LOOK 👀🤯Compass Pathways Psilocybin Clinical Trial Ongoing Right NOW🍄

[LifeIsThePitts]

gizmodo.com/psilocybin-depr...

This is an article from Nov '22 about MROC and Compass Pathways Psilocybin clinical trial that is still ongoing this year. I thought it would be helpful to post it for everyone to see the progress going on.

Here's a excerpt from the article...go to the link to read the whole story...

..."A study out this week is the largest of its kind to suggest that psilocybin—the key ingredient in psychedelic mushrooms—can be a potential treatment for depression. The randomized trial found that people with treatment-resistant depression who received a large dose of psilocybin along with psychological support experienced a significant reduction in symptoms up to three weeks later, as compared to those who took a much smaller dose of psilocybin.

The research is being funded by UK-based company Compass Pathways, which is hoping to develop its own proprietary form of synthetic psilocybin as a treatment for depression and other mental health conditions. Their latest results come from a Phase IIb trial that was conducted across 10 countries, including the U.S, and involved 233 volunteers with depression that hadn’t responded to at least two other treatments.

The volunteers were randomized to be given a single dose of psilocybin at three varying strengths: 1 milligram, 10 milligrams, or 25 milligrams. Before the trial, all the participants were given counseling to prepare them for the psychedelic experience. Following the treatment, they were monitored and told to focus inward while listening to a specially designed music playlist for about six hours. They then received two counseling sessions—the first a day later and the second a week later—meant to help them process the insights they might have gotten during the psilocybin trip. Finally, their mental health outcomes were tracked for 12 weeks.

The lowest dose of psilocybin that people received was intended as a control, since it was expected to have little to no therapeutic effect. Compared to this control dose, people on 25 milligrams of psilocybin experienced a significant reduction in symptoms from their baseline up to three weeks later. Those on the 10-milligram dose experienced a greater reduction of their symptoms as well, but the difference wasn’t statistically significant compared to those who took the 1-milligram dose. The findings were published Wednesday in the New England Journal of Medicine."

[Toddzen]

Those are very low dosages. To have a psychedelic experience the dose is 1- 3 grams. 1000mg equals One Gram.

[LifeIsThePitts in reply to Toddzen]

Yeah...I microdose with 0.15 g per day, 4-5 days a week. I have never taken more than 0.5 g per dose. Don't know if I'm ready for that MUCH of a trip.

[Radddd in reply to Toddzen]

I was confused about that as well. That’s a different way of expressing the concentration (25mg/70kg). As someone put it online:

My napkin math: 20mg is equivalent to roughly between 1.1g to 3.9g of dry weight (lots of variance in potency). This weight range is roughly equivalent to typical recreational dosages.

[LifeIsThePitts in reply to Radddd]

I started microdosing May 2, 4-5 times a week. As of today, still at 0.15 g doses, I get a predictable physical reaction every time. I took my dose at 5:45am. It's now 8:10am. Went for a 75 min walk with my dog and just finished eating breakfast. My vision is brighter and everything is crystal clear. Head feels lightweight and calm with just a whisper of headiness that is a welcoming feeling of relaxation. The only bad side effect I regularly experience is I can have some mild diarrhea after breakfast. But I don't have a gallbladder, so that could play a part in the only "negative" symptom I experience.

Have you microdosed or used psilocybin recreationally?

[Toddzen]

I have taken 1gr. a few times. Reality becomes very bright and magical looking. I have Seroquel which brings me down.

[Hidden]

Interesting research. I would love to try it but my doc is against it in my case. ☹️. Glad you’re feeling some good relief minus the stomach effects. Positive and negatives to everything I suppose. So happy to hear about Smokey. What a relief atm!! Hang in there and stay positive, you’re an inspiration to all of us!! 💛

[Marysblue]

Yes as Huey Lewis once said I want a new drug.