Declining psa #5

[Nfler]

Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries 🍒 and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to say my psa dropped another .19 points to 1.47 from 1.66. While I asked my med oncologist if it’s a concern that psa wasn’t dropping after it stabilized he said absolutely not, but that it would be if it started rising and or doubling. Again I’m not recommending anyone try this as everyone’s body reacts differently, just stating the facts of my experience and anyone can come to their own conclusion, maybe even have a conversation w their mo…Good luck all n keep up this fight against this dreaded disease w as much of an open mind as possible…

[Papillon2]

Good. Pull out all the stops!

[irakor]

B17/Amygdalin really is a strong anticancer medicine. But it is dangerous to get it from the seeds yourself because you may overdose. You can buy it in capsules from Apricot Power or somewhere else. The dose should be 4 or 5 100 mg capsules depending on your weight. You'd better discuss the dose with your MO or with an alternative doctor. My husband takes 4 100 mg tablets daily, his weight is 166 pounds. Good luck!

[Nfler in reply to irakor]

Thank you irakor, I gradually increased my seed consumption w absolutely no side effects at 3-5 cherry seeds or two plum or peach seeds daily. Not to mention I love the way they taste, kind of a cherry 🍒 almond..😁😎

[irakor in reply to Nfler]

Hi Nfler, I understand that you like the taste of fruit pits. I believe you know that Laetrile (Amygdalin) contains cyanide. So the side effects of laetrile are the same as those of cyanide. Please see cancerresearchuk.org/about-.... So it would be safe not to choose the dose yourself. Ask your doctor! I wish you good luck!

[Nfler in reply to irakor]

Yes the cyanide is what works like natural chemo, it kills the pca n leaves the natural cells alone. Also the body seems to absorb the Laetrile better when it’s in its natural form of amygdalin. I’ve been slowly increasing my intake n doesn’t seem to bother me at all, as soon as I get a headache or diarrhea then I’ll slow down

[irakor in reply to Nfler]

Sorry, I misread your first reply. 3-5 fruit pits are safe, but will not produce the desired effect. We bought apricot pits, my husband took 27 pits a day (9 pits 3 times a day) on his doctor's advice, his weight was 200 or 210 pounds at the time. You can recalculate to your weight or better ask an alternative doctor. 3-5 pits are also useful, but are unlikely to affect PSA.

[Nfler in reply to irakor]

Oh great that’s exactly what I desired to figure out the precise dosage. I’m 219, roughly about the same as your husband, so I will work my way up to that level, though the psa is what dropped.19 after 3-5 pits daily. Peach 🍑 n apricot pits seem to b 3x the size, so do u know the rec dose for them. I assume 1/3 which would b nine daily or 3/3x daily…

[irakor in reply to Nfler]

I am not a doctor, I can only say which dosage my husband's doctor advised. We bought Organic Bitter Raw Apricot Kernels from Vitamin Depot yourvitamindepot.bizhosting.... The doctor advised to take 27 kernels per day, my husband was a little over 200 pounds at that time. It is dangerous to take more.

Did you also try Red raspberry seed powder, 2 tee spoons per day? It is a mighty anti-cancer medicine causing apoptosis of cancer sells . Please see jonbarron.org/article/truth.... I bought it from Botanic Innovations. Good luck!

[Nfler in reply to irakor]

Oh great thank you for the update. I haven’t tried the raspberry powder but def interested as I know the berries r extremely good anti oxidants/ cancer ♋️ killers…

[85745]

First let me say Congrats ! This is great to hear, I am taking Fenben but added Ivermectin 3 days on /4 off. 40mg IVM . weight 200lb. What was your dose / weight and how many days a week. I need to restart my B17 again , I was taking the apricot seed meal , still put some in my coffee . Also take Fisetin / Fenugreek ( absorb ). Liposomal Artemisinin, Curcumin/ Lactoferrin ( absorb and synergy ) My detox is Tudca and Mod Citrus Pectin ( mcp) . Yes vitamin D3, k1/k2, C, Bcomplex slow release, A. ALso Garlic Quercetin , Boron , Alpha Lipoic Acid . Before bedtime L Theanine, Apigenin, Melatonin. The Fisetin is 1wk on 1wk off, but the Fenugreek is daily. No sugar, carbs, red meat, egg yolks, dairy. My pitfall is light cream in coffee. Started Elderberry flower tea , Organic Cocao Nibs , Not a fan of Green tea. It's tough finding the time for all this but.... Just read your earlier post on dosage, Thanks keep up the good work

[Nfler in reply to 85745]

Wow 85, that’s quite the regiment, I’m no where near as diligent but am getting the good results and I think adding the Cherry pits really helped it drop another.19 points. I will def look into a few more of your supplements as they all seem to be effective. Is your psa remaining stable…

[Graham49]

I searched online for evidence whether amygdalin is effective against prostate cancer. I could only find in-vitro and mouse studies. Here is one of the better recent studies.

Amygdalin Exerts Antitumor Activity in Taxane-Resistant Prostate Cancer Cells

by Igor Tsaur 1,†ORCID, Anita Thomas 1,*,†, Michelle Monecke 2, Marion Zugelder 2, Jochen Rutz 2, Timothy Grein 2, Sebastian Maxeiner 2, Hui Xie 2ORCID, Felix K.-H. Chun 2, Florian Rothweiler 3,4, Jindrich Cinatl, Jr. 3,4, Martin Michaelis 5ORCID, Axel Haferkamp 1 and Roman A. Blaheta 1

1 Department of Urology and Pediatric Urology, University Medicine Mainz, Langenbeckstr. 1, 55131 Mainz, Germany

2 Department of Urology, Goethe-University, 60590 Frankfurt am Main, Germany

3 Institute of Medical Virology, Goethe-University, 60596 Frankfurt am Main, Germany

4 Petra Joh-Forschungshaus, 60528 Frankfurt am Main, Germany

5 Industrial Biotechnology Centre, School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK

*Author to whom correspondence should be addressed.

†These authors contributed equally.

Cancers 2022, 14(13), 3111; doi.org/10.3390/cancers1413...

Received: 29 May 2022 / Revised: 17 June 2022 / Accepted: 23 June 2022 / Published: 24 June 2022

Simple Summary

The natural compound amygdalin is popular among tumor patients as an alternative treatment option. However, knowledge about its precise mode of action remains poor. In the present study, amygdalin is shown to inhibit growth and disseminative properties of taxane-resistant prostate cancer cells. Further investigation is warranted to determine the role of amygdalin in the setting of metastasized prostate cancer.

Abstract

Despite recent advances in the treatment of metastatic prostate cancer (PCa), resistance development after taxane treatments is inevitable, necessitating effective options to combat drug resistance. Previous studies indicated antitumoral properties of the natural compound amygdalin. However, whether amygdalin acts on drug-resistant tumor cells remains questionable. An in vitro study was performed to investigate the influence of amygdalin (10 mg/mL) on the growth of a panel of therapy-naïve and docetaxel- or cabazitaxel-resistant PCa cell lines (PC3, DU145, and LNCaP cells). Tumor growth, proliferation, clonal growth, and cell cycle progression were investigated. The cell cycle regulating proteins (phospho)cdk1, (phospho)cdk2, cyclin A, cyclin B, p21, and p27 and the mammalian target of rapamycin (mTOR) pathway proteins (phospho)Akt, (phospho)Raptor, and (phospho)Rictor as well as integrin β1 and the cytoskeletal proteins vimentin, ezrin, talin, and cytokeratin 8/18 were assessed. Furthermore, chemotactic activity and adhesion to extracellular matrix components were analyzed. Amygdalin dose-dependently inhibited tumor growth and reduced tumor clones in all (parental and resistant) PCa cell lines, accompanied by a G0/G1 phase accumulation. Cell cycle regulating proteins were significantly altered by amygdalin. A moderate influence of amygdalin on tumor cell adhesion and chemotaxis was observed as well, paralleled by modifications of cytoskeletal proteins and the integrin β1 expression level. Amygdalin may, therefore, block tumor growth and disseminative characteristics of taxane-resistant PCa cells. Further studies are warranted to determine amygdalin’s value as an antitumor drug.

[Nfler in reply to Graham49]

Graham thanks for the thorough breakdown but that’s what I keep reading is that further studies need to be done but they don’t do them n we all probably know why. Since it’sa natural fruit n has the almond looking seed in it, I’ma believer in moderate Rec doses previously taken and so far it dropped the psa .19 points after just a cpl weeks of doing so…

[Mikeski]

Good news. What is the Ivermectin doing for you against the PC? I had never heard of it till some folks claimed it helped against COVID back before vaccines.

[Nfler in reply to Mikeski]

Well there’s strong research on it's ability to cause Ao1/k1-k2 apoptosis of adv Pca cells and until I started taking it my psa would go to 6-7 when I would get off adt and now it remains at 1.5-1.7, then I started the natural amygdalin n it dropped further to the current 1.47

[Mikeski in reply to Nfler]

Excellent, thanks.

[Thinus]

There is already a lot of research available on the internet about ivermectin killing cancer. Some use it in combination with Abendazole.

AGAIN: be careful for overdose. Read up a lot of how the half life of this stays in your bloodstream.

And good luck. Throw your cancer with everything available in the kitchen.

[BB_1 in reply to Thinus]

I take IVM and Mebendazole.

[Nfler in reply to BB_1]

Has it kept your psa stable

[Nfler in reply to Thinus]

Yes thinus, that’s why I only take it 4 days a week at 19 mg/day and have taken up to 48mg/day but it seems to make my eyes a little sensitive to night lights especially green but at current dose no problems. I bump it up a little if there’s any rise in psa…

[BB_1]

IVM did lower my PSA before I got my proton radiation treatments in May. IVM did drop it some. Anyway, I still take IVM.

[Thunderball1 in reply to BB_1]

What dosage do you find best?

[Nfler in reply to Thunderball1]

I personally like 19mg/day 4x/week with no side effects n stable psa

[dhccpa]

Looks like you've had quite a bit of standard treatment, and your measuring periods are short, so difficult to say. I'm at 5 years now on regular treatment, 3.5 years on alternatives, but I wouldn't attribute anything solely to the alternatives. Just a thought.

[Nfler in reply to dhccpa]

Yes I agree it’s still very early but glad psa is going down n not up. I wish I would’ve given these alternative trx a before removing my prostate but chickened out to what Drs were telling me n didn’t know about ivm or amygdalin at the time but it is what it is now. How is your psa responding and have you tried the alternatives solely on their own w no adt..?

[dhccpa in reply to Nfler]

No, I'm on ADT. PSA was just under 1 on June 30. It's bounced from 0.6 to 1.4 and down to 0.5 and back up. Yes, I've used quite a few alternatives, including fenben and I'mectin.

[Nfler in reply to dhccpa]

Oh that’s great news. My MO said since my psmA scan showed spread only to the LNodes that he’s not going to take another psmA till psa hits 4-5. He is surprised n pleased the psa has remained low n stable these last 7 months after getting off adt n stated as long as It’s working let’s stay w it, also when I got off adt I took 40-48 mg/every other day for a total of six doses n then the maintenance of 19mg/4x week…