Nattokinase

[Zabb]

Does anyone take natto or vitamin k, and does it help with side fx of acalabrutinib? Thanks.

[lankisterguy Volunteer]

Hi Zabb,

I was a little familiar with Vitamin K, since my wife has Factor V Leiden (FVL) blood clotting disorder and among other things she must avoid anything that has Vitamin K like spinach.

When I searched online, Vitamin K promotes blood clotting and Nattokinase seems to inhibit clotting. So I would wonder why someone would take them for side effects of a BTK? Natto would seem to be contra indicated - like other blood thinners for those of us on BTKs. But whether taking Vitamin K is wise should be discussed with your CLL expert.

Len

[mdsp7]

Sometimes I eat Natto, which can be found in the refrigerator section of Japanese grocery stores and which is supposed to be full of microorganisms that are good for your gut, where a lot of our immune cells congregate. Not everyone likes the taste or the slimy texture, but I like it and I feel good when I eat it. I do not know about whether it is good for people taking acalabrutinib.

[SofiaDeo]

I eat it because it's a healthy food, one of the ones that the longest lived people on the planet eat regularly. Hard to say if it would help against any specific acala side effect. I mixa tablespoonful or so into chili beans. I make a dish of chili beans, chopped celery, an ounce of cheese and natto, plus or minus other tidbits like avocado chunks, black olives, bits of chicken or meat.

ncbi.nlm.nih.gov/pmc/articl...

[LeoPa in reply to SofiaDeo]

My grandmother lived to be 96 and she never heard of natto. But she loved bacon 😁. That's how different we all are.

[J1015 in reply to LeoPa]

My grandparents too! Plus whole milk and butter.

[Big_Dee in reply to LeoPa]

Hello LeoPa

My grandmother lived to be 103 and her husband had heart attack at 42. My grandmother was a fabulous cook, really liked her French fries, blueberry pie and spaghetti. She may have made it to 103 because she never remarried after husband died. 😄

[SofiaDeo in reply to LeoPa]

Yes, I am sure her body/gut biota hadn't been affected by the chemicals I and others have too. PBB's in particular, not to mention other toxins in the environment. Plus the effect the targeted treatments have done on my gut.

sph.umich.edu/news/2023post...

[LeoPa in reply to SofiaDeo]

That's for sure.

[GoneWalky in reply to SofiaDeo]

Where do you find good Natto to buy in the US?

[SofiaDeo in reply to GoneWalky]

I get it on Amazon from a company in New Hampshire. There are companies on both the East and West coasts of the US, I believe, that make & sell it. The Rocky Mountains have few food production places, so I have to get it shipped in frozen for this particular brand. I take one container out at a time, thawing it out in the fridge overnight. I go through about 1 container a week, the weeks I open one, I eat maybe a tablespoonful at a time mixed in something. So I average 3-4 times a week over the months, but in reality it's more "eat a container until it's gone, wait a bit, thaw & start on another".

There are supposedly some differences between the small bean & large bean, I just get the small bean.

amazon.com/dp/B075LQ4Z3Z?re...

This brands' containers have a lid, some don't. I wanted one with a lid.

If you have a good Japanese or Asian specialty market near you, they may sell it. A number of Sprouts Farmers Market stores carries it, it's an Instacart item.

[LeoPa]

I take vitamin K2 everyday. The mk7 variety. 120 micrograms per day if I remember correctly. Taking just K is not enough. The conversion into K2 in the body is very inefficient. No idea about the second part of your question regarding Acala.

[BluMts]

I take 100 mcg of vitamin K-2 daily, the MK-7 not MK-4 type. Label says its from chickpea, but used to say from natto. There are scientific papers saying it aids in calcium being absorbed into bones and not being deposited in arteries.

Not heard of any connection with any cancer treatment. Let us know where you saw your info on its link with Acalabrutinib

[Bobby9toes in reply to BluMts]

Same here for the same reason. Never heard of the other. I’ve been taking it for years.