Forward momentum in Richters/DLBCL?

[Smakwater]

A small bit of encouragement.

VJHEMONC video - Graham Collins, MA, MBBS, MRCP, FRCPath, DPhil, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, discusses data from the Phase III POLARIX study (NCT03274492) which evaluated polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone

vjhemonc.com/video/jnnfvh7f...

youtu.be/JNNfvH7FxHc(Not working as expected?)

[AussieNeil Administrator]

Thanks JM, and thanks for assigning a topic. I've actually changed the topic to Richters, which was added to the topics list a while ago.

Priss69 , this will be of interest to you.

Neil

[Smakwater in reply to AussieNeil]

Thanks Neil

[Priss69 in reply to AussieNeil]

Thank you very much for keeping me informed. I have to update all my information about the Richter Transformation

[Deserthope]

My husband was just diagnosed with NHL Richters. It's in his bone marrow. He just had first RCHOP treatment about 3 days ago. We are devastated and scared. He does have 17p deletion. His sister is a bone marrow match. Any hope?

[AussieNeil Administrator in reply to Deserthope]

We do have members who have had their Richters Transformation cured. A stem cell transplant can also cure CLL.

Neil

[Deserthope in reply to AussieNeil]

Thank you. This is some hope. We will take any. He's a strong guy but this is grim news.

[Smakwater in reply to Deserthope]

Of course there is hope. Although Richters is often more aggressive than CLL, It can be cured. There are some on this forum who have overcome Richters.

RCHOP is still the standard therapy, however, there are other avenues in the event that you need another option including CAR-T.

youtube.com/watch?v=YUw2rFS...(Not working as expected?)

cllsociety.org/2021/04/ash-...

Wishing You the best and speedy recovery.

JM

[Deserthope]

Thank you very much. I am trying to be strong, it's so new and there's a lot to take in. We have 3 sons - all 3 will be in college this fall. 3rd son just graduated h.s. 25th wedding anniversary next March.

[Smakwater in reply to Deserthope]

Cancer does not play fair. Through this forum we help each other in part by sharing resources and substantiating hope. I am encouraged that you have three sons to build strength with. I have three brothers, and it has been a great support to have them share in challenge I have brought by having CLL.