Started Xtandi

[GTTown]

Hello everyone,

After almost 3.5 years, my PSA has gone down (from 577 to 4.23), and now it has started to go up again (9.5). So the Firmagon, Docetaxel and Radiation seemed to do a decent job. Now I've started Xtandi and after 3.5 weeks, a new low of 3.53! Doctor was very encouraged to see such a positive response. And luckily no side effects.

Does anyone have any feedback on the long term use or effectiveness of Xtandi?

[PSA680]

That’s great news GTTown - I started taking Xtandi 13 May 20-in combination with ADT (firmagon) - psa reduced from 680 to >0.05 by Nov 20 & (touch wood & thanking my fortune) is still at this nadir. Difficult to differentiate side effects of ADT from Xtandi but they’re tolerable. Good luck my brother

[GTTown in reply to PSA680]

Thanks, appreciate the feedback.

[Kaliber]

there’s been a whopping lot of talk about Xtandi on the group over time. I think xtandi has risen to a new level of appreciation in its ability to be “ very “ effective for long time care for many.

I’ve been on it about 55 months and my psa remains <0.1 . I’m very sensitive to it. Xtandi quite literally saved me from the jaws of inpatient hospice , so far.

Some guys ( me for example ) experience the most severe SEs. , but by far, most seem to be in the mild to moderate group. I’ve tolerated it and developed “ workarounds “ for some of the most severe SEs. I’ve lost most of my mobility , for example, but for me it’s well worth it and I’ve had and continue to have lots of great QOL time with my family …in the extra time it has bought me.

I hope you have great results with Xtandi as well, ….mostly it’s gonna all be about how aggressive your species of aPCa is and how much it responds to Xtandi. It’ll be good if your psa drops down to <0.1 slowly over a bit of time ….say , two to three months to nadir. Best of luck with your new regimen brother.

💪💪💪❤️❤️❤️

[Benkaymel]

I've been on Xtandi for about 7 months and in general the SEs have been moderate - fatigue and hot flushes being the main ones but some of this is due to being on Prostap as well. Exercise has helped the fatigue and I'm trying sage tablets and evening primrose oil for the hot flushes.My PSA has slowly reduced from 13 at diagnosis to 0.12 at latest test and my bone pain has reduced to some dull aches so I've done pretty well on it so far.