Zanubrutinib vs. Ibrutinib Patient Power Video by Dr. Jennifer Brown MD PHD

[lankisterguy]

In this Patient Power video - Dr. Brown is very clear about the advantages of Zanubrutinib over Ibrutinib - especially for 17p and patients with heart risks.

patientpower.info/chronic-l...?

Watch as Jennifer Brown, MD, PhD, Director, CLL Center, Dana Farber, updates our chronic lymphocytic leukemia (CLL) patients on the latest from the 2022 American Society of Hematology (ASH) Annual Meeting, including the results of the ALPINE study and the new BTK inhibitors.

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Len

[Chemtrails-USA]

”….will be our new standard of care BTK inhibitor.”

Was the good doctor referring only to high risk, previously treated CLL patients?

- Bobby

[lankisterguy Administrator Volunteer in reply to Chemtrails-USA]

Hi Chemtrails-USA,

I believe she is indicating that the early / young data shows the strongest benefit to those high risk patients. It will take more time to see if the future data and other studies show a strong or moderate benefit to untreated or other genetic profiles.

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The latest NCCN guidelines recommend Zanubrutinib for all CLL patients - see:

ajmc.com/view/nccn-updates-...

Even though the USA FDA has not approved Zanu for any CLL applications yet.

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The EU & UK may get there first- see: healthunlocked.com/cllsuppo...

healthunlocked.com/cllsuppo...

Len

[Rico49 in reply to lankisterguy]

Good morning. Any insight into what's the hold up at FDA in US? Secondly, is it reasonable to assume Zanubrutinib would penetrate the blood brain barrier like acali and ibrutinib? Thank you

[lankisterguy Administrator Volunteer in reply to Rico49]

Wow those questions are way above my pay grade, you may want to ask your CLL expert doctor for those

[Rico49 in reply to lankisterguy]

Thanks- I just found where it may be approved in Jan 2023??

[Thundercat2]

I needed this today thanks for sharing Len! I think you meant 2022 in your post however not 2002

[lankisterguy Administrator Volunteer in reply to Thundercat2]

Thanks for catching that one- Patient Power gets credit for that typo- LOL

[Denisguay]

2002--?

[lankisterguy Administrator Volunteer in reply to Denisguay]

Thanks for catching that one- Patient Power gets credit for that typo- LOL

[Catnap7]

Thank you very much! 🐈🐈

[bennevisplace]

Len, does one have to register for this content? None of the videos work for me.

[lankisterguy Administrator Volunteer in reply to bennevisplace]

Yes, you need to register- giving your email address to see the videos

[bennevisplace in reply to lankisterguy]

Thanks!