This is interesting. Mitochondria and stress, energy

[LAJ12345]

Part 2 of this mini series. I’m halfway through, it is quite good.

theenergyblueprint.com/mito...

PDF:

theenergyblueprint.com/wp-c...

[KERRINGTON]

Interesting...I liked part 1 more than I liked part 2.

[LAJ12345 in reply to KERRINGTON]

He does tend to repeat the basics too much then speed over the details! But the theory of hormesis is very interesting. It kind of eplains the decline in Parkinson’s I think, where lack of dopamine leads to apathy and the reluctance to do anything that stresses the body. My husband was just sitting or sleeping all day and I blame the antidepressants for that but I think that made him decline fast. It makes sense that by pushing yourself on all fronts it helps the brain repair. It must rebuild neural pathways too I think.

[park_bear in reply to LAJ12345]

Is not just the antidepressants - Parkinson's also plays a role. I call it "seductive fatigue" - I feel good just sitting - getting up and moving is work. Once I get moving it is okay but it takes an act of will.

[LAJ12345 in reply to park_bear]

Yes, but interestingly once he went off mirtazapine he was not apathetic at all, but unfortunately the anxiety took over.

[TeUruraki in reply to LAJ12345]

LDN - Low Dose Naltrexone is a great option for some. lowdosenaltrexone.org

Prescription required.

Lithium Orotate for depression is an option. Non prescription. iherb stockists KAL, Lithium Orotate, 5 mg, 60 VegCaps NZ$7.03

psycheducation.org/treatmen...

verywellmind.com/the-benefi...

[KERRINGTON in reply to LAJ12345]

Now, for me, just writing my name takes up all my energy.

[LAJ12345 in reply to KERRINGTON]

Yes he does get tired quickly still. So we will try and see if any of these tricks work for that!

[PNIAuthor60]

Thanks for the resource, I appreciate it as it is also relative to my diagnosis of chronic fatigue.

In fact a Professor who was a cell biologist explained it to me that my own diagnosis is a dysfunction of the mitochondria in each of my cells, including their brain cells and neurons.

Mitochondria are the cell's powerhouse, the source of cellular ATP energy. In CFS the mitochobdria are simply not producing enough ATP to meet all of the energy demands of the body.

Amazingly, as much as 2/3 of our ATP energy is used to simply keep the body alive and "idling" ( think about being asleep and not moving) and more may be produced if the person moves a lot or is athletic.

70% is used just to sit there, doing nothing. Of course, if we are thinking, we are using lots of ATP.

Exercise builds up the efficency of the supply of energy when needed, including when we are thinking and making and suppressing memories - I believe PD has a cognitive component as well.

[TeUruraki in reply to PNIAuthor60]

LDN - Low Dose Naltrexone is a great option for some.

lowdosenaltrexone.org

bmj.com/rapid-response/2011...

Prescription required.

Lithium Orotate for depression is an option. Non prescription. iherb stockists KAL, Lithium Orotate, 5 mg, 60 VegCaps NZ$7.03

psycheducation.org/treatmen...

verywellmind.com/the-benefi...