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Bendamustine
Diagnosed for CLL in 1995. 2013 : Leukeran + Rituximab In 2021 I received only 1 cycle of
Bendamustine
(90) + Rituximab. No further cycles because of hemolyse. 2024 Now possibly Venetoclax + ? Appointment with oncologist next friday. Not much of a help. Best regards, Dick
Diagnosed for CLL in 1995. 2013 : Leukeran + Rituximab In 2021 I received only 1 cycle of
Bendamustine
(90) + Rituximab. No further cycles because of hemolyse. 2024 Now possibly Venetoclax + ? Appointment with oncologist next friday. Not much of a help. Best regards, Dick
dickcll
in
CLL Support
4 months ago
Does anyone have CLL and MDS?
I was testing with low dose again with imbruvica at 140 mg I changed Doctors they did a Bone marrow Biopsy and determined that I am a notch 1 mutation and because of the original treatment of
Bendamustine
developed. MDS.
I was testing with low dose again with imbruvica at 140 mg I changed Doctors they did a Bone marrow Biopsy and determined that I am a notch 1 mutation and because of the original treatment of
Bendamustine
developed. MDS.
DaveCll
in
CLL Support
7 months ago
Acalabrutinib, venetoclax and obinutuzumab in relapsed CLL: Phase 2 CLL2-BAAG trial results from the German CLL Study Group
[/i] Of note is the optional inclusion of
Bendamustine
for debulking* and the MRD guided protocol [i] "All patients received the MRD-guided triple combination, and 18 received optional debulking with
bendamustine
prior to induction, which consisted of six 28-day cycles of the triple combination and
[/i] Of note is the optional inclusion of
Bendamustine
for debulking* and the MRD guided protocol [i] "All patients received the MRD-guided triple combination, and 18 received optional debulking with
bendamustine
prior to induction, which consisted of six 28-day cycles of the triple combination and
AussieNeil
Partner
in
CLL Support
4 months ago
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CLL survival times ARE improving, thanks to BTK and BCL-2 inhibitors
Those older chemoimmunotherapy treatments, typically
Bendamustine
+ Rituximab (BR) or Fludarabine + Cyclophosphamide + Rituximab (FCR), selected for tougher to treat sub-clones, which they cause through inducing DNA damage that will hopefully trigger apoptosis [u]if[/u] the TP53 gene isn't mutated or
Those older chemoimmunotherapy treatments, typically
Bendamustine
+ Rituximab (BR) or Fludarabine + Cyclophosphamide + Rituximab (FCR), selected for tougher to treat sub-clones, which they cause through inducing DNA damage that will hopefully trigger apoptosis [u]if[/u] the TP53 gene isn't mutated or
AussieNeil
Partner
in
CLL Support
5 months ago
first line treatment with bendamustin and rithoximab
I had 6 month first line treatment with bendamustin and rithoximab in 2022 september ended. .when i start my treatment my numbers was very high wbc 146 rbc was low in 2022 janeuary the numbers was wbc126 rbc 3.23 hgb 10.9 plt 135 LDh 920. because of high in ldh one of recent doctor said may be
I had 6 month first line treatment with bendamustin and rithoximab in 2022 september ended. .when i start my treatment my numbers was very high wbc 146 rbc was low in 2022 janeuary the numbers was wbc126 rbc 3.23 hgb 10.9 plt 135 LDh 920. because of high in ldh one of recent doctor said may be
09123836306
in
CLL Support
5 months ago
My chemo experience
Subsequent treatments (the next 4 months) were
bendamustine
and rituximab intravenous drips. No problems at all. The prognosis for
bendamustine
isn't as good as fludarabine - the likely effective period being 4 or 5 years as opposed to 15 years for fludarabine, but thats life.
Subsequent treatments (the next 4 months) were
bendamustine
and rituximab intravenous drips. No problems at all. The prognosis for
bendamustine
isn't as good as fludarabine - the likely effective period being 4 or 5 years as opposed to 15 years for fludarabine, but thats life.
kiwiCanuck
in
CLL Support
1 year ago
Diagnosed with CLL March 2022
I did
Bendamustine
and Rituxan. After my first treatment I was put in the hospital for a high temperature and very low wbc’s and neutrophils. I also had an allergic reaction to the Allupurinol they give you before chemo. They cut my
bendamustine
dose in half after that.
I did
Bendamustine
and Rituxan. After my first treatment I was put in the hospital for a high temperature and very low wbc’s and neutrophils. I also had an allergic reaction to the Allupurinol they give you before chemo. They cut my
bendamustine
dose in half after that.
Jbeebe
in
CLL Support
1 year ago
Median PFS for FCR treated CLL patients with IGHV-M was 14.6 years vs 4.2 years for patients with IGHV-UM. V+O and I+R look to be superior
Prior to the advent of targeted therapies, we only had chemoimmunotherapy treatments, typically BR (
bendamustine
+rituximab) or a very old drug chlorambucil to offer to most patients needing treatment.
Prior to the advent of targeted therapies, we only had chemoimmunotherapy treatments, typically BR (
bendamustine
+rituximab) or a very old drug chlorambucil to offer to most patients needing treatment.
AussieNeil
Partner
in
CLL Support
1 month ago
CLL relapse
She is taking
Bendamustine
monotherapy and was in remission about 3 years after treatment. Now she has one enlarged lymphnode in her armpit, her hematologist said that CLL is slowly coming back. Leukocites 7.7 Lymphocites 52% Everything else in her lab results and ultrasound is fine.
She is taking
Bendamustine
monotherapy and was in remission about 3 years after treatment. Now she has one enlarged lymphnode in her armpit, her hematologist said that CLL is slowly coming back. Leukocites 7.7 Lymphocites 52% Everything else in her lab results and ultrasound is fine.
Taupe7
in
CLL Support
2 years ago
Relative risk for secondary bone marrow cancer within 5 years after initial CLL chemoimmunotherapy treatment (typically BR or FCR)
I can't see any justification for
Bendamustine
+Rituximab (BR) treatment when targeted therapies are available. You don't see this curative effect with BR.
I can't see any justification for
Bendamustine
+Rituximab (BR) treatment when targeted therapies are available. You don't see this curative effect with BR.
AussieNeil
Partner
in
CLL Support
1 year ago
FDA Approves Zanubrutinib for Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphom
Findings from SEQUOIA showed that at a median follow-up of 25.0 months, the median progression-free survival (PFS) was not reached (95% CI, not estimable [NE]–NE) with zanubrutinib vs 33.7 months (95% CI, 28.1-NE) with
bendamustine
and rituximab (Rituxan; BR) in patients with treatment-naïve CLL/SLL
Findings from SEQUOIA showed that at a median follow-up of 25.0 months, the median progression-free survival (PFS) was not reached (95% CI, not estimable [NE]–NE) with zanubrutinib vs 33.7 months (95% CI, 28.1-NE) with
bendamustine
and rituximab (Rituxan; BR) in patients with treatment-naïve CLL/SLL
lankisterguy
Volunteer
in
CLL Support
2 years ago
CT thorax results: borderline lymphs
Hi everyone, My father has CLL/SLL from 2018 and had his first treatment at 2019 with
Bendamustine
and Rituximab because of very enlarged lymph nodes. After his treatment the lymph nodes decreaded to the original size.
Hi everyone, My father has CLL/SLL from 2018 and had his first treatment at 2019 with
Bendamustine
and Rituximab because of very enlarged lymph nodes. After his treatment the lymph nodes decreaded to the original size.
TOFK
in
CLL Support
2 years ago
Zanubrutinib PFS, ORR Is Superior to Ibrutinib for Relapsed/Refractory CLL/SLL
This application was based on earlier findings from an interim analysis of the ALPINE study along with phase 3 findings from the SEQUOIA study (NCT03336333), which showed improvements in PFS compared with
bendamustine
plus rituximab (Rituxan).
This application was based on earlier findings from an interim analysis of the ALPINE study along with phase 3 findings from the SEQUOIA study (NCT03336333), which showed improvements in PFS compared with
bendamustine
plus rituximab (Rituxan).
lankisterguy
Volunteer
in
CLL Support
2 years ago
1st treatment of bendamustine. Side Effects Help
1st week after 1st treatment of
bendamustine
. Is diarrhea normal side effect? Seems like a stomach bug but stool is oily. Thanks for help
1st week after 1st treatment of
bendamustine
. Is diarrhea normal side effect? Seems like a stomach bug but stool is oily. Thanks for help
LarryJM
in
CLL Support
2 years ago
Treatment-naive or relapsed CLL patients will soon have zanubrutinib/Brukinsa as a treatment option in the EU
In these two trials, BRUKINSA demonstrated superior efficacy versus either
bendamustine
plus rituximab (B+R) or ibrutinib in first-line or R/R CLL, respectively.
In these two trials, BRUKINSA demonstrated superior efficacy versus either
bendamustine
plus rituximab (B+R) or ibrutinib in first-line or R/R CLL, respectively.
AussieNeil
Partner
in
CLL Support
2 years ago
Zanubrutinib Bests Bendamustine-Rituximab in Previously Untreated CLL/SLL
More info here:https://www.cancertherapyadvisor.com/home/cancer-topics/chronic-lymphocytic-leukemia/zanubrutinib-bests-
bendamustine
-rituximab-cll-sll-previously-untreated/
More info here:https://www.cancertherapyadvisor.com/home/cancer-topics/chronic-lymphocytic-leukemia/zanubrutinib-bests-
bendamustine
-rituximab-cll-sll-previously-untreated/
Yalokin
in
CLL Support
2 years ago
2 months on Calquence
There was a time almost a decade ago that I was severely neutropenic from
Bendamustine
, so I'm not complaining about my high ANC, just wondering what my cause.
There was a time almost a decade ago that I was severely neutropenic from
Bendamustine
, so I'm not complaining about my high ANC, just wondering what my cause.
lpac
in
CLL Support
2 years ago
after bendamustine got covid
hi all after use
bendamustine
my numbers went down but unfortunately i got civid what should i do please help me thanks for sharing your thoughts
hi all after use
bendamustine
my numbers went down but unfortunately i got civid what should i do please help me thanks for sharing your thoughts
Hidden
in
CLL Support
2 years ago
To remove my port or not?
Hello, I am a 66 year old male, CLL for about 10 years, was in W &W until Feb, 2021, then completed 6 months treatment with
Bendamustine
and Rituximab in July 2021, two follow up appts. since then both went well with MRD at 0.07%. I had a Infusaport (port) placed for my treatment.
Hello, I am a 66 year old male, CLL for about 10 years, was in W &W until Feb, 2021, then completed 6 months treatment with
Bendamustine
and Rituximab in July 2021, two follow up appts. since then both went well with MRD at 0.07%. I had a Infusaport (port) placed for my treatment.
napa
in
CLL Support
2 years ago
Effects of Calquence on sperm
on Calquence for CLL, he's had Chemo at least three times over about 15 years, Bad reactions to Rituxan, weird skin issues, looked like tick bullseye rings that started on the upper torso traveled down his body, down his arms and legs and then disappeared, he was in remission after the last chemo...
Bendamustine
on Calquence for CLL, he's had Chemo at least three times over about 15 years, Bad reactions to Rituxan, weird skin issues, looked like tick bullseye rings that started on the upper torso traveled down his body, down his arms and legs and then disappeared, he was in remission after the last chemo...
Bendamustine
linnylee
in
CLL Support
2 years ago
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