I am a 78 year old male living in the UK. Started treatment 3 years ago. Had two rounds of FCR which was stopped due to my bone marrow being wrecked. Managed to get on to Ibrutinib as a named patient via Dr Anna Schuh in Oxford. Now under the care of my local haematology consultant in Hereford. After 21 months on Ibrutinib which quite quickly got my blood results back in normal range, my kidney function started to deteriorate and my consultant stopped the Ibrutinib. My bloods continued to be in normal range for 8 or 9 months without any treatment and I have felt well.
However, my last 3 monthly blood tests have shown my white blood count and lymphocytes rising - now 23.7k and 17.9 respectively. I believe I am heading for treatment again. My question is, what drug would be appropriate bearing in mind, my poor kidney function ? Venetoclax ?