Like all medications it may take 4 - 6 weeks to fully kick in. If you feel worse before you start to feel the benefits don't stop taking them but go back to your GP asap.
So I have heard, but for me I had no issues stopping them. I think that it must largely depend on the person, but also what you are being switched over too and whether you have to stop it completely before starting a new medication or the 2 can be mixed (so venlafaxine lowered as the new ad is increased).
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