I have been fighting the weary to the bone fatigue for months now. I got so tired of being just a lump laying in the house. I'd just go to the store and come home and take a three hour nap. I conveyed this Monday to my family doctor. I told him that I was ready to through in the towel. He told me that he is starting to believe the fatigue is truly due to the CLL. He started to leave the room then he stopped and came back. He told me he wanted to try something but is would be kind of a long shot. He gave me a few samples of Nuvigil. It is meant for people that has narcolepsy and people that work shift and have trouble staying fully awake. I took my first one before work this morning. I could feel it, gently, on my way to work. I felt energized and no brain fog all day. I came home and actually mowed my front yard. My breathing seemed much better. I can climb stairs without getting winded. Now granted this was my first day. I'm really hoping it doesn't cause any sleep or greater fatigue when I wake up in the morning. It's something to keep in mind.