well I finally got to meet with y Oncologist last week regarding use of estradiol (e2) patch to battle against osteoporosis / osteopenia because the 90 day Xgeva dosing (down from every 28 daysx 2 years) doesn't seem to be doing much. He claims the possible cardiovascular side effects from the PATCH is not worth the risk. I'm confused, I thought the whole purpose for development of a trans dermal administration of the e2 virtually eliminated the cardio side effects. I like my team, but should I be concerned that he views e2 the same as oral estrogen? And, should I seek a second opinion....Xgeva hasn't prevented fractures, and my density is-2.3 in femoral neck and -1.5 in lumbar spine and hip.
Is it possible for the e2 patch to help strengthen and correct the bone loss I've already suffered from 4 years of ADT.