My consultant said she preferred to not recommend Fludarabine because of it's high toxicity and resultant long term side effects and particularly because she considered me to be "young" and fit. I am 64. The treatment regime is 2 days per month for 6 months.
A trial called RIAltO comparing the use of Ofatumumab + Chlorambucil and Ofatumumab + Bendamustine was offered but I declined at this time. I was diagnosed in July 2013 and had a CT scan 3 weeks ago which showed my spleen to be bigger than my liver. Thus the beginning of treatment.