nature.com/articles/s41531-...
I had my nasal microbiome checked and I have some nasty bacteria in there. The study doesn't mean fixing it after the fact can help, but maybe so? Exposure to mold can mess up your sinus microbiome big time.
I'm currently using a probiotic for the sinuses, Lanto Sinus.
I just happened to see this after reading your post. Very interesting.
Well that is a great find rebtar. Depressing. One more thing to try and tackle. But great.
14 years ago I used to get migraine headaches at least once every 10 days. I actually had to plan my projects (I was a PM) taking into account I was going to miss days of work. I got a MABIS Facial Steamer amazon.com/gp/product/B000A... and started breathing steam and my migraines went away. Went away for good.
Did I do damage with the steamer? Or should I start steaming again? Or is this correlation without causation?
Thanks for sharing this. It helps.
You can do nasal rinses with a neti pot or Neilmed type product. But a nebulizer like NasoNeb does a better job I think. It's not steam (hot -- could damage sensitive mucosal tissue?) but a fine mist. Although with your product perhaps the steam cools enough before entering your nose.
In any event, I think it's worthwhile using distilled or boiled and cooled water, and making an isotonic saline to go up your nose rather than using regular tap water. I used tap water previously (a previous doc thought it didn't make a difference), but I bet chlorine isn't something your nasal microbiome appreciates.
Thanks. That steam gets way up in the nose. No idea if it is bad or good (except it fixed my migraines).
I tossed it when I almost died of the flu a couple years ago. I got some lung scarring.
I'd probably lean towards the nasal probiotics now. But I need to spread these things out.
Probiorinse™ Nasal and Sinus Irrigation Solution with Probiotics
This looks the best of what is commercially available:
ncbi.nlm.nih.gov/labs/pmc/a...
Conclusion
Topical intranasal administration of live L. lactis W136 for 14 days in patients with chronic rhinosinusitis refractory to medical and surgical therapy was well-tolerated, without serious adverse events or new infections. Improvements noted in symptoms, quality of life, and mucosal aspect suggest that topical administration of Lactococcus lactis W136 may potentially represent novel alternative therapy for patients with sinus disease, making it worthy of further investigation.
Friendly nasal bacteria may protect against sinusitis
A bacterial strain adapted to life in our noses may help prevent the painful, chronic inflammation of sinusitis. This discovery could lead to the development of a probiotic nasal spray to treat the condition. medicalnewstoday.com/articl...
“Friendly bacteria” from the genus Lactobacillus are known to have beneficial effects in the gut, genital tract, and skin, where they protect against infection and modify immune responses.
Lactobacilli are rod-shaped bacteria that ferment sugar, producing lactic acid as a byproduct, which can inhibit the growth of other microorganisms. This type of bacteria usually prefers to grow in conditions with either no oxygen or tiny amounts.
They used Lactobacillus casei, strain AMBR2 in their study.
This is as close as I can find to what they used: amazon.com/Lactobacillus-Pr...
Or this. It is cheaper. Still not the same strain: amazon.com/Probiotics-Billi...
Lactic acid bacteria as probiotics for the nose? sfamjournals.onlinelibrary....
sciencedirect.com/science/a...
From the 100 healthy volunteers sampled, nine isolates were obtained, whole-genome sequenced. and classified at species level as L. rhamnosus, L. casei, L. sakei, and L. plantarum. Of note, these taxa were also found to be among the most abundant Lactobacillus ASVs based on the microbiome profiles (Figure 1E). Six L. rhamnosus strains were isolated (L. rhamnosus strains AMBR1, AMBR3, AMBR4, AMBR5, AMBR6, and AMBR7), one L. casei (strain AMBR2), one L. sakei (strain AMBR8), and one L. plantarum (strain AMBR9) (Figure 1F).
I take a few things from this article: sciencedirect.com/science/a...
1: You don't have to put the probiotic in your nose for it to get to your nose. Mouth and nose are connected.
2: L. plantarum (strain AMBR9) does not seem to colonize long term (but may impact other bacteria long term?).
I know the one I'm using isn't cheap. But my doc recommended it and she does extensive research on the products she recommends. And considering how involved the nose is in PD, AND that I've had nasal congestion for years (with a couple bouts of sinusitis after a really wet winter where I found mold growing on the back of my cellular shades -- yes, dumped), I think it's good investment.
My doc recommended using NasoNeb to get it way up into sinuses, which isn't always easy. My sinuses are clearly inflamed, because the first few uses the liquid turned pink (warning: ick factor coming!), which meant that my nasal mucosa were bleeding and it was dripping back into the solution.
Working hard on getting out of this moldy house! Six months max (keeping my fingers crossed).
Have you got an air filter. If you can’t move out maybe you can at least filter the air you breathe. I got hubby one of these philips.co.nz/c-p/AC2887_70...
Thanks, I’ve got two good ones going upstairs where I spend mist of my time, and one downstairs. Plus a dehumidifier. It does make a difference.
May I ask which nasal probiotic you use and where you buy it? I have no experience with this. Your doctor sounds great. I wonder if she takes long distant patients. I’m in NC.
I recently read about toothpaste and dental products intended to address the oral biome. They were recommended by Dr. Bredesen
It's called Lanto Sinus (L. sakei). NasoNeb works great for this. Buy online. I believe my functional medicine doc is not taking new patients. I can ask. She does all appointments online at this time. Warning: good functional medicine docs are expensive. I don't see her very often!
You can look into these functional medicine practitioners in North Carolina! I'll ask my doc if she knows someone over there.
Just confirming?
Yup. My doc said to get two bottles. Use twice daily. Instead of using the instructions from lanto you can use the same amount suggested in divided dose morning and evening using NasoNeb. It takes a bit of getting used to but after a couple of days its easy and quick.
And taken via inhaling with this device? I appreciate your help!
I’ve been seen by two different functional medicine doctors. One was Dr. Todd LePine who works with Dr. Mark Hyman. I expected more. He seemed a bit ambivalent. Any recommendations would be great! I’m new to NC.
I’m happy to have another means of caring for my health so thank you for sharing this nasal knowledge!
An interesting interview with Prof. Sarkis Mazmanian (Caltech) regarding the gut microbiome (and PD)
Kiran krishnan microbiome products
Would you recommend Gut Microbiome Testing?Recent gut-microbiome paper: Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms (Nov 2022)
Bacteria and Brains: An Interview with Microbiome Expert Sarkis Mazmanian
