bio chemical recurrence

[Survivor1965]

The American urological association considers biochemical recurrence to be .2 post prostatectomy. Does anyone know what the number is for people that still have a prostate. ?

[Tall_Allen]

If you've had primary radiation, the standard biochemical recurrence is nadir+2.0

[Concerned-wife]

2.0. However, based on rapidly rising PSA, they might do a PSMA scan earlier than this and find recurrence. This is what happened to my husband

[Survivor1965 in reply to Concerned-wife]

Fortunately it’s not rapidly rising. It was roughly the same for him a year ago. I told him the doubling time is one of the most important things for him at this point.

[NanoMRI]

But are the guidelines correct? After my RP and salvage RT I had salvage lymph node surgery at 0.13 - six cancerous lymph nodes confirmed. All the best!

[Don717 in reply to NanoMRI]

Guidelines are just that...a general "guide". Not inclusive of the entire sampling qty. Just a number agreed upon by a majority (clinical & insurance driven). Just like "undetectable" which appears to have a value of anything anyone wants to make it. I've seen it as high as .1 and obviously as low as the 3 decimal tests. You already know what advocating for yourself can do!

I digress...OP is asking for folks with a prostate. TA has provided that "guideline". It's a messy number for sure but hey at least we have a built-in indicator that can help us track/find/treat our PC!

[NanoMRI in reply to Don717]

Yes, you are correct the OP asked about guidelines for men with prostates. Although I no longer have one, the 'guideline' for with and without are as you say, just a general guide. If it is cancer at the guidelines, how is it not cancer at lower values rising to the applicable established guideline value?

I commented as I choose to not give this beast time and obscurity, and in my humble opinion, this applies to men fighting metastatic prostate cancer with and without a prostate gland. All the best to all of us navigating all the information and disparities.

[Don717 in reply to NanoMRI]

I agree with you. If my PSA results come back (.02 is the low parameter of my test) with anything other than a "<" sign in front, it's time to do work!! As did you!

[dhccpa in reply to Don717]

Even the term "castrate resistant," which I may or may not be at present, has different interpretations. My PSA has risen over the last two years, but scan results arguably are better than ever. I still have my prostate although it's being radiated out of useful existence as we speak.

[RMontana]

see if u can follow this thread. Lots of discussion. TNX Rick

healthunlocked.com/advanced...

[Survivor1965 in reply to RMontana]

Thank you. Great article.

[Survivor1965]

thank you so much everyone

[NecessarilySo]

Biochemical recurrence, in essence, means that there are prostate cancer cells in the body after treatment, be it RP or RT. However, if someone has not had RP or RT then they might have been treated with ADT to control, for example, BHP, and then their prostate is intact and can generate PSA normally. I would think that someone who has opted for ADT only to control prostate problems would follow the same guidelines as someone who has not yet been diagnosed with PC or APC. That used to be 4 mg/ml but nowadays is 2.5-3.

verywellhealth.com/the-mean...

"While some healthcare providers still use 4.0 or higher as the cutoff point at which to start a cancer investigation, others start much earlier at 3.0 or even 2.5. There is some rationale for earlier intervention."

[Mgtd]

This may help.

pmc.ncbi.nlm.nih.gov/articl...