I just started Zytiga and at the age ... - Advanced Prostate...

Advanced Prostate Cancer

22,371 members28,137 posts

I just started Zytiga and at the age of 86 I'm finding it difficult to climb stairs; I do have a slow heartbeat when at rest: mid to high 40

Poollover profile image
14 Replies

I just started Zytiga and at the age of 86 I'm finding it difficult to climb stairs; I do have a slow heartbeat when at rest: mid to high 40s. I've been on Orgovyx for 3 months, when I added Xytiga, which was added because Orgovyx was only able to bring my PSA from 12 to 1.8. Thoughts, Terry

Written by
Poollover profile image
Poollover
To view profiles and participate in discussions please or .
Read more about...
14 Replies
GP24 profile image
GP24

ADT causes muscle loss which explains why you find it difficult to climb stairs. The three months of Orgovyx are long enough to make it noticable.

Grandpa4 profile image
Grandpa4

it is frustrating that many physician do not tell patients that they must lift weights to prevent muscle loss when going on these drugs. I don’t think it is too late for you to start now.

Poollover profile image
Poollover in reply toGrandpa4

I do work my leg muscles almost every day, and after a few days I can now climb stairs as before. Starting Zytiga made me nervous, but now I have adjusted to it.

Ztlf profile image
Ztlf

That is a very low heartbeat. Have you contacted a cardiologist (actually, an electrocardiologist, who works with heartbeat and pacemakers). My husband's MO had to adjust the prednisone dose (prednisone must be taken with Zytiga).

Poollover profile image
Poollover in reply toZtlf

I'm taking 5-mg of Prednisone, maybe I should take 10-mg.

Explorer08 profile image
Explorer08

Technically, you have bradycardia. I get bradycardia on rare occasions. My cardiologist has mentioned that if my bradycardia worsens then a pacemaker would be necessary. You should consider checking your oxygen level at home on a regular basis.

Poollover profile image
Poollover in reply toExplorer08

I have always had a slow beat, but was, a very long time ago, a professional athlete. Four wall handball and tennis are aerobic demanding sports. My 02 is always above 95, and working out it goes from 99 to 100. My initial response to Zytiga made me nervous, I'm okay now. My problem, apart from stage 4 cancer, is that I'm old. Thanks for your input.

Ztlf profile image
Ztlf in reply toPoollover

The Zytiga/Eligarde combo has been very helpful for my husband. Best of luck to you!!

Poollover profile image
Poollover in reply toZtlf

Thanks.

Jeremiad53 profile image
Jeremiad53

Physical activity increases the feeling, but over time it decreases. Use it or lose it. I got palpitations, which told me that I needed to strengthen the heart muscle. So I walked 3 miles, and bicycled 1 mile then increased it to 1.5, up to 5 miles over 10 days or so. I am 70, and am amazed what exertion can improve physical health, especially after Chemo. Never say never, but another round of that? NO thank you Mimi, we can discuss that when it is time.

Poollover profile image
Poollover in reply toJeremiad53

Thanks, and I could not agree with you more about exercise, especially aerobic work. Even at 86 I still work out. 🏃

OldGuysRule profile image
OldGuysRule

Zytiga had been very difficult for me. I’m actually considering dropping it. But, all the best to you sir!

Poollover profile image
Poollover in reply toOldGuysRule

Actually, after a few days on Orgovyx (Orgovyx for 3 months) and Zytiga things have settled down and I seem able to handle those two drugs. I just hope that they will be able to put my cancer to sleep for a couple of years. My current goal is to make it to 90 with a reasonable quality of life.

OldGuysRule profile image
OldGuysRule

may God bless and keep you sir

Not what you're looking for?

You may also like...

Has anyone had a little increase in Testosterone when they added Xtandi or others ARSi ?

Dad was on orgovyx for a couple of months and his Testosterone levels had come down to 26. Around...
Tinkudi profile image

Orgovyx - Kidney issues

I started Orgovyx this past Wednesday with the recommended triple dose. Yesterday my BP was...
SCreader profile image

Orgovyx dosage when on Erleada

I've been on 3 month Eligard shots for almost 2 years. I started with Xtandi at the same time but...
Atlpapa profile image

Erleada side effects

Would like to hear from those with personal experience that have added Erleada to ADT ( Lupron,...
wilcoxsaw profile image

PSA seems stuck around 1.0 while on Orgovyx and Nubequ

After a few months experimenting with Nubeqa as a monotherapy, and seeing PSA climb to around 4.0,...
joeguy profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.