Acid reflux remedy

[tlcladygiraffe]

Does anyone on imbruvica take an acid inhibitor and which one does not interact with imbruvica...reply please asap....need to know.

[june65]

Hi. I have just started Lansaprzol for acid reflux, it seems to be working.

[Jm954 Administrator in reply to june65]

Worked for me too, over the counter treatments not effective. Reflux only lasted about 2 months 😊

[zaax]

Mmm I get acid reflux sometimes. I find that Andrews liver salts help, also I think it might be down to cheese

[grndmthr1 in reply to zaax]

Chewable antacids, recommended by the doctor, seem to work for my husband. He also takes probiotics for bowels and drinks diet tonic water for leg cramps, also recommended by doctor. He had severe cramping and this seems to have really helped. Now, if we could just get fingernail splitting under control. Doing Biotin for that.

[Havemercy]

I have been prescribed a drug called Omeprazole as a preventative against stomach acidity. I also take Ibrutinib (as it is called in UK). No problems.

[jaysearch in reply to Havemercy]

Hi: I was on Omeprazole for a few months, until I learned that it has a negative effect on Calcium. I stopped it and switched to Ranitidine, and it works well. It's also available OTC.

It is sold under a few diffeerent names. Read all labels whenever shopping. Tums works, but can cause additional acid as it wears off.

[francc in reply to jaysearch]

I hope that since this reply, you are aware of problems with ranitidine: drugwatch.com/zantac/recall/

[BeckyLUSA]

I take Lansoprasole. This, I believe, is the generic name in the US. It is one of the older drugs for acid reflux. I tried all the other newer drugs first, but they all exacerbated the lower GI issues I was having with Ibrutinib. This drug, I can tolerate and my CLL specialist approved it for me to use. It has generally worked well for me. Every once in a while I might have bout, but will take a couple of tums and they do the trick. Good luck.

BeckyL USA

[Purple_lady9999]

I was taking protonix before starting ibrutinib, and it's still working great.

[TimHB]

Yes. I got severe acid damage in my esophagus which my docs attributed to either my enlarged spleen or ibrutinib or both. They put me on 40mg of Prilosec daily.

[tlcladygiraffe in reply to TimHB]

How long had you had it..the acid reflux?

[TimHB in reply to tlcladygiraffe]

Hard to say as it came on gradually, but I started to notice it within 6-8 weeks after starting treatment. Prior to treatment, my throat was sore but we thought it was from swollen lymph nodes in my neck, but it's possible that was an early indication of the acid damage from my spleen. The difference now is my entire esophagus is on fire all the time.

[GlobalScouttoo in reply to TimHB]

Omeprazole is the generic of Prilosec and often a lot less expensive

[Jonquiljo]

I have read, though I’d have to find the reference again, that PPI’s (omeprazole, lansoprazole, etc), will change the pharmacokinetics of Ibrutinib - but the actual Ibrutinib dose received will be almost the same as without the PPI’s.

It all has to do with the fact that Ibrutinib is soluble at about pH 3.0. Raising the pH (by PPI’s) will slow the time for the drug to get into your system. Supposedly it’s not a problem because your body will eventually assimilate the Ibrutinib. I think it was Janssen or a Janssen sponsored study (or one of those companies as I forget who owns who).

A good med for a sore and/or damaged esophagus is “sucralfate” (carafate, etc.). Its a suspension that will line your GI tract (especially esophagus) and prevent more acid damage and allow it to heal. Its kind of like swallowing a “chalky” suspension. It will HELP, but you probably need to get your acid under control. Your esophagus has to heal and stay safe. Trust me, I’ve had esopageal problems (all on their own), and acid suppression is the only way to prevent it. What you describe sounds far more severe than “heartburn.”

Either way, as long as you don't let it go on a long time, your esophagus will recover. Personally I would see a GI specialist as most MD’s seem to know very little abour your esophagus and acid problems. I’m sorry this is so difficult - as esophageal problems are very uncomfortable. Good luck.

[terryI_uk]

I was taken off ibrutinib in March because it had exacerbated my acid reflux problem, I had been taking omeprazole for 20+ years for this, ibrutinib for 30 months. An endoscopy revealed severe oesophagitis, gastritis and three duodenal ulcers which had been bleeding. I was prescribed high dose, (80mg), esomeprazole which cleared these issues within 3 months but my haematologist stopped ibrutinib because of risk of severe bleeding. I am on the Flair trial and am currently taking no medication for cll and on last visit to haematology clinic was told I am in complete haematologist remission so some good news at the end. God bless, Terry

[tlcladygiraffe]

Thanks for your replies..we are all dealing with so many health issues because of the meds we take to stay alive....hard to deal with at times.

[Penkman]

I have been on Omeprazole for many years and have been on Ibrutinib now for two months with no adverse affects.

[Berrytog]

Omeprazole 40 mg per day seems to do the trick topped up with Gaviscon if needed but rarely is that necessary. Correct diet is more important, keep away from rich and fried food.

[tlcladygiraffe]

Agree,,,acidic foods and spicy foods ...also have an ulcer

[francc]

I've been on Ibrutinib for 5+ years. I take the generic ranitidine or famotidine from Costco. Much much less expensive and they work quickly. I have always avoided junk food, breads and greasy food... but if I do engage in eating them when traveling, I will have acid reflux for sure. Good luck with finding your solution.

[Zeit]

Hello, I am in a medical trial with Ibrutinib, Pantoprazole a acid reducer was approved by UCSD to be OK to take with Ibrutinib. It works well and is not expensive.

Nancye

[tomhenry2487]

Hi,

As a CLL patient who is also a pharmacist, I prefer to see patients use either ranitidine (Zantac) or famotidine (Pepcid). These are both available over the counter in the US and are realtively inexpensive with generics available. These drugs reduce acid production without completely shutting this process down. There are negative outcomes associated with long term use of the Proton Pump Inhibitors (PPI) such as Pantoprazole and Omeprazole. In addition the Zantac and Pepcid work faster and are more appropriate for use on an "as needed" basis. The PPIs may take a full day or more for you to notice a positive effect and are more intended for short-term daily use.

[Hoffy]

Rising you Bed ( head side) up about 10 mm ( 1/2 inch will help).

Be well,

Hoffy

[W00dfin]

We use a powdered product Tri-Salts from Ecological Formulas. It has 3 ingredients: calcium, magnesium and potassium. The dosage is 1/2 teaspoon mixed in water. It relieves my acid reflux in about a minute.

[tlcladygiraffe in reply to W00dfin]

Great...good to know.

[tlcladygiraffe in reply to W00dfin]

Where do you purchase it?

[W00dfin in reply to tlcladygiraffe]

We buy it online from amazon or whoever has the best price

[tlcladygiraffe in reply to W00dfin]

Thanks...I wonder if it is sold at a health food store.

[Cllcanada Top Poster CURE Hero]

If you have gastroesophageal reflux disease (GERD) you might want to be tested for H pylori infection.

In CLL H.pylori has been associated with ITP, Dr. Zent, of the Mayo Clinic did a number of studies 10 years ago...

Here is the link

clltopics.org/Complications...

~chris

[tlcladygiraffe in reply to Cllcanada]

I have been tested...have an ulcer.