Trigger finger & costochondritis from Acalabrutinib?

[Seok]

Hi Everyone

My trigger finger recurred after cortisone jab in February. Recently developed symptoms similar to costochondritis (painful sternum and tight chest muscles) after vaccination and lasted over 2 months.

Called Pharmacist in Biologics and he hadn’t come across such incidents. Wonder if anyone here also experienced such side effects from acalabrutinib?

Seok

[AussieNeil Partner Administrator]

I had two ER visits in a week due to severe chest pain to the lower left of my sternum with symptoms similar to costochondritis within a couple of months of starting Acalabrutinib. I needed very strong pain meds just to be able to walk. Heart checked out fine. Pain gradually waned over the next month.

Neil

[jonathan7176]

I’ve been suffering with this on and off since I fell ill with a bad chest infection in March, which led to my diagnosis in hospital. Dr prescribed me Vitamin D a couple of weeks back and suggested my deficiency might be responsible. It did settle, though not completely.

I restarted Acalabrutinib 10 days ago after a fever spike and it has flared up again in the past few days, especially painful today. I’m breathing OK but feel constricted. I hope it is a temporary side effect and nothing to do with my lungs!

Good to find this post!

[Justasheet1 in reply to jonathan7176]

Jon,

Have you had a chest xray?

Jeff

[jonathan7176 in reply to Justasheet1]

A couple – though not specifically for this. Didn’t show anything.

[Seok in reply to jonathan7176]

Oh dear Jonathan, I hope you get over with this soon.

The “chest tightness” resolved by itself before I had heart MRI and cardiology consultation. Hopefully it was transient side effect from acalabrutinib.