Just posting link to article, I found it interesting and hope you do too.
Ivermectin and neuroprotection: Just... - Cure Parkinson's
Ivermectin and neuroprotection
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goldiewan
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biorxiv.org/content/10.1101...
This is a mice study
Yes, mice.
But it would be better to characterize the experimental procedures in this paper as cell research.
The study primarily involves experiments on brain slices to investigate the effects of ivermectin and L-DOPA on dopamine release.
These procedures involve cellular and molecular techniques such as fast scan cyclic voltammetry and electrophysiology, which are typical of cell research.
Insight from a ChatGPT query of the paper. ✨🥂✨
But mice cells are not human cells, even if they are similar 🙏
We are all looking for stuff to help in the here and now. But that does not mean we have to dismiss mice studies. This is the first stage of any exploratory attempt to get to the core driver of this ailment.
The choice of C57BL/6 mice is significant because they provide a reliable model for studying neurological functions and diseases, making the results more robust and reproducible.
The use of MaFIA mice is crucial for understanding the role of microglia, the brain's resident immune cells, in mediating the effects of ivermectin on dopamine release.
These models help bridge the gap between cellular mechanisms and potential therapeutic applications for human neurological conditions.
And there is someone in the community who is using this drug. The information gathered in this mice experiment may give some insight as to how the drug works for her 🌺
hopkinsmedicine.org/news/ne...
Exercise (even above diet) is the main thing stated by neurologists when you walk in to their office today to slow progression. Was it based on human trials? Most all drugs, small molecules,etc are tested on mice first. The cost involved in human clinical trials is astronomical and will most likely never be done for IVM and PD. There is no financial incentive for an off patent generic drug for biotech or pharma companies.
There is ample research on exercise benefits in humans.
I am not questioning the mice research, just that mice data extrapolated to humans is a very crude method. The cells are inherently different, in function, size, shape and DNA.
I have in the last 4 years, chased every supplement deemed beneficial in mice studies as well.
Now I feel that it would have been better if I had allocated the time and money on exercise.
very interesting thanks for sharing
I always felt the ivermectin claims were dubious at best and I guess this is the first time I have ever seen anything that is remotely scientific suggesting how it might work. There are so many claims and no substantiation for their value when it comes to remedies in Parkinson's.
Thanks for sharing this. Very interesting! I have been on Ivermectrin for 4 months. My Parkinsons came on immediately following the Covid shot.My Dr. believes I have been injured by it and is treating me to remove the spike protein. He calls it long haul covid spike injury. It's really fascinating that it can also help with neurodegenerative disease.
My tremor started the day after my second Covid vaccine, although my Doctor said there is no proof the vaccine causes Parkinson's.
There is a large group of Dr's. around the USA that do believe it can cause injury and are treating it.
What is the treatment?
Ivermectrin is one. The nicotine patch also works. CBG and Nattokinase are also used.
Nattokinase from Natto. That at least sounds natural. Maybe it’s why Japanese traditional diet helps longevity if it cleans up after viruses.
Cannabigerol (CBG), another active compound found in hemp and cannabis sativa plants, is becoming increasingly common, appearing alongside CBD in many products. Like CBD, CBG is derived from hemp, but it doesn't have intoxicatingly psychoactive effects like tetrahydrocannabinol (THC).
You should ask your Neurologist about PEG and what induces macromolecular crowding in trials and then ask them to explain what the effect of endotoxins are on immune pathways. If they can’t answer, find a new doctor. Sadly most Doctors aren’t scientists. They don’t conduct trials for the most part. With re to the mRNA shots and viral pathogenesis, the spike protein is pathogenic in all its forms but more so when wrapped in lipid nano particles that continuously circulate and then add in endotoxins. My two cents.
My husband's first tremor started after his first Covid vaccine, and his symptoms got worse after actually catching Covid. There does seem to be research now on the links between Parkinson's & Covid - www1.racgp.org.au/newsgp/cl... .
Ivermectin is also an anti-fungal, and my husband seems to do better with anti-fungal botanicals and foods treated with antifungal preservatives, especially proprionate, medicalxpress.com/news/2024... .
Thanks .. is proprionate available in a capsule or other?
I have not seen it in capsule form. It is sold as a powder on Amazon to use as a preservative in foods, but we haven't tried that route yet. I just noticed that some of the purchased foods he seems to do better with have preservatives, especially proprionate. Started looking that up and found some studies on it possibly helping PD.
Propionate is also available as a supplement in capsules. I personally take 2 x 500 mg daily. Initially, it was only for my peripheral neuropathy, but various studies do indeed show favorable results for MS as well, and now also for PD!
Good to know. What is the brand name of your capsules?
Propionic Acid (Sodium Propionate) - 200 Capsules (500 mg) - Made in Germany - Vegan - TRUE NATURE®
On Amazon.com, I couldn't find any capsules, but I did buy them on the German Amazon.de. In addition to extensive propionate research, it seems that most propionic acid capsules also come from Germany (Propionsaüre). Therefore, I will provide a few other producers that may ship to the USA:
Solvisan Propionic Acid Capsules with Sodium Propionate 500 mg – 200 Capsules – Pure and Vegan
Supplenatura® Propionic Acid, 210 Capsules (500 mg) High Purity Sodium Propionate, Laboratory Tested, 100% Vegan, Free from Additives - Made in Germany
ZeinPharma Propionic Acid 500 mg 120 Capsules - Sodium Propionate Pure and in Optimal Dosage, Intestinal Flora Capsules, Dietary Supplement Vegan, Laboratory Tested
Removal of the spike protein, would be extremely interested in hearing more about that!
The Nicotine patch works, Ivermectrin and CBG, the supplement Nittokinase taken on an empty stomach helps to aid in the removal. Being under the supervision of a Dr.would be best.
I read that Nattokinase breaks down the spike proteins.
A couple of questions spring to mind. Is the ivermectin treatment alongside your regular meds, and are you taking levodopa based ones? And is the ivermectin affecting the levadopa dosage requirement at all, as the article seems to imply that it might?
I am not taking any lavadopa carbidopa
According to Sabine Hazan MD , invermectin increases the presence of bifidobacteria, this is the difference between those who develop the Covid disease and those who don't. Is there also some correlation with PD?
chartist
Greetings from Italy
Basilico
That is very interesting!I don't know about a correlation with PD but that would ɓe interesting to know.
Beautiful plant!
Have you ever wondered what happens to bifidobacteria as we age? Might that explain age of disease presentation? Leaky gut, leaky BBB. There is absolutely a connection between the biome and the brain, between the biome and health. Why would something like ursodeoxycholic acid be immunomodulatory? The biggest mistake Western medicine did was compartmentalized disease. What some don’t realize is the research being conducted with IVM in the areas of cancer as well as autoimmunity. The mechanisms of action are still, even today years after discovery, being understood and which pathways it acts on. The complete demonization of IVM in Covid was purely driven by profit and pushing through EUA for an untested failed technology platform with inherent issues with scalability and production. And as an end question what decimates bifidobacteria?
Btw Gioc this post:
healthunlocked.com/cure-par...
Is spot on. You know what else is in the manufacturing process of Mrna…LPS. The vaccines are riddled with endotoxins not to mention contaminants. Already cross checked amongst multiple labs world wide. This is separate to the pathogenic spike protein and LNPs
I have the same story as you. Fit as a fiddle, went to gym 6 days a week doing HIT and weights … my husband lost 20kgs…. We were smashing it.. than covid hit and we got the vac…. I slowly started to decay and 9 months later was diagnosed with PD (rigidity, bradykinesia, illegible hand writing, small motor skills gone)… I had no signs or symptoms of PD prior to getting the covid vax…. May you kindly share how your gp is treating you… I am 52 with 3 young kids and completed devastated by this!
I will help you 🙂 I'm 54 with 3 kids, one being special needs. Feel free to private message me.
I understand that devastating feeling. There is always hope.
thank you so much. How do I PM you?
There is a private messaging option on this platform.
Check for ‘Chat/Message’ symbol🌺
Press my icon button and then hit chat
Wow 🥰
But how can you tell whether it was taking the vaccine or being exposed to the virus that caused the issues?
And how can you know that if you hadn’t taken the vaccine and had caught covid (inevitable) you wouldn’t have been even worse or even died. Maybe you had been exposed just before taking the vaccine so were already dosed with spike from the actual virus.
That is the problem here. There is no way of doing a fair trial as there was no group of people to use as a control that were never exposed to the spike. NZ was the closest as most of the population was immunised with Pfizer before the virus managed to get into the country. I would love to see a study comparing nz experience to other countries where people were exposed before the vaccine was available.
The state of Western Australia was as isolated as New Zealand. WA isolated itself from the rest of Australia. During this isolation, WA residents had uninterrupted access to healthcare, allowing for a relatively normal life. Covid vaccination rates were in the 90% range. Then the borders reopened. The reports of vaccine adverse events, surpassing expectations when compared to normal traditional technology vaccination rate reporting. All-cause mortality rates rose significantly, beyond the percentages for Covid-related deaths. The key point is that the increase in deaths started climbing in May 2021 immediately after the vaccine rollout but well before borders opened & Covid broke out.
So there was no cases of covid in Western Australia prior to the vaccines?
From google
The COVID-19 pandemic in Western Australia is part of the ongoing worldwide pandemic caused by severe acute respiratory syndrome coronavirus 2. Western Australia (WA) confirmed its first case of COVID-19 on 21 February 2020, and its first death on 1 March.
So COVID was in the population before the vaccine?
were the excess deaths counting the people from the cruise ship that were all infected?
I think AstraZeneca had more adverse reactions to Pfizer?
Here's a news report from 31st Dec 2020, News Years Day, and celebrating 263 days Covid free days.
They had nine deaths in a population of 2.6M from the start of the Covid in early 2020 until when they opened their borders, post vaccination roll out.
But at that point more people also had caught the virus too? I don’t know how you can separate deaths from the vaccine from deaths from the virus
Western Australia had no cases when the vaccine roll out began in WA in March 2021, first for health works and then onto the older brackets over the next few months . The excess deaths' rise was from May 2021. Borders didn't open until March 2022. Covid cases were negligible until opening up borders.
Seriously, it was comical, the politicians even went on TV to say how under strain the hospitals were. Here is the Western Australian premier Mike McGowan giving a press conference whilst borders were still shut in Nov 2021, and wondering out loud what the hell was going on, why are the hospital emergency departments being over run?
And it wasn't from not being able to see doctors & specialists for diagnosis during 20/21 for other ailments because they did have access. Life was relatively normal. What correlated precisely with the hospitals being over run was the roll out, particularly when the boosters (Pfizer) started October 2021. Which times perfectly with the Premier's press conference appearance in Nov 2021.
I think WA is the perfect case study for assessment of the Covid vaccine safety.
x.com/AusMortality/status/1...
Strange, I don’t think the same happened in nz. Maybe the AstraZeneca and Pfizer didn’t react well with each other. We only had the pfizer
ah, found this
“
Author & abstract
Download & other version
Related works & more
Corrections
Author
Listed:
John Gibson
(University of Waikato)
Registered:
John Gibson
Abstract
Accurate data on health and economic outcomes are needed to evaluate policy responses to COVID-19. A potentially comprehensive health indicator is excess deaths, which shows the gap between all-cause deaths and deaths to be expected under normal circumstances. New Zealand's public health community has seized upon an excess deaths series that seemingly shows negative cumulative excess mortality in the first three years of COVID-19 - in other words, fewer deaths than expected. This is a flawed measure because it ignores changes in population growth. There was a rapid rise in deaths in New Zealand in the 2015-19 period, due to immigration-driven population growth rates of two percent per annum. This growth came almost to a standstill after the border closed in March 2020 so methods of extrapolating from the past to predict future deaths, to ascertain if actual deaths exceed the projection, must take account of this sharp change in population growth rates. Rather than New Zealand being unique, in having negative cumulative excess deaths in the COVID-19 era, as claimed by public health commentators, cumulative deaths are about four percent above expected deaths once population changes are accounted for. Several developed countries had better outcomes according to this indicator.”
But over the covid period there must have been deaths caused by the virus too counted in the excess deaths? Statistics are so easy to fudge.
And tandfonline.com/doi/full/10...
I might wait till tomorrow to read this properly. 😅
I do think though there would have been far more excess deaths if there was no vaccination carried out. That is what we should compare against. And you can’t compare the excess deaths with or without a vaccination programme of course. So to me it seems vaccinating is probably the lesser of 2 evils and the side effects of a bad dose of the virus would probably be worse. It’s not like there was an option of never being exposed to the virus.
is it working ie; the ivermectin…. Are your PD symptoms going?
I'm seeing some progress but as my Dr. layers treatments I feel worse. It's like taking 6 steps backwards 2 steps forward. This week I feel good and see improvement. The changes seem subtle. I'm talking better,less brain fog,I have more energy and stamina.
Did you have the diagnosis confirmed with a DAT scan yet? I did not have the jab but my symptoms accelerated rapidly after Covid arrived, am on low dose Sinemet. I’m doing a host of other things more holistic. Nicotine patches certainly helped me a lot.
Yes, I had low dopamine. I was tested for underlying conditions soon after and I had and was treated for Bartonella and Mono. My current Dr. is convinced I have spike injury. I have nothing to lose and am just waiting to see the evidence and believe I am seeing some. He is a good Dr. and I trust him. It's been a crazy road but I'm just not willing to give up until I find every answer. Stubborn I guess 😆
You are very lucky to have a doctor who is well versed in spikeopathy.
I'm realizing that more and more.
But how does he know it is the spike and not the other conditions that are known to cause symptoms. The fact that he is convinced you have spike injury and isn’t considering other obvious potential causes is a worry I would say. Sounds like he is trying to prove a theory. I would get another opinion.
He has explored other options. I have seen many Dr's and had many tests.I now have all my answers and this is just one piece of the puzzle. There is no guarantee that this is completely true. I have been down every road. This is my personal journey and I have to know and I trust this Dr. Either way I will have an answer and I'll move on.
I got the shot because my husband has CLL chronic lymphocytic leukemia and the Dr.said he couldn't receive treatment unless he got the shot. I got it for him. The crazy thing is...right after we got the 2nd shot our family got covid. He had it the worst.I was the only one out of 5 that did not get it. My husband is doing well now, thank God!
The vaccine doesn’t stop you catching the virus. It just lessens the chance of severe outcomes. I’d say you were lucky to have had the first shot at least.
If you had only just had the second shot you wouldn’t have had enough time for the increased immunity to occur. That takes a few weeks.
Yes, I realize that. I obviously wish I didn't have it. As soon as I got the shot I went into immediate frozen shoulder. It was the worst pain I had ever had. I respect everyone's differences of opinion on the covid shot. We all just made the best decision we could at the time.
Perhaps it was poor administration of the shot injected into the wrong site.
If the reaction was immediate seems unlikely it was caused by the ingredients, more likely it damaged a nerve or something?
All I know is I was healthy and no issues before the shot. It was an immediate impingement then frozen shoulder then the shaking started over the next 4 months. I'm really not trying to prove anything. This is just my story, weather the shot is responsible or not, I don't know.
I feel very good about the team of Dr's I have been working with.
you’re lucky to have good doctors looking after you 🙂
Thanks! It's been a hard road. I know it has been for everyone on here. It makes a big difference finding good Dr's and people pointing you in the right direction.
The Covid vaccines were supposed to be intramuscular and not intravenous. Aspiration is required to ensure intramuscular dispersion of the vaccine which is something I insisted on. I spoke to 3 doctor friends about this and they all said we'd never do that because it's too painful. I never noticed any pain...
I think if you are getting die off from a virus, bacteria or fungi you can feel worse for a while.
Very interesting and thanks for sharing! I would like to hear what effects, if any you notice going forward with this!
One thing my Dr. noticed 3 weeks after taking the Ivermectrin is the cogwheel resistance in my arms disappeared and has not returned. I will be happy to share if I find anything else good comes from it. Change takes time at a cellular level and can be subtle.
Can you share the dosage and frequency of the Ivermectin treatment ✨🙏🏾✨
20 mg. 1 time per day
mmmmm gotta wonder if these claims aren’t due to the vaccine but the after effects of catching the virus or the anxiety caused by the worry about the virus, lockdowns, and just getting older. This part makes me sceptical of the rest of the study.
From the link above:
“A team of top researchers in South Korea analyzed the electronic health records of 4.3 million individuals in Seoul. The study revealed that those who had received mRNA
injections experienced the following:
• 68% rise in depression
• 44% surge in anxiety and related disorders
• 93.4% increase in sleep disorders
• 138% jump in mild cognitive impairment
• 23% rise in Alzheimer's disease”
these could easily just be from the social impact of the covid experience causing anxiety, or from catching the virus
I don't trust that mRNA vaccine for that matter, insisted on Pfizer. Was very disappointed to see that the mRNA won out in the sole source contract of several hundred million dollars given out by the US a week ago.
I don't know about neuro protection certainly it seems to have an agonizing effect upon dopamine release (assuming there is still enough dopamine 2 release or that which is there is allowed to release, in respect of that latest Bernstein thesis) and that's interesting. And it's very interesting about the long-covid injury, whether the source is the mRNA vaccine or the virus, It will have to be tracked down obviously which one it is. Seems to be vaccine version produced by Pfizer is safer than the mRNA vaccine. I don't think LAJ has any basis for making a psychogenic connection from a mega observational study, there is just as much if not more potential for the idea that covid infection is the source, along with being obese or having preexisting heart and diabetes complications, or more than one at the same time, plus potential combined effect of multiple sources of disease since there are significant lifestyle changes associated with infection and a very large proportion of those who died had obesity, cardiovascular, pulmonary, and diabetic problems, some of them were many of them had more than one going on at the time. On top of that many of those symptoms in LAJ's list can occur as simple loss or interference or withdrawal of dopamine from whatever source or cause. Dopamine is your feel good neurotransmitter! LAJ if you wouldn't mind revealing your source of study for your quote... Maybe we can track some of that down. If I could no longer taste Korean food I'd get depressed and anxious and have all sorts of withdrawal symptoms too for that matter.
I was quoting from the link above that the post is on. That is exactly my point. How can they say that those increases were caused by the vaccine and not the actual virus or the social impact of the whole covid experience on society.I think NZ is an ideal place to do a study. It is almost unique in the world for keeping the virus out until almost everyone was vaccinated. It would be interesting to see if the excess deaths some of these antivaccine groups are worried about happened here. In NZ the vaccine was only given to people who had never been exposed to the virus for quite a long time.
pubmed.ncbi.nlm.nih.gov/376...
“'Spikeopathy': COVID-19 Spike Protein Is Pathogenic, from Both Virus and Vaccine mRNA”
“Spike protein pathogenicity, termed 'spikeopathy', whether from the SARS-CoV-2 virus or produced by vaccine gene codes, akin to a 'synthetic virus', is increasingly understood in terms of molecular biology and pathophysiology.”
From both virus and vaccine. So arguably a small amount from a vaccine is preferable to a megadose from catching it?
Mio marito, in Italia, ha ricevuto 3 dosi di vaccino (2 di Pfizer e una di Moderna), poi entrambi abbiamo contratto il Covid in forma lieve, come un'influenza, a settembre 2022. Era diagnosticato PD dal 2017, con sintomi abbastanza ben controllati. Dopo i vaccini, e ancor di più dopo il Covid, ha cominciato ad avere disturbi cognitivi e tanta rigidità. Questa è la nostra esperienza.
Translated “My husband, in Italy, received 3 doses of the vaccine (2 of Pfizer and one of Moderna), then we both contracted Covid in a mild form, like a flu, in September 2022. He had been diagnosed with PD since 2017, with quite well controlled. After the vaccines, and even more so after Covid, he began to have cognitive disorders and a lot of rigidity. This is our experience.”
onlinelibrary.wiley.com/doi...
When you have persistent hyperactivation of STING whether through recombinant spike protein or or wild type spike protein, and the cascade effect….autoimmunity will shift to overdrive. 😪
So it possible to distinguish the spike from the vaccine from the spike from the virus then. Interesting.But you would have test deaths for both spikes. If the vaccine one is present not the natural one you could conclude it could have been caused by the vaccine but if both are present how do you know which is the culprit?
as I have said before, they are both bad. The platform of Mrna is very problematic, particularly LNPs and of course endotoxins that were found. Seneff and many other have outlined why. Listen to her talk or search for the papers. It’s very clear.
But there is no realistic way of protecting from the spike from the actual virus now it is in the community forever. Everyone will be exposed.
So although the spike from the vaccine is also harmful, the likelihood of severe illness and long term effects or death from covid in certain groups like the elderly and people with preexisting conditions is likely much higher, and probably inevitable after several bouts of the infection.
So we are in a no win situation unless someone comes up with a less harmful vaccine that can be quickly modified in time to be effective against changing variants.
Does it mean perhaps younger and fitter people shouldn’t get the vaccine? Well they are going to be exposed to the virus spike anyway and still can’t avoid the spike so I would say having at least 2 doses of the vaccine probably is still best for most.
Unless they can prove the vaccine spike is a magnitude worse than the natural spike? Is there a paper on how they compare?
Definitely if someone can find a way to defuse the spike quickly if it is harmful that would be ideal except it is that spike protein that gives the immunity isn’t it? And get rid of other harmful ingredients
**chatgpt says
“Yes, the spike protein produced by COVID-19 vaccines plays a crucial role in generating immunity. Here's how it works:
mRNA Vaccines (Pfizer-BioNTech and Moderna):
These vaccines contain messenger RNA (mRNA) that encodes the spike protein of the SARS-CoV-2 virus.
After vaccination, the mRNA is taken up by cells in the body, which then use the instructions to produce the spike protein.
The immune system recognizes this spike protein as foreign and mounts an immune response, producing antibodies and activating T-cells.
Viral Vector Vaccines (AstraZeneca and Johnson & Johnson):
These vaccines use a harmless viral vector (like an adenovirus) to deliver the genetic code for the spike protein into cells.
Once inside the cells, the genetic code is used to produce the spike protein, prompting an immune response similar to that of the mRNA vaccines.
Protein Subunit Vaccines (e.g., Novavax):
These vaccines contain harmless pieces of the spike protein (subunits) directly, rather than genetic material.
When the immune system encounters these proteins, it recognizes them as foreign and generates an immune response.
In all cases, the key to immunity is the immune system's ability to recognize the spike protein. When the actual virus is encountered, the immune system can quickly recognize and respond to the spike protein, neutralizing the virus and preventing severe illness.
Thus, the spike protein produced or presented by the vaccine trains the immune system to recognize and combat the virus, providing immunity.”
Which vaccine was the most effective in preventing severe outcomes?
“The effectiveness of COVID-19 vaccines at preventing severe outcomes has varied over time and across different populations. However, the mRNA vaccines (Pfizer-BioNTech's BNT162b2 and Moderna's mRNA-1273) have generally been shown to be highly effective at preventing severe illness, hospitalization, and death. Here are some key points regarding their effectiveness:
Pfizer-BioNTech (BNT162b2):
Clinical trials and real-world data have shown high efficacy in preventing severe outcomes.
Initial clinical trials demonstrated around 95% efficacy in preventing symptomatic COVID-19.
Subsequent studies have confirmed strong protection against severe disease, especially after two doses and with booster shots.
Moderna (mRNA-1273):
Similar to Pfizer-BioNTech, Moderna's vaccine has shown high efficacy in clinical trials and real-world settings.
Initial trials reported about 94.1% efficacy in preventing symptomatic COVID-19.
Strong protection against severe disease has been consistently observed, particularly after two doses and with booster doses.
Johnson & Johnson (Janssen Ad26.COV2.S):
This single-dose vaccine showed lower overall efficacy in preventing symptomatic COVID-19 compared to mRNA vaccines, but still provided robust protection against severe disease.
Clinical trials demonstrated about 66% efficacy in preventing moderate to severe COVID-19, but higher efficacy (85%) against severe outcomes.
AstraZeneca (Vaxzevria, AZD1222):
The AstraZeneca vaccine showed around 70% efficacy in preventing symptomatic COVID-19 in initial trials.
It has been effective at preventing severe disease and hospitalization, particularly after two doses.
Novavax (NVX-CoV2373):
This protein subunit vaccine has shown high efficacy in clinical trials, with around 90% efficacy in preventing symptomatic COVID-19.
It has also been effective at preventing severe outcomes.
The effectiveness of these vaccines can be influenced by factors such as the emergence of new variants, the duration since vaccination, and the presence of booster doses. Booster shots have been particularly important in maintaining high levels of protection against severe outcomes, especially with the emergence of variants like Delta and Omicron.
Overall, the mRNA vaccines (Pfizer-BioNTech and Moderna) have been particularly notable for their high efficacy in preventing severe COVID-19 outcomes.”
This is a good paper to read
frontiersin.org/journals/im...
“mRNA-LNP-associated adverse events – both inflammatory and inhibitory
The SAEs reported with the mRNA-LNP platform are very diverse. The SAEs are likely caused by the combination of the mRNA-LNP vaccine components (103) and potentially by direct toxicity and biological action of the spike protein itself (104–108). Here, we will focus on SAEs likely mediated by the immune system. The SAEs can be divided into inflammatory and anergic/inhibitory categories from an immunological perspective. Inflammatory side effects include acute reactogenicities (fever, headache, fatigue, myalgia and arthralgia, chills, etc.) (45, 46), inflammatory/autoimmune, anti-PEG mediated CARPA (109), and other related events that involve activation of the innate and adaptive immune systems. Anergic side effects, i.e., immune suppression, are presented as virus reactivation where viruses like varicella-zoster virus (VZV) (110, 111) and hepatitis C virus (112) reoccur following COVID-19 mRNA vaccine injection. Furthermore, have also been reported to likely increase the risks in sensitivity to infections (100, 101, 113) and potentially disturbance of cancer immunosurveillance (114–117). How can a platform both activate and suppress immune responses?”
”Inflammatory responses
As discussed above, the inflammatory nature of this therapeutic is linked to the ionizable lipid component of the LNPs (12), which, in effect, might further be accentuated by potential pro-inflammatory contaminants, such as dsRNA (7). The acute reactogenicity responses observed with these therapeutics, such as fever, headache, fatigue, myalgia, arthralgia, chills, etc., are likely triggered by the release of a variety of high amounts of innate inflammatory cytokines, such as IL-1β, IL-6, GM-CSF and type I interferon (7, 12) upon exposure. This inflammatory environment induced by this therapeutic, and that the mRNA-LNP has additive effects with other inflammatory agents, such as LPS (118), could potentially support flareups with pre-existing autoimmune conditions and/or create conditions for novel autoimmune responses to develop in susceptible people. Since the mRNA-LNP diffuses throughout the body (6, 10, 41, 42), and LNPs can deliver mRNA into any cell type and enable its translation, it is reasonable to consider an off-target translation of protein-of-interest in non-APCs, which then could be under attack by the antigen-specific adaptive immune responses (103). Therefore, the destruction of spike protein- or frameshifted-protein-expressing cells by the immune system throughout the body might be responsible for some of the SAEs reported with this platform, such as COVID arm, peri/myocarditis, and inflammatory responses affecting the brain, liver, bone marrow, etc.”
Here is chat gpts summary of that paper “for dummies”
“Absolutely, I can help summarize the key points of the paper under simple headings to make it more digestible:
1. What the Vaccine Does in Your Body
mRNA Basics: The mRNA in the vaccine teaches your cells to make a protein that triggers an immune response. This prepares your body to fight the virus if you're exposed.
Concern About DNA: There’s a debate whether the mRNA can reverse into DNA and integrate into your genome. Normally, our cells don’t do this, but the paper discusses a scenario where this might happen in the lab under specific conditions.
2. How Long Does the Vaccine Stuff Stay in Your Body?
Persistence of mRNA and Protein: The paper discusses findings that vaccine components like mRNA and the spike protein might stay in the body longer than expected. Some studies found traces in lymph nodes weeks after vaccination.
3. Effects on Reproduction and General Health
Reproductive Concerns: There's discussion about the vaccine mRNA possibly reaching reproductive organs, which could be concerning if it affects those cells.
Menstrual Changes: Some women reported changes to their menstrual cycles after vaccination, which is being studied to understand why.
4. Safety and Side Effects
Adverse Reactions: The paper raises concerns about severe reactions and suggests these are more common with mRNA vaccines than others, based on some reports and studies.
Long-Term Uncertainty: It emphasizes that we need more research to understand the long-term safety of these vaccines, especially regarding how they interact with different body systems.
5. Scientific Caution
Need for More Studies: The paper advocates for continuous research to address these questions and concerns, ensuring vaccines are safe and effective for everyone.
This summary simplifies the complex issues discussed in the paper, focusing on the main concerns and findings related to mRNA COVID-19 vaccines. It’s important to continue following updates from reliable health sources and studies for the most current information.”
"...Ivermectin has properties of promoting remyelination in demyelinating diseases like Multiple Sclerosis..." As a veterinarian I used Ivomec daily in large and small animals for 40 years. In some breeds Ivomec caused neurologic symptoms. In all breeds like any other drug the dose is critical. So it does have some sort of effect on the brain. If it can remyelinate the brain that would be a great thing. Too bad they've only reached stage of mice studies.
ok, so where can one even obtain ivermectin these days?
NEW ARTICLE: IVERMECTIN and Multiple Sclerosis - Anti-inflammatory action, neuroprotection and re-myelination!
Breaking NEWS: New 2023 study by Iranian researchers, shows Ivermectin treats Multiple Sclerosis in mice:
2023 Noori et al - Synthesis and evaluation of the effects of solid lipid nanoparticles of ivermectin and ivermectin on cuprizone-induced demyelination via targeting the TRPA1/NF-kB/GFAP signaling pathway
“Ivermectin (IVM) and nano-IVM administration improved behavioral alterations and motor balance in all performed tests demonstrating a reduction in the adverse effects of Cuprizone (CPZ) on myelin”
"To study MS in animal models, the most common method is to trigger the pathology with cuprizone (CPZ). CPZ is a copper chelator whose use induces programmed death in oligodendrocyte cells, chronic inflammation, increased astrocyte and microglial cell activity, and ultimately, myelin destruction"
“Histological analysis (H&E and LFB staining) evidenced that IVM and nano-IVM normalized the morphological alteration induced by CPZ”
“Specifically, the nano-formulation of IVM improved its neuroprotective effects via reducing demyelination or maybe inducing myelin regeneration.”
This adds to the 2018 study by Zabala et al:
“Our results provide evidence that P2X4Rs modulate microglia/macrophage inflammatory responses and identify IVM as a potential candidate among currently used drugs to promote the repair of myelin damage."
"Manipulating innate immune system to promote repair might be a promising therapeutic strategy for treating MS. The results of our study identify P2X4R as a key modulator of microglia/macrophage polarization and support the use of IVM to potentiate a microglia/macrophage switch that favors remyelination in MS.”
“The fact that IVM is already used as an anti‐parasitic agent in humans will facilitate challenging this drug in clinical trials in that demyelinating disease.”
There are more papers supporting the role of Ivermectin in neurological conditions:
Ivermectin promotes peripheral nerve regeneration (2018 Cairns et al)
Ivermectin protects neurons & prolongs lives of ALS mice (Amyotrophic Lateral Sclerosis) (2007 Andries)
Ivermectin has been proposed as a treatment for Parkinson’s Disease (2021, Dongwook Wi, Master’s Thesis)
Ivermectin protects the brain of rats during a stroke, reduces infarct size, improves memory and learning of rats with cerebral ischemia-reperfusion (2023 Seyyedabadi)
Where can I find this actual article, please? I want to send it to my PD sister. She doesn't research her disease (as far as I can tell). She poo-poo-ed taking ivermectin when covid hit and also took 1/2 of the shot. Less than 24 hours after having it she had a huge bloody discharge vaginally (she was 69 at the time). Doctors never gave her an explanation for it. And then a few months later had a stroke that has affected her speech. She was always the picture of health: ate small nutritious meals several times a day; fresh foods; easy on salt & sugar; 107 lbs. My 95 year old Mother lives with her. We have joked that sugar (which is a preservative) has kept her going all these years. She does have a sweet tooth. Hah!
Right here: ncbi.nlm.nih.gov/pmc/articl...
I have a question. When I was diagnosed 10 years ago, I knew that I had some signs and symptoms tracing back many years. I have read that when the doctors do finally diagnose someone that they have over like a 20 year period lost over 50% of their dopamine. This to me does not jive with sudden onset after a vaccine shot? Can this be explained?
Don’t forget that along with getting vaccine everyone was also simultaneously exposed to the actual virus in most countries which obviously also has the spike.
I can’t see how anyone can prove the source of any harm in humans at least. Is there anyone who has never been exposed to the virus?
Yes, I agree. It is always so extremely hard to determine cause and effect. There are so many variables. Also, people may be unaware of what was up next for them shot or no shot. I believe it is human nature to want something easy to blame.
Yes. My fear is next time people will be too scared of the vaccines and the deaths from the next virus will be immense. That is the problem with these types of conversations.
Maybe the vaccine caused some side effect in people. Maybe it unmasked some previously undiagnosed conditions that would have emerged anyway in the near future. But in that case catching the virus and being exposed to multitudes more of the spike protein from the virus would have likely also caused damage., probably worse than the small amount in the vaccine might have caused.
We can’t know. But in NZ most of the population was vaccinated before the virus entered the country and deaths over the covid years were lower than normally expected in a year. That says to me there was at least not much rapid damage caused by the at least the Pfizer jabs..
Subsequently deaths post covid have been higher for a while in older age groups but that is most likely because lockdowns stopped other respiratory viruses spreading during lockdowns so people actually had a few more years than they would have had if it flu etc were spreading as normal. So they were catch up deaths.
I think the nz experience is as close as you can get to a fair trial for the vaccines. At least Pfizer.
There were a couple of younger people who probably died earlier due to myocardial infarction which have been put down to the vaccines. Maybe if they didn’t have the vaccine they would have also died from the virus. Who knows. There were also more suicides and social harm with businesses failing, kids from lower socioeconomic families missing schooling because of lock downs.
The government is now doing a thorough post covid investigation into all aspects of it so that will be interesting.
I agree. Some parents these days do not vaccinate their children and the incidence of these childhood diseases are skyrocketing. The diseases that had been virtually eradicated are back. I hope people come to their senses and stop jumping to conclusions without looking at the complex picture. There is not usually a perfect solution but we work with proper analysis and statistics to get the “best” results which could be equivalent to the least amount of deaths.
The problem is never conversation. Appropriate studies need to be done by various non-biased parties and the public informed. We deserve to know the truth about the virus and the numerous treatments be they traditional, alternative or off-label. We the people need to demand the funding for these studies. We need less bomb production and more health science from our leaders.
Can this be explained?
No. You are correct. Anything could be the straw that breaks the camel's back (i.e the final piece of destruction that results in overt identifiable symptoms) but if you have parkinson's disease (rather than a temporary parkinsonism and the difference is the significant irreversible cell death) then it wasn't solely caused by:
- the shot you had in the months leading up to it
- the stress, trauma or other emotions in the months leading up to it
- anything else that occurred in the months leading up to it.
Ivermectin might be pretty hard to get a hold of in any pharmacy.
Proteolytic enzymes - serratopeptidase and nattokinase bind to proteins
Medical definition: Proteolytic enzymes (proteases) are enzymes that break down protein. These enzymes are made by animals, plants, fungi, and bacteria. Proteolytic enzymes break down proteins in the body or on the skin. This might help with digestion or with the breakdown of proteins involved in swelling and pain.
These need to be taken on an empty stomach and should not be taken with blood thinners.
There are so many threads on Twitter about vaccine injury detox guides, the common denominator I see is ivermectin, natottokinase, NAC.
This medical group in US has taken alot of flack about their alternative treaments for long covid and vaccine injury but they have 100s of positive outcomes.
I am not promoting this but in many, many different groups on twitter discussing vaccine injury have pointed to this group of physicans and their protocol. Just do your own research.
I followed their protocol when I had covid 2x and recovered well. (protocol is different than vaccine injury or long covid)
I’ll just add this “Bifidobacterium reduced the abundance of DSV.”
ncbi.nlm.nih.gov/pmc/articl...
Again what increases bifidobacteria, Ivermectin.
Desulfovibrio app. is GRAM NEGATIVE. Ivermectin is a macrocyclic lactone 22,23-dihydroavermectin B obtained from a GRAM POSITIVE bacterium named Streptomyces avermitilis.
Scroll down to the section: 2.2.2. Neurodegenerative Diseases.
What is of particular interest to me is this:
“Hydrogen sulfide is not the only DSV by-product with effects in PD. Bacterial endotoxin lipopolysaccharide (LPS) may also influence PD outcomes. In an animal model of rotenone-induced PD, DSV overgrowth occurred in PD mice, but fecal microbial transfer (FMT) from healthy mice reversed this phenomenon. Suppression of DSV overgrowth occurred when LPS-triggered Toll-like receptor 4 (TLR4) inflammatory pathway was inhibited [72].“
And as an aside regarding DSV which is a sulfate-reducing bacteria (SRB)
The Desulfovibrio genus includes sulfate metabolizing bacteria that reduce sulfites and sulfates obtained from the diet and sulfated mucopolysaccharides found in mucin leading to the generation of hydrogen sulfide, a cytotoxic compound. Hydrogen sulfide inhibits cytochrome c oxidase in mitochondria, leading to low ATP production. H2S also disrupts calcium homeostasis, leading to high intracellular calcium. Depletion of reduced glutathione leads to generation of reactive oxygen species (ROS).
The entire biome is about balance. DSV in excess is not beneficial to health.
With regards to some of the discussion on this thread and the mRNA SARS COV2 products. I am linking to this recent paper for those interested.
bpspubs.onlinelibrary.wiley...
Long-lasting, biochemically modified mRNA, and its frameshifted recombinant spike proteins in human tissues and circulation after COVID-19 vaccination
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