UPDATE: hi everyone.... Just wanted to post an update on my brother and say thank you to everyone for all the info.... Really helped us have intelligent and productive conversations with our new doctor at Yale today.
We saw the new doc. He was amazing. We spent 2+hrs explaining everything anyone ever wanted to know about CLL. He answered all our questions and I feel my brother now has the information and confidence in his doctor to proceed with treatment. The doctor is reccomending FCR (I believe) chemo. He will have 6 rounds. He ordered a bunch of tests like the FISH and some others ( I forget the names) but he is giving my brother a month to think it over and return back hopefully ready to start treatment which he is reccomending right now bc of his age, and the magnitude of lymph node swelling he has in neck, axilla, and groin. Interestingly, and looking for any feedback from you guys on this. I started doing some digging into our fathers side of the family. We dont know him and have never had a relationship...so I didnt know the family history from that side but felt like I needed to. Anyway, our father (mine and my brothers) apparently has CLL, and his sister (our aunt) also has CLL... But no other members have it. I dont have more details then that right now but I plan to find out more like age of diagnoses (although I believe was 50/60yrs), chromosomal abnormalities etc as soon as I can. I couldnt find a ton on inheritence of CLL just that 10% of people with CLL have some blood cancer in their family. Thought it was odd that both him and his sister have it, and now my brother (at 31yrs old-young for this diagnosis) has it. Unfortunately, I tracked down this info after our apt with his great new doctor today but I will obviously bring this up at the next meeting. Any one with any studies/info/personal history anything on inheritence would be so so appreciated. Again thanks to everyone for all the help thus far!!!