I ama 70 year old male living in South Africa and was diagnosed with CLL in January 2013. I had no symptoms that I was aware of and after a particularly nasty fever was sent by my GP for a blood count which revealed the CLL . I was referred to an Oncologist and sent for a Catscan and Bone marrow biopsy which revealed a marrow infiltration of over 80%. The Oncologist decided to commence treatment right away which consisted initially of Rchop for the initial infusions and then FCR which were completed in October of that year. Bone marrow biopsys revealed a complete remission and I continued to lead an active life . In November 2015 a biopsy of the marrow revealed 40% infiltration of the marrow and my Oncologist in consultation with a Haemotologist decided to delay further treatment as my blood were pretty stable. I have now had a further marrow biopsy which has revealed an 80% marrow infiltration. Strangely my blood remains fairly stable at Red Cell 3.76 Haemoglobin 13.3 white cell 6.6 Neutrophils 1.22 Lymphocytes 5,28 and platelets which have always been low at 70.
Where do we go from here. I am told Ibrutinib is exorbitantly expensive and as far as I can gather no trials exist in South Africa. Is further FCR an option or will it damage the bone marrow irreparably? Other than a cold and a chest infection this winter I have no real symptoms. I am fit playing golf 3 times a week and walking the 18 holes. What are my options. Is a trip to the UK to get onto one of the trials an option??