200 mg day, then 400 mg day of thiamine ; I'm PIGD
200 mg day produced mild improvements. 400 day seems to have an additional effect. My motor skills have continued to improve moldly: as if, as the thiamine-boosted mitochondria function better, some impaired neurons etc are slowly coming back to life.(?)
Mildly.
Excuse my ignorance. What is PIGD?
Postural instability and gait disorder
Postural instability means that you have a hunched back??
Mainly, impaired balance, many falls. Three required medical attention, including injury to cartilage of right patella. Broken femur. Also, cervical problems with disks, vertebrae. Curved spine.
I am happy for you.
This is nice news 
My wife has been on 200mg injection once a week for about a year now and has not seen any improvement, her balance is much worse and has had several falls, most recent a broken wrist, her speech somedays is non existent and her mood is very low, do you think she should up her dose of Thiamine?
I am not an MD. I am not familiar with her medical record. I am not in the position to make a recommendation.
No medical professional would make any recommendations without a lot more information.
The members of this website are very free with their advice and comments with no need for the full story,
You might explore this list's postings about orthostatic hypotension and posts about postprandial hypotension.
Guide: Files, Dose Adjustment
Diagnosed 2012
My regimen:
The positives: no bradykinesia, I cut my food with a knife, no button difficulties, brush my teeth now w/o needing elect brush, more strength. Getting in and out of bed, turning over is easier. No more constipation. Parkinson's progression stopped. Suppressed all motor and non-motor symptoms...
Entering my 7th year post diagnosis and have not fallen, not once, to the surprise of my neuro. Was seeing neuro every 6th month, last visit he set app one year. He said if needed we could do some changes earlier. He said my condition can change in as little time as one week.
New schedule, now I follow this regimen:
3 x day C/L 50-200 ER : 8 am, 2 pm, 8 pm. Because it is ER, I take with or w/o food.
2 x day (8 am 2g, and 2 pm 2g) Vitacost vitamin B1 (as thiamine HCL) 500mg, easy swallow capsules
B1 Thiamine therapy reference / stop progression, suppress motor and non-motor symptoms:
(Thiamine HCL is oral substitute to injecting B1) 2 x day (morning 2g and at lunch 2g)
Doctor Costantini strategy that I find helpful "thiamine hcl stops the progression forever...".
Parky people say the first five years is your honeymoon stage with Parkinson's. After that, progression more rapid.
I have gone from slow motion to normal motor action since joining the growing number of PwP that have started B1 regimen/protocol. –
Doctor Costantini - “Why is this? Because there is no medicine or drug that is able to affect all of the organs, whereas all of the organs function thanks to Thiamine. An important detail”, adds doctor Costantini, “the Thiamine therapy brings no collateral damage with time”.
Join my facebook group:
"parkinson's thiamine hcl"
facebook.com/groups/2322600... ; …
Parkinson's Relief, Questions and Answers
Guide:
1. Read page, About, open links.,
2. On Files page, open B1 FAQ document.
3. On Files page, download First Appointment document, answer and submit.
4. read Announcements
5. Website: Dr Costantini's guidelines on Parkinson
I’m new here, so correct me if I’m wrong. I believe the protocol calls for reduced dosage if the symptoms get worse.
That is my understanding, also. Everyone is different and depends on your weight, etc.
Me too x
Happy for you👏🏻💐🥂
Very happy for you and for B1.
B1 effect?:)
NAD, Thiamine (B1) and Day 63 of TTDF 7/18/22.
B1
