Sirturo, targeted the fuel supply of cancer cells and blocked metastasis by nearly 85%. The drug had no effects on normal cells, thereby minimizing side-effects. It found that treatment with Sirturo caused a 'power failure," but only in cancer cells.
Sirturo is already FDA-approved, with these findings paving the way for new cancer clinical trials.
More here: medicalxpress.com/news/2021...
Interesting, thanks.
Link to the paper in Nature nature.com/articles/s41418-...
The idea of ATP depletion in cancer treatment goes back at least 20 years. I don't know of any clinical trials.
Targeting cell death: helping push cancer cells over the edge
Newly-discovered human organ may help explain how cancer spreads
Omega-3s could boost immunotherapy's cancer-fighting power
losing white cells when on no cancer treatment
What High and Low Immunoglobulin G Levels Mean for People With Cancer - A Review from the Patient Power Information Resource
