What is a non chemotherapy treatment regimen to treat CLl

[Joffre1]

I have just had my regular 6 week visit to my oncologist/haematologist .My readings have jumped after being stable since last November.

ALC 84. Has been at 69 since last April. Dx 2016 Alc 21 has gradually increased .

However my eGFR has dropped to 44 reference no is > 59. Creatinine is 139.above the reference no. Of 60 -115

Has anyone experienced a similar drop. Doc. Is suggesting kidney biopsy next week.Before deciding on treatments. Has always said FCR but has now changed to BR ? I am 73 and pretty fit. No other major symptoms except fatigue.

Regards

Joffre1

[AussieNeil Partner Administrator]

I take it you live in the UK? What non-chemo treatments are available depends on where you life, your past treatment history and your access to clinical trials.

The two major categories of non-chemo treatments available outside of clinical trials are CD20 monoclonal antibodies like Rituximab and Gazyva and inhibitor/small molecule treatments like Ibrutinib, Idelalisib and Venetoclax.

Neil

[Joffre1]

Hi Aussieneil

No I am in Aus. QLD.

[AussieNeil Partner Administrator in reply to Joffre1]

Unfortunately access to non chemo treatments in Australia for your first treatment is limited to those with 17p/TP53 deletions.

[Joffre1 in reply to AussieNeil]

Thnks Neill.

[Joffre1]

Hi MsLockYourPosts

Thanks for the rapid response.

I presume he will do those tests next week my GP alerted me to my high Creatinine levels last year around 110-120 levels and my eGFR levels around mid 50's. My bloods are monitored each 4-6 weeks.

So the drop to 44 was a surprise.I did note a reading of 46 in 2017.

Kind regards

Joffre 1. In Aus.

[MsLockYourPosts Passed Volunteer]

It’s good that you are being monitored, but remember that counts can bounce sometimes for no reason or because of lab error. Look for your overall patterns. It sounds like your doctors are doing that.

[Joffre1]

Thanks Mslockyour post

Will do that🤔😁

[MsLockYourPosts Passed Volunteer]

I don’t know whether you have missed my two PMS requesting that you lock the original post in this thread for the sake of my privacy. I included more information than I want public, as I felt that the information would be helpful to you, given that you didn’t have much time before your biopsy. If you want the post to remain public, I will simply delete my answer.