Diffuse Large B Cell Lymphoma

[Bajabarb]

After 3 prior therapies (Acalabrutinib, Venetoclax and Pirtobrutinib/Obinutuzumab), my CLL/ Marginal Zone Lymphoma has transformed to DLBCL. Has anyone on here been treated with Car-T for DLBCL? Thank you.

[lankisterguy Volunteer]

Hi Bajabarb

I'm so sorry to hear about the transformation. You may find some useful information in the box on this page labeled "Related Posts

*Transformation to Diffuse Large B-Cell Lymphoma

*Relative dose intensity of R‐CHOP independent factor determining favorable overall survival in diffuse large B‐cell lymphoma patients

*Dr Sharman explains how treatment options for the two main subtypes of the aggressive Diffuse Large B Cell Lymphoma are changing

*Richter’s Transformation to Large B-cell Lymphoma

*Landmark' Study Revises Molecular Classification of Most Common Lymphoma

 Cllcanada was a much valued volunteer here & a CLL Hero, he survived a long time after treatment for DLBCL.

>

Or from these 182 previous postings on DLBCL : healthunlocked.com/cllsuppo...

Len

[Bajabarb in reply to lankisterguy]

Thank you so much, Len, not only for your concern but for the extensive list of articles about Car-T and DLBCL. Because timing is so important in this treatment, Car-T is the path forward I have chosen at the advice of my doctors, including Dr. Weirda at MDA. I am just hoping to hear of some positive outcomes from people in similar situations, as this is a very stressful time and I need to think positively as much as I can.

[ncosto]

You may want to watch this video by Dr. Steven Rosen of City of Hope in CA vjhemonc.com/video/8rhz6buh...

[Bajabarb in reply to ncosto]

Thank you, ncosto, for the video of Dr. Rosen. I am aware of the downsides of Car-T treatment but there don’t seem to be many other options at this point. I just have to pray for a miracle cure or to survive long enough for some new, more successful treatment to come along in the meantime. I appreciate your taking the time to respond.

[miskin86]

You can find more people with DLBCL here:reddit.com/r/lymphoma/

[Bajabarb in reply to miskin86]

Thanks a bunch, Miskin! That site, of which I was unaware, seems to have lots of helpful information about DLBCL treatments and afterwards. I am glad you sent it.

[Stewie_1968]

Hi I know there is a Facebook community with this if you look at some of the posts by Priss69 one of our members she talked about it a lot , I think you will find it interesting Let us know if you find the posts etc

Stewie

[Bajabarb in reply to Stewie_1968]

Thank you, Stewie. I will look for it.

[Newdawn Administrator in reply to Bajabarb]

healthunlocked.com/user/Pri...

Newdawn

[Stewie_1968 in reply to Newdawn]

Perfect Newdawn, hopefully might help

[Bajabarb in reply to Newdawn]

Thanks so much, Newdawn! Everything helps!

[Stewie_1968]

But have a look at previous posts by Priss69, one of the others on the site can tell how to do this