Hello! First time post...
Almost a year ago my husband was diagnosed with CLL at 45 after a routine blood test. Since then his lymphocyte count has more than doubled (started at 41, currently over 100). In November after seeing a new specialist, he had a bone marrow biopsy and was told that he has a p53 deletion plus 13q deletion. He was supposed to start FCR in February but the Dr told us this has "thrown a spanner in the works" and is possibly thinking Ibrutinib along with FCR. Recently I read an article about Venetoclax clinical trials which sound promising for aggressive disease which I am going to ask the Dr about when we go back in February. Just wondering if any of you have had any experience with p53 deletions and what exactly this means for us for the future? Google certainly scares the crap out of me!
Thanks in advance!