from the second week high results.
In any case, it appears that amla may have outperformed the liposomal glutathione by reaching a significantly higher percent change, however a direct comparison is difficult given that the amla study was 12 weeks long compared to the Lipo-G study which was only 30 days long, but it appears that glutathione peaked at two weeks in the Lipo-G study.
I have high BP. Not horrible but enough to have given me a mini stroke a few years ago. Anyway I don’t like BP meds. I eat right, exercise and have good weight but still have elevated or stage 1 BP. At Art’s recommendation I started on Alma about 2 months ago. My BP on average has gotten slowly lower. Nothing drastic but definitely an improvement! Just wanted to share. I will continue using Alma.
The health potential of amla continues to be exposed layer by layer as studies of amla are completed. In this new study, the potential of seven of its major components to act in an antidiabetic capacity are discussed.
What an interesting thread. Thanks! Amla and many other of the herbs mentioned here are commonly used in Indian cuisine. Do you know if there is a lower incidence of PD in the population there? I think PD and some other central neuro conditions (eg, MS) are more common in northern climates, so if it's lower in India, it may be something other than the diet. But I'm curious if there's any link to this particular diet that has been teased out from other variables.
The Parsi community in Mumbai has the world's highest incidences of PD where it affects about 328 out of every 100,000 people despite living in a country, India, with one of the world's lowest incidence of PD (70 out of 100,000). [3]
Yes, PD does seem to have a lower incidence in India.
Here is a quote from another article :
The prevalence of the disease ranges from 41 people per 100,000 in the fourth decade of life to more than 1,900 people per 100,000 among those who are 80 and older.
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