Doubling of absolute Lymphoctes

[WilliamTan]

It has been 11 months now since I was diagnosed with CLL. Thereafter I have been tracking my WBC and Lymphocytes . The trend curve over a year is in the attached picture. I was also taking green tea extract , curcumin , vitamin C and D since being diagnosed. Until now did not experience any B symptoms. Any comments on the trend ? Just wonder if there is more updated information green tea and curcumin for treatment of CLL?

Discussed with my Doctor on 6th July , he recommends a FISH test on my blood. At this moment pending results on the FISH test.

[AussieNeil Administrator]

Hi William,

Your CLL is pretty stable, climbing an average of 13% in 11 months, which works out at a doubling time of about 5 years. Further, doubling time really only becomes important when the lymphocyte count exceeds 30, or at your present rate, in around 8 years. So I reckon you can relax.

With respect to green tea and curcumin, the only clinical trial of curcumin on CLL patients had disappointing results, per my post here: healthunlocked.com/cllsuppo...

There have been no further studies of EGCG extracted from green tea since the company that provided the pharmaceutical grade product stopped supplying it about 10 years ago. See: en.m.wikipedia.org/wiki/Pol...

Neil

[WilliamTan in reply to AussieNeil]

Thanks for always replying promptly and reassuring.

[Bikram21 in reply to AussieNeil]

Hi Neil,Are these percentages used as an actual predictor of when treatment may be needed?

Thanks,

Jeanmarie

[AussieNeil Administrator in reply to Bikram21]

Hi Jeanmarie,

This post covers the triggers for starting treatment:

healthunlocked.com/cllsuppo...

Lymphocyte doubling time under 6 months, particularly when the lymphocyte count is over 30, is an indicator to begin looking for confirmation of other indicators that treatment is needed.

Neil

[Ashwas in reply to AussieNeil]

My WBC started at 24000 in 2003It became 50000 in 2011. Since a lymphoma developed under eye lid, I was treated with rituximab and chemo. Then WBC also became normal till 2016. It started increasing again to 30000 and Again treated with xray and chemo since I developed carcenoma in rectum.

After that WBC became normal . Now WBC again raising fast to 50000. Platlets also reduced to 1 lakh.

Waiting now

[thb4747]

Hi William, just to reinforce Neil’s comments — these numbers show you are a long way off treatment so long as this trend continues. Try not to worry too much and enjoy your life.

[WilliamTan in reply to thb4747]

Nice to hear your response.

[LeoPa]

I've read on this site that supplementation with high dose synthetic vitamin C is not recommended for CLL patients. It's better to get vitamin C from natural sources. Red bell pepper is ideal.

[WilliamTan in reply to LeoPa]

I have noted your reply. Thanks for your feedback.

[Big_Dee]

Hello WilliamTan

Not to worry, my ALC (Absolute Lymphocyte Count) was doubling every 2.5 months and I am still here almost 4 years later. Blessings.